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Q9HPG4

- TRPF_HALSA

UniProt

Q9HPG4 - TRPF_HALSA

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
    Short name:
    PRAI
    Gene namesi
    Name:trpF
    Ordered Locus Names:VNG_1648G
    OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
    Taxonomic identifieri64091 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
    ProteomesiUP000000554: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 218218N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154400Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi64091.VNG1648G.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9HPG4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.Curated

    Phylogenomic databases

    eggNOGiCOG0135.
    KOiK01817.
    OMAiETHDWER.
    PhylomeDBiQ9HPG4.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9HPG4-1 [UniParc]FASTAAdd to Basket

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    MTRVKVCGLT TERDHAAAVA AGADAVGIIA DVPVETPREV SVETATALRA    50
    ATPPFVTSVL VTMPATPEHA VDLVRTVAPD AVQLHGDLPV GDAAYVAANT 100
    PCPVIKAVTA GDQSAARYAD VVDALLVDSP PTDDAGAGGG TGRTHDWAAT 150
    RAFADRVDTP VVLAGGLTPA NVADAVDTVD PFAVDVASGV EARPGEKDHA 200
    AVSAFVARAT ATPDPTLT 218
    Length:218
    Mass (Da):21,903
    Last modified:March 1, 2001 - v1
    Checksum:i2F916B7E1E10B7F3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004437 Genomic DNA. Translation: AAG19903.1.
    PIRiC84317.
    RefSeqiNP_280423.1. NC_002607.1.

    Genome annotation databases

    EnsemblBacteriaiAAG19903; AAG19903; VNG_1648G.
    GeneIDi1448202.
    KEGGihal:VNG1648G.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004437 Genomic DNA. Translation: AAG19903.1 .
    PIRi C84317.
    RefSeqi NP_280423.1. NC_002607.1.

    3D structure databases

    ProteinModelPortali Q9HPG4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 64091.VNG1648G.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG19903 ; AAG19903 ; VNG_1648G .
    GeneIDi 1448202.
    KEGGi hal:VNG1648G.

    Phylogenomic databases

    eggNOGi COG0135.
    KOi K01817.
    OMAi ETHDWER.
    PhylomeDBi Q9HPG4.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700922 / JCM 11081 / NRC-1.

    Entry informationi

    Entry nameiTRPF_HALSA
    AccessioniPrimary (citable) accession number: Q9HPG4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 27, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3