ID   Q9HPW6_HALSA            Unreviewed;       420 AA.
AC   Q9HPW6;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   27-MAR-2024, entry version 109.
DE   SubName: Full=Htr12 transducer {ECO:0000313|EMBL:AAG19751.1};
GN   Name=htr12 {ECO:0000313|EMBL:AAG19751.1};
GN   OrderedLocusNames=VNG_1442G {ECO:0000313|EMBL:AAG19751.1};
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium; Halobacterium salinarum NRC-34001.
OX   NCBI_TaxID=64091 {ECO:0000313|EMBL:AAG19751.1, ECO:0000313|Proteomes:UP000000554};
RN   [1] {ECO:0000313|EMBL:AAG19751.1, ECO:0000313|Proteomes:UP000000554}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1
RC   {ECO:0000313|Proteomes:UP000000554};
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.W., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE004437; AAG19751.1; -; Genomic_DNA.
DR   PIR; C84298; C84298.
DR   AlphaFoldDB; Q9HPW6; -.
DR   STRING; 64091.VNG_1442G; -.
DR   PaxDb; 64091-VNG_1442G; -.
DR   KEGG; hal:VNG_1442G; -.
DR   PATRIC; fig|64091.14.peg.1101; -.
DR   HOGENOM; CLU_000445_116_1_2; -.
DR   InParanoid; Q9HPW6; -.
DR   OrthoDB; 8523at2157; -.
DR   PhylomeDB; Q9HPW6; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00283; MA; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000554};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}.
FT   DOMAIN          10..50
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          141..377
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          391..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          191..256
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          289..337
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        405..420
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   420 AA;  44106 MW;  1F71AC7374B5AA06 CRC64;
     MGEEVWRGAL SQFFTAFPEP LFVVDRDGTV VLWNDAIVEM TGVEAADAVG TPSIELFGTE
     GETQTLAEAV LERGEAIRET SVRTSELPAG AQHAKASATP LHNDGAVIGA VEVLTIVTDV
     VEQRERVKRA QRTLTDDVEA AVTELRDVGE GVADASQEIS DLAAEQASDV NDIAADVSDL
     SATIQEVAAS ADEVRQRSTE ARERAEASRE AAERVLAAVE AFADAGDTVS VNTASLREHL
     DEIDQLVDVI NDIADQTNML ALNANIEAAR AGEDGSGFSV VAEEVKDLAE QSQQQVGDIE
     ALVADIEADS EETAKSVAAA NDQVSSARTA AEELVENQDA IASAIGETAE GIAEIAAATD
     EQAETAAEIS AAIDTVVERA DAVADETADV AAANEQQTDM LSDIEQSVRD AERVLTSDDE
//