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Q9HN46 (PSD_HALSA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:VNG_2255C
OrganismHalobacterium salinarium (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifier64091 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length225 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 192192Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029821
Chain193 – 22533Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029822

Sites

Site192 – 1932Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1931Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9HN46 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: CBDAADDD29879B62

FASTA22524,125
        10         20         30         40         50         60 
MLARVCERTP ISTPAWTDTL TRLAPDASSV LARGPWTWKY ALPPAVVGVA ALAASSPWGV 

        70         80         90        100        110        120 
VGVALAAFVV WFHRDPDRSP NGAGVVVPAD GTVSVIRTRD DGRVRVGVFM NVHNVHVNRV 

       130        140        150        160        170        180 
PVAGRVESVV HEPGGHRPAF SKESAHNERV RIETAEWTVV LIAGAFARRI HPYVEAGEDL 

       190        200        210        220 
ARGDRLGHIS FGSRADVVLP PAYDRGDVVV ESGQTVRAGE TVLAR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004437 Genomic DNA. Translation: AAG20375.1.
PIRC84376.
RefSeqNP_280895.1. NC_002607.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1448677.
GenomeReviewsGene locus VNG_2255C in contig AE004437_GR.
KEGGhal:VNG2255C.
NMPDRfig|64091.1.peg.1921.

Phylogenomic databases

HOGENOMHBG541103.
OMANERVVWH.
PhylomeDBQ9HN46.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycHSP64091:VNG2255C-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePSD_HALSA
AccessionPrimary (citable) accession number: Q9HN46
Entry history
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: March 1, 2001
Last modified: December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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