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Q9HMZ1 (Q9HMZ1_HALSA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515
EC=4.2.1.24 RuleBase RU000515
Gene names
Name:hem2 EMBL AAG20430.1
Ordered Locus Names:VNG_2322G EMBL AAG20430.1
OrganismHalobacterium salinarium (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifier64091 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515

Subunit structure

Homooctamer By similarity. RuleBase RU000515 PIRSR PIRSR001415-3

Sequence similarities

Belongs to the ALADH family. RuleBase RU004161

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1991Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2521Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding1171Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1191Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1271Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding2371Magnesium By similarity PIRSR PIRSR001415-5
Binding site2091Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2211Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2781Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3171Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
Q9HMZ1 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: A9E6CDCDE3482060

FASTA32635,384
        10         20         30         40         50         60 
MELPHRPRRL RRDGVRDLVS ETMLTPADLV APVFVDATAD ERTPIPSMPG QERVPLADAV 

        70         80         90        100        110        120 
DRTREILDTG VEAIVLFGIP ASKDDTGSRA YADDGIVQEA TRRITSETDA YVITDVCLCE 

       130        140        150        160        170        180 
YTSHGHCGVV EADADTDPTL TVKNDETLSL LAETAVSHAE AGAEMIAPSA MTDGMVDAIR 

       190        200        210        220        230        240 
TALDDAGFSD VPIMSYAAKY ESAFYGPFRD AADGAPSFGD RRHYQMDPAN RREASREVAL 

       250        260        270        280        290        300 
DVEQGADVLM VKPALPYLDV VSDVRREFDR PVAAYNVSGE YAMLHAAAEK GWLDLESVAH 

       310        320 
ESLLSIKRAG ADLIITYFAE DVAETL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004437 Genomic DNA. Translation: AAG20430.1.
PIRB84383.
RefSeqNP_280950.1. NC_002607.1.

3D structure databases

HSSPHSSP built from PDB template 1PV8 based on UniProtKB P13716.
ProteinModelPortalQ9HMZ1.
SMRQ9HMZ1. Positions 5-326.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1448732.
GenomeReviewsGene locus VNG_2322G in contig AE004437_GR.
KEGGhal:VNG2322G.
NMPDRfig|64091.1.peg.1977.

Phylogenomic databases

HOGENOMHBG285270.
OMAADLCFCE.
PhylomeDBQ9HMZ1.
ProtClustDBPRK09283.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01698.
PANTHERPTHR11458. AlaD_dehydratase. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9HMZ1_HALSA
AccessionPrimary (citable) accession number: Q9HMZ1
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info