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Q9HLE7

- SYR_THEAC

UniProt

Q9HLE7 - SYR_THEAC

Protein

Arginine--tRNA ligase

Gene

argS

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

    GO - Molecular functioni

    1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
    2. ATP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
    Alternative name(s):
    Arginyl-tRNA synthetaseUniRule annotation
    Short name:
    ArgRSUniRule annotation
    Gene namesi
    Name:argSUniRule annotation
    Ordered Locus Names:Ta0281
    OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
    Taxonomic identifieri273075 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
    ProteomesiUP000001024: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 546546Arginine--tRNA ligasePRO_0000151658Add
    BLAST

    Proteomic databases

    PRIDEiQ9HLE7.

    Interactioni

    Protein-protein interaction databases

    STRINGi273075.Ta0281.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9HLE7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi117 – 12711"HIGH" regionAdd
    BLAST

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0018.
    HOGENOMiHOG000247213.
    KOiK01887.
    OMAiMEHMGFG.

    Family and domain databases

    Gene3Di1.10.730.10. 1 hit.
    3.40.50.620. 1 hit.
    HAMAPiMF_00123. Arg_tRNA_synth.
    InterProiIPR001278. Arg-tRNA-ligase.
    IPR008909. DALR_anticod-bd.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    [Graphical view]
    PANTHERiPTHR11956. PTHR11956. 1 hit.
    PfamiPF05746. DALR_1. 1 hit.
    PF00750. tRNA-synt_1d. 1 hit.
    [Graphical view]
    PRINTSiPR01038. TRNASYNTHARG.
    SMARTiSM00836. DALR_1. 1 hit.
    [Graphical view]
    SUPFAMiSSF47323. SSF47323. 1 hit.
    TIGRFAMsiTIGR00456. argS. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9HLE7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLFQDLRKD IYEIVSKRFR ISENDVYLDD TGHSDITIRV FRILKSPDGG    50
    ENAVMEIVRS ISEKDYVEKA LSEGGYINVW IKRTYMLREV LESIEKSGTY 100
    PDVFQEAERV SVEHTSANPT GPLHIGRARN SIIGDSIYRI LSRYGYRTVR 150
    QYFVNDSGKQ MISLYTAYIK YGGPITIENL LENYQKIYRE MEKDQSIEKE 200
    IEKNIERYEN ADPEVFGTLR KIAGVMLDGI ASTLKRIGIE FDEFDWESDL 250
    LLNGSVRKAI DMLETKEEDS ARYIEISGKK VFLTRKDGTT LYFARDIAYH 300
    LFKAENSEWI IDVLGEDHKD HAKSLNHVLK EMLKLENRVS FMYYSFITLE 350
    TGKMSTRRGN IVTLQDLVDR TYDEALKIVN EKRPDLSEEE RKKIAEVIAS 400
    SAVRYSIIRV SAPKPITFRW EEALNFESNS APFIMYSHAR AASILDKAPE 450
    PEQSYGMDMP KEEADLVKAM YVYPYYLKDA AQDLKPDLIA AYLISLVQKF 500
    NDFYGACRVI GTDPLTYARR IRIVKAYKQI LSDAGDLIGI KMLDQM 546
    Length:546
    Mass (Da):63,004
    Last modified:March 1, 2001 - v1
    Checksum:iEB72B6D59406E078
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL445063 Genomic DNA. Translation: CAC11426.1.
    RefSeqiNP_393761.1. NC_002578.1.
    WP_010900710.1. NC_002578.1.

    Genome annotation databases

    EnsemblBacteriaiCAC11426; CAC11426; CAC11426.
    GeneIDi1455910.
    KEGGitac:Ta0281.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL445063 Genomic DNA. Translation: CAC11426.1 .
    RefSeqi NP_393761.1. NC_002578.1.
    WP_010900710.1. NC_002578.1.

    3D structure databases

    ProteinModelPortali Q9HLE7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 273075.Ta0281.

    Proteomic databases

    PRIDEi Q9HLE7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC11426 ; CAC11426 ; CAC11426 .
    GeneIDi 1455910.
    KEGGi tac:Ta0281.

    Phylogenomic databases

    eggNOGi COG0018.
    HOGENOMi HOG000247213.
    KOi K01887.
    OMAi MEHMGFG.

    Family and domain databases

    Gene3Di 1.10.730.10. 1 hit.
    3.40.50.620. 1 hit.
    HAMAPi MF_00123. Arg_tRNA_synth.
    InterProi IPR001278. Arg-tRNA-ligase.
    IPR008909. DALR_anticod-bd.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    [Graphical view ]
    PANTHERi PTHR11956. PTHR11956. 1 hit.
    Pfami PF05746. DALR_1. 1 hit.
    PF00750. tRNA-synt_1d. 1 hit.
    [Graphical view ]
    PRINTSi PR01038. TRNASYNTHARG.
    SMARTi SM00836. DALR_1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47323. SSF47323. 1 hit.
    TIGRFAMsi TIGR00456. argS. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum."
      Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.
      Nature 407:508-513(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

    Entry informationi

    Entry nameiSYR_THEAC
    AccessioniPrimary (citable) accession number: Q9HLE7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 2003
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3