Q9HM59 (Q9HM59_THEAC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981

Gene names

Ordered Locus Names:

Ta0010

Organism

Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

Taxonomic identifier

273075 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. RuleBase RU003981
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981
Sequence similarities	Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase RuleBase RU003981 Methyltransferase EMBL CAC11159.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycine catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9HM59 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 1B4C3305B27F1F49	FASTA	336	37,454
	10 20 30 40 50 60 MPLYYRSIIE EHMAVRKHVG IFDVSHMGDV TVSGKDASAF LDHMFPTKVS NLKNGECVYT 70 80 90 100 110 120 AFLNDSGLMI DDTIVYRMGE DSYFFVPNAG TTEKIYRWVS DHSAGYSVKI ENVSNRISSI 130 140 150 160 170 180 ALQGPESEEV LNELGFSYPG YFKFQYVSGK YMNAITGKDQ IIISGTGYTG EKGVEFIIPN 190 200 210 220 230 240 EHAVELWKKL LEAINKRNGL PAGLGARDTL RMEKGMLLSG HDFNEDRDPY EASVSFIVNN 250 260 270 280 290 300 DEDFVGKKNL EIRRRSDHEI FRGFVLSDGI PRNGNPIKAG GKRVGTVTSG TISPVLNKGI 310 320 330 ALGYIDKAYS KENTEVMIEI RSVDHKAVVT KPRIVK

References

[1]

"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum." Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W. Nature 407:508-513(2000) [PubMed: 11029001] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL445063 Genomic DNA. Translation: CAC11159.1.
RefSeq	NP_393488.1. NC_002578.1.
3D structure databases
ProteinModelPortal	Q9HM59.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1456956.
GenomeReviews	Gene locus Ta0010 in contig AL139299_GR.
NMPDR	fig|273075.1.peg.10.
Phylogenomic databases
HOGENOM	HBG299834.
OMA	KALYGGM.
PhylomeDB	Q9HM59.
ProtClustDB	CLSK227987.
Enzyme and pathway databases
BioCyc	TACI273075:TA0010-MONOMER.
Family and domain databases
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9HM59_THEAC

Accession

Primary (citable) accession number: Q9HM59

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)