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Q9HNI2

- GLNA_HALSA

UniProt

Q9HNI2 - GLNA_HALSA

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Protein
Glutamine synthetase
Gene
glnA, VNG_2093G
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Enzyme regulationi

The activity of this enzyme is controlled by adenylation under conditions of abundant glutamine. The fully adenylated enzyme complex is inactive By similarity.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
  2. nitrogen fixation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Short name:
GS
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:glnA
Ordered Locus Names:VNG_2093G
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
ProteomesiUP000000554: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 454454Glutamine synthetase
PRO_0000153202Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei383 – 3831O-AMP-tyrosine By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9HNI2.
PRIDEiQ9HNI2.

Interactioni

Protein-protein interaction databases

STRINGi64091.VNG2093G.

Structurei

3D structure databases

ProteinModelPortaliQ9HNI2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0174.
KOiK01915.
OMAiWSGPNRS.
PhylomeDBiQ9HNI2.

Family and domain databases

Gene3Di3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
TIGRFAMsiTIGR00653. GlnA. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HNI2-1 [UniParc]FASTAAdd to Basket

« Hide

MTNGDSSSSA LTDNERAVLD DIEAQGIDFL RLQFTDILGT VKNVSIPAHQ    50
AEKAFTEGIY FDGSSIEGFV RIQESDMRLD PDPETFAVLP WRSNGDGGSA 100
RLICDVVDRE GNAFAGGPRQ VLKNVLARAD DMGYSVSIGP EPEFFLFEKD 150
DDGNATTTAH DQGGYFDLAP KDLASDIRRE IIFTLEAMGF EIEASHHEVA 200
RGQHEINFKY DDALTTADNI ATFRAVVRAV AEQHDVHATF MPKPIGEING 250
SGMHSHISLF DEDGENVFAD NDDEFNLSET AYQFMGGVLE HAPAFTAVTN 300
PTVNSYKRLV PGYEAPVYIA WSGVNRSALI RVPDAAGVSA RFEIRSPDPS 350
CNPYLALAAV IAAGLDGIDT DADPGDAVRE DIYEFDEDKR DAYGIDTLPG 400
HLGDAVTALE SDPVMQDALG EHVCEKFAEA KRHEYAEYKA SVSEWETDRY 450
LEKF 454
Length:454
Mass (Da):49,757
Last modified:March 1, 2001 - v1
Checksum:i09C12E8D0B91D538
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004437 Genomic DNA. Translation: AAG20238.1.
PIRiB84359.
RefSeqiNP_280758.1. NC_002607.1.

Genome annotation databases

EnsemblBacteriaiAAG20238; AAG20238; VNG_2093G.
GeneIDi1448542.
KEGGihal:VNG2093G.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004437 Genomic DNA. Translation: AAG20238.1 .
PIRi B84359.
RefSeqi NP_280758.1. NC_002607.1.

3D structure databases

ProteinModelPortali Q9HNI2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 64091.VNG2093G.

Proteomic databases

PaxDbi Q9HNI2.
PRIDEi Q9HNI2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG20238 ; AAG20238 ; VNG_2093G .
GeneIDi 1448542.
KEGGi hal:VNG2093G.

Phylogenomic databases

eggNOGi COG0174.
KOi K01915.
OMAi WSGPNRS.
PhylomeDBi Q9HNI2.

Family and domain databases

Gene3Di 3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
TIGRFAMsi TIGR00653. GlnA. 1 hit.
PROSITEi PS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700922 / JCM 11081 / NRC-1.

Entry informationi

Entry nameiGLNA_HALSA
AccessioniPrimary (citable) accession number: Q9HNI2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: March 1, 2001
Last modified: September 3, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi