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Q9HNQ6

- G6PI_HALSA

UniProt

Q9HNQ6 - G6PI_HALSA

Protein

Probable glucose-6-phosphate isomerase

Gene

pgi

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei272 – 2721Proton donorBy similarity
    Active sitei293 – 2931By similarity
    Active sitei404 – 4041By similarity

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glucose-6-phosphate isomerase (EC:5.3.1.9)
    Short name:
    GPI
    Alternative name(s):
    Phosphoglucose isomerase
    Short name:
    PGI
    Phosphohexose isomerase
    Short name:
    PHI
    Gene namesi
    Name:pgi
    Ordered Locus Names:VNG_1992G
    OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
    Taxonomic identifieri64091 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
    ProteomesiUP000000554: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 426426Probable glucose-6-phosphate isomerasePRO_0000180779Add
    BLAST

    Proteomic databases

    PaxDbiQ9HNQ6.

    Interactioni

    Protein-protein interaction databases

    STRINGi64091.VNG1992G.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9HNQ6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.Curated

    Phylogenomic databases

    eggNOGiCOG0166.
    KOiK01810.
    OMAiRANDEHG.
    PhylomeDBiQ9HNQ6.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9HNQ6-1 [UniParc]FASTAAdd to Basket

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    MRIDIGAALD ATATPGVPPD ALDRLDDRVA HAHDRITAGM DGDEFGYAAL    50
    NLPRTVDVDA ITAAADAVAD ADTLVTVGIG GSALGAATLV DALGDDDLDY 100
    HALDNVDPAH VTRLLDRIDL STSAVHVVSR SGTTAETLAN FLVVRDAMDD 150
    AGVDWTARTL VTTGDDGPLR ALADTHDLPV LDAPRGVPGR FAALSTVALP 200
    AAAIAGVDVG ELVAGAADGR AALAGSLEDC SAYAYGATAY ALDQRGAGVN 250
    AMLPYAERLE TFAEWFAQLW AESLGKDGVG QTPARALGAT DQHSQLQLYR 300
    AGPRDKLVTM LRPASRPDCA IPEAELADID YLTGGDLGAL LDAEFEATAA 350
    SLAASGVPTV RVEVPAVDAR SVGRLLFDFE AACVLAGELY GVETFTQPAV 400
    EWGKNAAREL LRGEDPLPET ETHIVE 426
    Length:426
    Mass (Da):44,202
    Last modified:March 1, 2001 - v1
    Checksum:i00D4A2C5187D8672
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004437 Genomic DNA. Translation: AAG20164.1.
    PIRiH84349.
    RefSeqiNP_280684.1. NC_002607.1.
    WP_010903465.1. NC_002607.1.

    Genome annotation databases

    EnsemblBacteriaiAAG20164; AAG20164; VNG_1992G.
    GeneIDi1448467.
    KEGGihal:VNG1992G.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE004437 Genomic DNA. Translation: AAG20164.1 .
    PIRi H84349.
    RefSeqi NP_280684.1. NC_002607.1.
    WP_010903465.1. NC_002607.1.

    3D structure databases

    ProteinModelPortali Q9HNQ6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 64091.VNG1992G.

    Proteomic databases

    PaxDbi Q9HNQ6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG20164 ; AAG20164 ; VNG_1992G .
    GeneIDi 1448467.
    KEGGi hal:VNG1992G.

    Phylogenomic databases

    eggNOGi COG0166.
    KOi K01810.
    OMAi RANDEHG.
    PhylomeDBi Q9HNQ6.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700922 / JCM 11081 / NRC-1.

    Entry informationi

    Entry nameiG6PI_HALSA
    AccessioniPrimary (citable) accession number: Q9HNQ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 2, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3