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Q9HLA7 (IF2G_THEAC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor 2 subunit gamma
Alternative name(s):
aIF2-gamma
eIF-2-gamma
Gene names
Name:eif2g
Ordered Locus Names:Ta0322
OrganismThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) [Reference proteome] [HAMAP]
Taxonomic identifier273075 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma

Protein attributes

Sequence length411 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA By similarity. HAMAP-Rule MF_00119

Subunit structure

Heterotrimer composed of an alpha, a beta and a gamma chain By similarity.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EIF2G subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 411411Translation initiation factor 2 subunit gamma HAMAP-Rule MF_00119
PRO_0000137465

Regions

Nucleotide binding18 – 258GTP By similarity
Nucleotide binding88 – 925GTP By similarity
Nucleotide binding144 – 1474GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9HLA7 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: CD27B96869210EC9

FASTA41144,859
        10         20         30         40         50         60 
MISKLKMPQP SVNIGMVGHV DHGKSTLTLA LTGTKTDTHS EEIKRGISIK LGYADTPIYR 

        70         80         90        100        110        120 
CYDSSGNVHY TREKGENCDL ERVISIVDAP GHETLMATML SGSALMNGAL LVIAANEHCP 

       130        140        150        160        170        180 
QPQTREHLTA LEIMGIKNII IVQNKIDLVT RERAIESYRE IKNFVKGSIA ENAPIIPVSA 

       190        200        210        220        230        240 
YHSTNIDALF EAIEKYIPSP KFNENDDPIM YIARSFDINR PGTPVSELKG GVIGGSLTQG 

       250        260        270        280        290        300 
EFALGDEIEI VPGIQTTKGN KTVWNNVTTE VVSLMAGKYS YDRIRPGGLA AIGTKLDPFL 

       310        320        330        340        350        360 
TKGDAFTGRI AGHVGKVPPV AFSMRLESHL LKRVVGSDQE LNVEPIRPKE TLMFTVATAN 

       370        380        390        400        410 
TVGVVNAMKG SEIEVSLKYP VAAFNGMRVA IGRRVMNRWR LIGYGIIQSL E 

« Hide

References

[1]"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum."
Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.
Nature 407:508-513(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL445063 Genomic DNA. Translation: CAC11467.1.
RefSeqNP_393802.1. NC_002578.1.

3D structure databases

ProteinModelPortalQ9HLA7.
SMRQ9HLA7. Positions 9-408.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273075.Ta0322.

Proteomic databases

PRIDEQ9HLA7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC11467; CAC11467; CAC11467.
GeneID1455943.
KEGGtac:Ta0322.

Phylogenomic databases

eggNOGCOG5257.
HOGENOMHOG000229292.
KOK03242.
OMAYRSDKED.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00119. eIF_2_gamma.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR022424. TIF2_gsu.
IPR015256. TIF2_gsu_C.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
[Graphical view]
PfamPF09173. eIF2_C. 1 hit.
PF00009. GTP_EFTU. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR03680. eif2g_arch. 1 hit.
TIGR00231. small_GTP. 1 hit.
ProtoNetSearch...

Entry information

Entry nameIF2G_THEAC
AccessionPrimary (citable) accession number: Q9HLA7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: March 1, 2001
Last modified: May 14, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries