Q9HM16 (IF6_THEAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor 6
Short name=aIF-6

Gene names

Name:	eif6
Ordered Locus Names:	Ta0055

Organism

Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) [Reference proteome] [HAMAP]

Taxonomic identifier

273075 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma › Thermoplasma acidophilum

Protein attributes

Sequence length	216 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex By similarity. HAMAP-Rule MF_00032
Sequence similarities	Belongs to the eIF-6 family.
Sequence caution	The sequence CAC11203.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Initiation factor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mature ribosome assembly Inferred from electronic annotation. Source: InterPro
Molecular_function	ribosome binding Inferred from electronic annotation. Source: InterPro translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 216	216	Translation initiation factor 6 HAMAP-Rule MF_00032		PRO_0000153761

Sequences

	Sequence		Length	Mass (Da)
	Q9HM16 [UniParc]. Last modified April 3, 2002. Version 2. Checksum: 605A7971BE5B2357	FASTA	216	23,505
	10 20 30 40 50 60 MIRKTSVLRS NFIGIYAKAW DDVAFITMMA DEKTVADFQE VLQVDVRRIS IDNSSLIGTM 70 80 90 100 110 120 MVMNSNGLIV PYGSEITGLG DLDGRNVLQL KDKINAIGND IIANDHGAII HKNFSNRSRK 130 140 150 160 170 180 EIEDTLGVET IRTTIGNILT VGSAGILTSK GMLVNPETDD DELEFLRDFF KVSVKSGTAN 190 200 210 FGSIYVGASI VANSKGVLVG KDTTPIEMDR IDDVLS

References

[1]

"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum." Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W. Nature 407:508-513(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL445063 Genomic DNA. Translation: CAC11203.1. Different initiation.
RefSeq	NP_393534.1. NC_002578.1.
3D structure databases
ProteinModelPortal	Q9HM16.
ModBase	Search...
Protein-protein interaction databases
STRING	273075.Ta0055m.
Proteomic databases
PRIDE	Q9HM16.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAC11203; CAC11203; CAC11203.
GeneID	1456963.
KEGG	tac:Ta0055m.
Phylogenomic databases
eggNOG	COG1976.
KO	K03264.
OMA	QFENSNE.
ProtClustDB	PRK04046.
Family and domain databases
HAMAP	MF_00032. eIF-6.
InterPro	IPR002769. eIF6. [Graphical view]
PANTHER	PTHR10784. PTHR10784. 1 hit.
Pfam	PF01912. eIF-6. 1 hit. [Graphical view]
PIRSF	PIRSF006413. IF-6. 1 hit.
SMART	SM00654. eIF6. 1 hit. [Graphical view]
TIGRFAMs	TIGR00323. eIF-6. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IF6_THEAC

Accession

Primary (citable) accession number: Q9HM16

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2002
Last sequence update:	April 3, 2002
Last modified:	May 1, 2013
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program