Q9HM64 (VATB_THEAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type ATP synthase beta chain

Alternative name(s):
V-ATPase subunit B

Gene names

Name:	atpB
Ordered Locus Names:	Ta0005

Organism

Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

Taxonomic identifier

273075 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length	460 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. HAMAP MF_00310
Sequence similarities	Belongs to the ATPase alpha/beta chains family.
Sequence caution	The sequence CAC11154.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	proton-transporting two-sector ATPase complex, catalytic domain Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 460	460	V-type ATP synthase beta chain HAMAP MF_00310		PRO_0000144669

Sequences

	Sequence		Length	Mass (Da)
	Q9HM64 [UniParc]. Last modified January 24, 2001. Version 1. Checksum: C5F8EE4E53DA393E	FASTA	460	51,006
	10 20 30 40 50 60 MPKLAYKSVS QISGPLLFVE NVPNAAYNEM VDIELENGET RQGQVLDTRK GLAIVQIFGA 70 80 90 100 110 120 TTGIGTQGTT VKFRGETARL PISEDMLGRV FNGIGEPIDG GPEIIAKERM EITSNAINPY 130 140 150 160 170 180 SREEPSEFIE TGISAIDGMN TLVRGQKLPI FSGSGLPHNQ LAAQIARQAK VLDSSENFAV 190 200 210 220 230 240 VFGAMGITSE EANYFTNQFR ETGALSRSVM FLNLSSDPSM ERIILPRIAL TTAEYLAFQK 250 260 270 280 290 300 GMHILVILTD MTNYCEALRE ISAAREEVPG RRGYPGYMYT DLSTIYERAG KLKGNNGSIT 310 320 330 340 350 360 QIPILTMPGD DITHPVPDLT GYITEGQIVI SRDLNRKDMY PGIDVLLSLS RLMNQGIGKG 370 380 390 400 410 420 RTREDHRGLA DQLYAAYASG KDLRSLTAIV GEEALSQNDR KYLHFADTFE SRYIKQGFFE 430 440 450 460 DRSIEDTLGL GWDLLADLPV QDMKRVKPDH IQKYGRWKKE

References

[1]	"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum." Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W. Nature 407:508-513(2000) [PubMed: 11029001] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL445063 Genomic DNA. Translation: CAC11154.1. Different initiation.
RefSeq	NP_393483.1. NC_002578.1.
3D structure databases
ProteinModelPortal	Q9HM64.
SMR	Q9HM64. Positions 14-454.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-7260650.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1455677.
GenomeReviews	Gene locus Ta0005 in contig AL139299_GR.
KEGG	tac:Ta0005.
NMPDR	fig|273075.1.peg.5.
Phylogenomic databases
HOGENOM	HBG565875.
OMA	VVFINLA.
PhylomeDB	Q9HM64.
ProtClustDB	PRK04196.
Enzyme and pathway databases
BioCyc	TACI273075:TA0005-MONOMER.
Family and domain databases
HAMAP	MF_00310. ATP_synth_B_arch. [Tree]
InterPro	IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C. IPR004100. ATPase_F1/V1/A1-cplx_a/bsu_N. IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd. IPR024034. ATPase_F1_bsu/V1_C. IPR022879. V-ATPase_su_B/beta. [Graphical view]
Gene3D	G3DSA:1.10.1140.10. G3DSA:1.10.1140.10. 1 hit.
KO	K02118.
Pfam	PF00006. ATP-synt_ab. 1 hit. PF00306. ATP-synt_ab_C. 1 hit. PF02874. ATP-synt_ab_N. 1 hit. [Graphical view]
SUPFAM	SSF47917. ATPase_a/b_C. 1 hit.
PROSITE	PS00152. ATPASE_ALPHA_BETA. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VATB_THEAC

Accession

Primary (citable) accession number: Q9HM64

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	January 24, 2001
Last modified:	December 14, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program