Q9HPB8 (RL6_HALSA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L6P

Alternative name(s):
HL10

Gene names

Name:	rpl6p
Ordered Locus Names:	VNG_1709G

Organism

Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) [Reference proteome] [HAMAP]

Taxonomic identifier

64091 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium › Halobacterium salinarum

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center By similarity. HAMAP-Rule MF_01365
Subunit structure	Part of the 50S ribosomal subunit By similarity.
Sequence similarities	Belongs to the ribosomal protein L6P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.2
	Chain	2 – 178	177	50S ribosomal protein L6P HAMAP-Rule MF_01365		PRO_0000131084
Experimental info
	Sequence conflict	36	1	Y → Q AA sequence Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q9HPB8 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 27CA9DFAF7214B85	FASTA	178	19,607
	10 20 30 40 50 60 MARVEIEIPD DVTAEVDHLD LTVEGPEGSV TRRLWYPDVD VSVEDDAVVV ASEVDDAKTD 70 80 90 100 110 120 STVGTFESHV ANMFHGVSEG WEYKLEVHYS HFPMQVDVEG EEVVIQNFLG EKAARRTQIR 130 140 150 160 170 GDTDVVVDDE EVTLSGPSIE DVGQTAADIE QLTRVTDKDT RVFQDGVYIV EKPAKGGA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of Halobacterium species NRC-1." Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D., Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D., Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K. , Cruz R., Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P., Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M., Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J., Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L., DasSarma S. Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700922 / JCM 11081 / NRC-1.
[2]	"Purification, properties, and N-terminal amino acid sequence of certain 50S ribosomal subunit proteins from the archaebacterium Halobacterium cutirubrum." Matheson A.T., Yaguchi M., Christensen P., Rollin C.F., Hasnain S. Can. J. Biochem. Cell Biol. 62:426-433(1984) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-37.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004437 Genomic DNA. Translation: AAG19952.1.
PIR	D84323. S08552.
RefSeq	NP_280472.1. NC_002607.1.
3D structure databases
ProteinModelPortal	Q9HPB8.
SMR	Q9HPB8. Positions 3-173.
ModBase	Search...
Protein-protein interaction databases
STRING	64091.VNG1709G.
Proteomic databases
PaxDb	Q9HPB8.
PRIDE	Q9HPB8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAG19952; AAG19952; VNG_1709G.
GeneID	1448253.
KEGG	hal:VNG1709G.
Phylogenomic databases
eggNOG	COG0097.
KO	K02933.
OMA	RDTRIFQ.
ProtClustDB	PRK05518.
Family and domain databases
Gene3D	3.90.930.12. 2 hits.
HAMAP	MF_01365_A. Ribosomal_L6_A.
InterPro	IPR000702. Ribosomal_L6. IPR020040. Ribosomal_L6_a/b-dom. IPR002359. Ribosomal_L6_CS2. IPR019907. Ribosomal_L6P_arc. [Graphical view]
PANTHER	PTHR11655. PTHR11655. 1 hit. PTHR11655:SF1. PTHR11655:SF1. 1 hit.
Pfam	PF00347. Ribosomal_L6. 2 hits. [Graphical view]
PIRSF	PIRSF002162. Ribosomal_L6. 1 hit.
SUPFAM	SSF56053. Ribosomal_L6. 2 hits.
TIGRFAMs	TIGR03653. arch_L6P. 1 hit.
PROSITE	PS00700. RIBOSOMAL_L6_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL6_HALSA

Accession

Primary (citable) accession number: Q9HPB8
Secondary accession number(s): P05968

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2004
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 66 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program