Q9HQ86 (RNP2_HALSA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 2
Short name=RNase P component 2
EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	VNG_1279H

Organism

Halobacterium salinarium (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)

Taxonomic identifier

64091 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length	164 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00755
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 164	164	Ribonuclease P protein component 2 HAMAP MF_00755		PRO_0000140018

Sequences

	Sequence		Length	Mass (Da)
	Q9HQ86 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 2BFBF95D64972F5B	FASTA	164	17,891
	10 20 30 40 50 60 MKHLPKHVRP RWRYLAVGIE AWPDAGIERS DFQRALWFAA GNLLGDPGSA DAGVRVVAYS 70 80 90 100 110 120 FRDGRGEALV RARRGTVSRA RAAVACVSAV REHPVRVCVR GVSGTMRAAR ERYLDGLDTP 130 140 150 160 ERRSDVAFDG DARDGVCRGE NVDVVAGDDG WVGARRRDCG TDGE

References

[1]

"Genome sequence of Halobacterium species NRC-1." Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D., Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D., Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K. , Cruz R., Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P., Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M., Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J., Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L., DasSarma S. Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000) [PubMed: 11016950] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700922 / JCM 11081 / NRC-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004437 Genomic DNA. Translation: AAG19630.1.
PIR	B84283.
RefSeq	NP_280150.1. NC_002607.1.
3D structure databases
ProteinModelPortal	Q9HQ86.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1447929.
GenomeReviews	Gene locus VNG_1279H in contig AE004437_GR.
KEGG	hal:VNG1279H.
NMPDR	fig|64091.1.peg.1169.
Phylogenomic databases
HOGENOM	HBG498069.
OMA	RACEEKY.
ProtClustDB	CLSK2517860.
Enzyme and pathway databases
BioCyc	HSP64091:VNG1279H-MONOMER.
Family and domain databases
HAMAP	MF_00755. RNase_P_2. [Tree]
InterPro	IPR002759. RNase_P/MRP_subunit. [Graphical view]
KO	K03537.
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP2_HALSA

Accession

Primary (citable) accession number: Q9HQ86

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	March 1, 2001
Last modified:	November 16, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program