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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTACI273075:G1GT7-298-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Ta0281
OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomic identifieri273075 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
Proteomesi
  • UP000001024 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516581 – 546Arginine--tRNA ligaseAdd BLAST546

Interactioni

Protein-protein interaction databases

STRINGi273075.Ta0281

Structurei

3D structure databases

ProteinModelPortaliQ9HLE7
SMRiQ9HLE7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi117 – 127"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00487 Archaea
COG0018 LUCA
HOGENOMiHOG000247213
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG093Z013U

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit

Sequencei

Sequence statusi: Complete.

Q9HLE7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLFQDLRKD IYEIVSKRFR ISENDVYLDD TGHSDITIRV FRILKSPDGG
60 70 80 90 100
ENAVMEIVRS ISEKDYVEKA LSEGGYINVW IKRTYMLREV LESIEKSGTY
110 120 130 140 150
PDVFQEAERV SVEHTSANPT GPLHIGRARN SIIGDSIYRI LSRYGYRTVR
160 170 180 190 200
QYFVNDSGKQ MISLYTAYIK YGGPITIENL LENYQKIYRE MEKDQSIEKE
210 220 230 240 250
IEKNIERYEN ADPEVFGTLR KIAGVMLDGI ASTLKRIGIE FDEFDWESDL
260 270 280 290 300
LLNGSVRKAI DMLETKEEDS ARYIEISGKK VFLTRKDGTT LYFARDIAYH
310 320 330 340 350
LFKAENSEWI IDVLGEDHKD HAKSLNHVLK EMLKLENRVS FMYYSFITLE
360 370 380 390 400
TGKMSTRRGN IVTLQDLVDR TYDEALKIVN EKRPDLSEEE RKKIAEVIAS
410 420 430 440 450
SAVRYSIIRV SAPKPITFRW EEALNFESNS APFIMYSHAR AASILDKAPE
460 470 480 490 500
PEQSYGMDMP KEEADLVKAM YVYPYYLKDA AQDLKPDLIA AYLISLVQKF
510 520 530 540
NDFYGACRVI GTDPLTYARR IRIVKAYKQI LSDAGDLIGI KMLDQM
Length:546
Mass (Da):63,004
Last modified:March 1, 2001 - v1
Checksum:iEB72B6D59406E078
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445063 Genomic DNA Translation: CAC11426.1
RefSeqiWP_010900710.1, NC_002578.1

Genome annotation databases

EnsemblBacteriaiCAC11426; CAC11426; CAC11426
GeneIDi1455910
KEGGitac:Ta0281

Similar proteinsi

Entry informationi

Entry nameiSYR_THEAC
AccessioniPrimary (citable) accession number: Q9HLE7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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