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Q9HN43

- CAPPA_HALSA

UniProt

Q9HN43 - CAPPA_HALSA

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppcA, VNG_2259C
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylase (EC:4.1.1.31)
Short name:
PEPC
Short name:
PEPCase
Gene namesi
Name:ppcA
Ordered Locus Names:VNG_2259C
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
ProteomesiUP000000554: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 492492Phosphoenolpyruvate carboxylaseUniRule annotation
PRO_0000309599Add
BLAST

Proteomic databases

PaxDbiQ9HN43.
PRIDEiQ9HN43.

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi64091.VNG2259C.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.

Phylogenomic databases

eggNOGiCOG1892.
KOiK01595.
OMAiKTMSTQH.
PhylomeDBiQ9HN43.

Family and domain databases

Gene3Di3.20.20.60. 1 hit.
HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HN43-1 [UniParc]FASTAAdd to Basket

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MVDVPRLMST QHPDNATLPF FTAGDVIEGE DEIQEAYYVY SHLGCDEQMW    50
DFEGKEGDEY AVKKLLSRYD EFFADHQLGT DVRLTVRGPN PDVEGSEAKI 100
LLEILESIPR SFDAARRFAG EYGLETTAPI FEVIVPMVTD ADQLNAVHEY 150
YERFVTGKAD EAVWDGRTVE EWVGEFDPAS ITVIPLIEER EAMLAADDIV 200
REYATAHDQD AVRVFLARSD PALNYGCLAA DLINKVALQR LYEMSEATGV 250
DVHPILGAGS APFRGNLTPE RAAATADAYS EVETFTVQSA FKYDYPVETV 300
RDGVATLRDA DLGAPPFPID EARALAVIDR TADAYADQVD AIAGTVNRLS 350
SYVPDRRARK LHVGLFGYAR EVGENALPRA IGYTASLYAV GCPPTLLGAH 400
ALTDDDAAFV REAFPAYFDH LADAARYFNP RCTDVLDLDD DTLAAAVERV 450
DVTPNSEHRA ATDDAIDALQ RGDDDALRSA IRRGARERQF LG 492
Length:492
Mass (Da):54,179
Last modified:March 1, 2001 - v1
Checksum:i12FBE025EF21C6D2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004437 Genomic DNA. Translation: AAG20378.1.
PIRiF84376.
RefSeqiNP_280898.1. NC_002607.1.

Genome annotation databases

EnsemblBacteriaiAAG20378; AAG20378; VNG_2259C.
GeneIDi1448680.
KEGGihal:VNG2259C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004437 Genomic DNA. Translation: AAG20378.1 .
PIRi F84376.
RefSeqi NP_280898.1. NC_002607.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 64091.VNG2259C.

Proteomic databases

PaxDbi Q9HN43.
PRIDEi Q9HN43.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG20378 ; AAG20378 ; VNG_2259C .
GeneIDi 1448680.
KEGGi hal:VNG2259C.

Phylogenomic databases

eggNOGi COG1892.
KOi K01595.
OMAi KTMSTQH.
PhylomeDBi Q9HN43.

Family and domain databases

Gene3Di 3.20.20.60. 1 hit.
HAMAPi MF_01904. PEPcase_type2.
InterProi IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF14010. PEPcase_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006677. UCP006677. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700922 / JCM 11081 / NRC-1.

Entry informationi

Entry nameiCAPPA_HALSA
AccessioniPrimary (citable) accession number: Q9HN43
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: March 1, 2001
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi