Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9HP81

- HTR2_HALSA

UniProt

Q9HP81 - HTR2_HALSA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Sensory rhodopsin II transducer

Gene

htr2

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Transduces signals from the phototaxis receptor sensory rhodopsin II (SR-II) to the flagellar motor. Responds to light changes through the variation of the level of methylation. Also acts as a chemotransducer.1 Publication

GO - Molecular functioni

  1. photoreceptor activity Source: UniProtKB-KW

GO - Biological processi

  1. chemotaxis Source: UniProtKB-KW
  2. protein-chromophore linkage Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Photoreceptor protein, Receptor, Transducer

Keywords - Biological processi

Chemotaxis, Sensory transduction

Keywords - Ligandi

Chromophore

Names & Taxonomyi

Protein namesi
Recommended name:
Sensory rhodopsin II transducer
Alternative name(s):
HTR-II
Methyl-accepting phototaxis protein II
Short name:
MPP-II
Gene namesi
Name:htr2
Synonyms:htrII
Ordered Locus Names:VNG_1765G
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
ProteomesiUP000000554: Chromosome

Subcellular locationi

Cell membrane By similarity; Multi-pass membrane protein By similarity

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini2 – 1615CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei17 – 3721HelicalSequence AnalysisAdd
BLAST
Topological domaini38 – 278241ExtracellularSequence AnalysisAdd
BLAST
Transmembranei279 – 29820HelicalSequence AnalysisAdd
BLAST
Topological domaini299 – 764466CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 764763Sensory rhodopsin II transducerPRO_0000110549Add
BLAST

Post-translational modificationi

Methylated by CheR.By similarity

Keywords - PTMi

Methylation

Proteomic databases

PaxDbiQ9HP81.
PRIDEiQ9HP81.

Interactioni

Protein-protein interaction databases

STRINGi64091.VNG1765G.

Structurei

3D structure databases

ProteinModelPortaliQ9HP81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini303 – 35553HAMP 1PROSITE-ProRule annotationAdd
BLAST
Domaini397 – 45054HAMP 2PROSITE-ProRule annotationAdd
BLAST
Domaini469 – 705237Methyl-accepting transducerPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 HAMP domains.PROSITE-ProRule annotation
Contains 1 methyl-accepting transducer domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0840.
InParanoidiQ9HP81.
OMAiIVEQTNM.
PhylomeDBiQ9HP81.

Family and domain databases

InterProiIPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view]
PfamiPF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view]
SMARTiSM00304. HAMP. 2 hits.
SM00283. MA. 1 hit.
[Graphical view]
PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9HP81-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGSGLVARIR GSYGTKLTLA LVVVVVLSVG VGTFVYQQTT TQLETDVRAD
60 70 80 90 100
LTGSADARAD HLDAWLSNAR GQTQLASRHP VLASGNDTAI TRYLEGLAAS
110 120 130 140 150
DERPDGVVAA HVYNTSTTTI EASSADAFTG VNPREQGAPF ATDPPSFATT
160 170 180 190 200
SDVVVAAPFT VPAADFPVLS VLSPIPGTTD KALIYMVNVN TLTDDFGQNV
210 220 230 240 250
AGSTTTVVSA DGTYVSHPDQ DRVLTGHDGP SRLLNQSRTQ PAYIDANGTV
260 270 280 290 300
TAAAPVDGAP WSVLVRAPHD RAFALGDFVA SSLVGLVLIT IVSLSLIGVT
310 320 330 340 350
VGSTTVTALR QFSRRADEMA AGDLDTDIDT SRNDEFGTLA ESFRSMRDSL
360 370 380 390 400
SESLTDAERA TARAEDARED AEQQRADAEA AREDAEAARK DAQETARALE
410 420 430 440 450
SAAADYEEAL TAVADGDLTR RVDASRDHDA MARIGHALND MLDDIETSVA
460 470 480 490 500
AATAFSDHVS DAAQRVEADA GDAIDAGTDV STAVDEISDG ATEQTDRLHE
510 520 530 540 550
VAGEVDDLSA SAEEVAETVA SLADTAGQAA SAVDDGRQAT EDAVETMDDV
560 570 580 590 600
ADDAEAAADA MDALDSEMAD IGEIVDVIAD IADQTNMLAL NASIEAARTG
610 620 630 640 650
ADGDGFAVVA DEVKTLAEES RDAAEDIESR LLALQGQVSD VADEMRATSD
660 670 680 690 700
TVSDGRATVG DAATALDDVV SFVADTDTAA GEIRAATDRQ AHAASRVASA
710 720 730 740 750
VDEVAGISQE TAAQATAVAD SAATQTDTLS SVDDAAADLA DRAAALDDLL
760
AEFDAHDDTE PEDY
Length:764
Mass (Da):79,042
Last modified:January 23, 2007 - v2
Checksum:iD5EB26F706576996
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti107 – 1104VVAA → RWFAG in AAC44369. (PubMed:8710852)Curated
Sequence conflicti682 – 6821E → Q in AAC44369. (PubMed:8710852)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62676 Genomic DNA. Translation: AAC44369.1.
AE004437 Genomic DNA. Translation: AAG19989.1.
PIRiA84328.
T44946.
RefSeqiNP_280509.1. NC_002607.1.

Genome annotation databases

EnsemblBacteriaiAAG19989; AAG19989; VNG_1765G.
GeneIDi1448291.
KEGGihal:VNG1765G.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62676 Genomic DNA. Translation: AAC44369.1 .
AE004437 Genomic DNA. Translation: AAG19989.1 .
PIRi A84328.
T44946.
RefSeqi NP_280509.1. NC_002607.1.

3D structure databases

ProteinModelPortali Q9HP81.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 64091.VNG1765G.

Proteomic databases

PaxDbi Q9HP81.
PRIDEi Q9HP81.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG19989 ; AAG19989 ; VNG_1765G .
GeneIDi 1448291.
KEGGi hal:VNG1765G.

Phylogenomic databases

eggNOGi COG0840.
InParanoidi Q9HP81.
OMAi IVEQTNM.
PhylomeDBi Q9HP81.

Family and domain databases

InterProi IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view ]
Pfami PF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view ]
SMARTi SM00304. HAMP. 2 hits.
SM00283. MA. 1 hit.
[Graphical view ]
PROSITEi PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The primary structures of the Archaeon Halobacterium salinarium blue light receptor sensory rhodopsin II and its transducer, a methyl-accepting protein."
    Zhang W., Brooun A., Mueller M.M., Alam M.
    Proc. Natl. Acad. Sci. U.S.A. 93:8230-8235(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Flx15.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700922 / JCM 11081 / NRC-1.
  3. "Sensory rhodopsin II transducer HtrII is also responsible for serine chemotaxis in the archaeon Halobacterium salinarum."
    Hou S., Brooun A., Yu H.S., Freitas T., Alam M.
    J. Bacteriol. 180:1600-1602(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiHTR2_HALSA
AccessioniPrimary (citable) accession number: Q9HP81
Secondary accession number(s): P71410
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3