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Q9HN43 (CAPPA_HALSA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppcA
Ordered Locus Names:VNG_2259C
OrganismHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) [Reference proteome] [HAMAP]
Taxonomic identifier64091 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01904

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01904

Sequence similarities

Belongs to the PEPCase type 2 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 492492Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904
PRO_0000309599

Sequences

Sequence LengthMass (Da)Tools
Q9HN43 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 12FBE025EF21C6D2

FASTA49254,179
        10         20         30         40         50         60 
MVDVPRLMST QHPDNATLPF FTAGDVIEGE DEIQEAYYVY SHLGCDEQMW DFEGKEGDEY 

        70         80         90        100        110        120 
AVKKLLSRYD EFFADHQLGT DVRLTVRGPN PDVEGSEAKI LLEILESIPR SFDAARRFAG 

       130        140        150        160        170        180 
EYGLETTAPI FEVIVPMVTD ADQLNAVHEY YERFVTGKAD EAVWDGRTVE EWVGEFDPAS 

       190        200        210        220        230        240 
ITVIPLIEER EAMLAADDIV REYATAHDQD AVRVFLARSD PALNYGCLAA DLINKVALQR 

       250        260        270        280        290        300 
LYEMSEATGV DVHPILGAGS APFRGNLTPE RAAATADAYS EVETFTVQSA FKYDYPVETV 

       310        320        330        340        350        360 
RDGVATLRDA DLGAPPFPID EARALAVIDR TADAYADQVD AIAGTVNRLS SYVPDRRARK 

       370        380        390        400        410        420 
LHVGLFGYAR EVGENALPRA IGYTASLYAV GCPPTLLGAH ALTDDDAAFV REAFPAYFDH 

       430        440        450        460        470        480 
LADAARYFNP RCTDVLDLDD DTLAAAVERV DVTPNSEHRA ATDDAIDALQ RGDDDALRSA 

       490 
IRRGARERQF LG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004437 Genomic DNA. Translation: AAG20378.1.
PIRF84376.
RefSeqNP_280898.1. NC_002607.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING64091.VNG2259C.

Proteomic databases

PaxDbQ9HN43.
PRIDEQ9HN43.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG20378; AAG20378; VNG_2259C.
GeneID1448680.
KEGGhal:VNG2259C.

Phylogenomic databases

eggNOGCOG1892.
KOK01595.
OMAKTMSTQH.
PhylomeDBQ9HN43.

Family and domain databases

Gene3D3.20.20.60. 1 hit.
HAMAPMF_01904. PEPcase_type2.
InterProIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. SSF51621. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCAPPA_HALSA
AccessionPrimary (citable) accession number: Q9HN43
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: March 1, 2001
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families