Q9HL68 (Q9HL68_THEAC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aspartate-semialdehyde dehydrogenase related protein EMBL CAC11507.1

Gene names

Ordered Locus Names:

Ta0363

Organism

Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

Taxonomic identifier

273075 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aspartate-semialdehyde dehydrogenase family. RuleBase RU004041

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	isoleucine biosynthetic process Inferred from electronic annotation. Source: InterPro lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro methionine biosynthetic process Inferred from electronic annotation. Source: InterPro threonine biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: InterPro NAD binding Inferred from electronic annotation. Source: InterPro NADP binding Inferred from electronic annotation. Source: InterPro aspartate-semialdehyde dehydrogenase activity Inferred from electronic annotation. Source: InterPro protein dimerization activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	141	1	Acyl-thioester intermediate By similarity PIRSR PIRSR000148-1

Sequences

	Sequence		Length	Mass (Da)
	Q9HL68 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 8A1513F821460398	FASTA	338	36,528
	10 20 30 40 50 60 MDKLRVGLLG STGVVGSLLS KMIAIHPYFD LANVYASDRS AGQRYGNVVY GGASDLYRNL 70 80 90 100 110 120 EVKESNPDRI ISDHNDIIFS AVSDEKAGLI ERRLAEAGLP IFTNASANRL EDDVFLIVPE 130 140 150 160 170 180 INGDLVGSIK RKGFIIANGN CSTIGLALGI DPVIRGRSAV KIIVTTMQAV SGAGYPGVSS 190 200 210 220 230 240 LDIIDNMIPY IQKEETKIER ETKKIFSGKL DTEIFATTTR VPVKIGHMES VHIEFDQVLD 250 260 270 280 290 300 PSEIRAEFRS YGNGLLKTVY PSLPDRSVIL LEKDDRPQPA LDATNGGSAL KAGMAVSVGR 310 320 330 LRVRSRSLDL VLLVNNLVRG AAGSTLLNAE IAYKEGII

References

[1]

"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum." Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W. Nature 407:508-513(2000) [PubMed: 11029001] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL445064 Genomic DNA. Translation: CAC11507.1.
RefSeq	NP_393842.1. NC_002578.1.
3D structure databases
ProteinModelPortal	Q9HL68.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1455979.
GenomeReviews	Gene locus Ta0363 in contig AL139299_GR.
KEGG	tac:Ta0363.
NMPDR	fig|273075.1.peg.364.
Phylogenomic databases
HOGENOM	HBG518238.
OMA	GAGYNGV.
PhylomeDB	Q9HL68.
ProtClustDB	PRK08664.
Enzyme and pathway databases
BioCyc	TACI273075:TA0363-MONOMER.
Family and domain databases
InterPro	IPR005676. Asp_semi-ald_DH_pep-lack. IPR012080. Asp_semialdehyde_DH. IPR016040. NAD(P)-bd_dom. IPR000534. Semialdehyde_DH_NAD-bd. IPR012280. Semialdhyde_DH_dimer_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00133.
Pfam	PF01118. Semialdhyde_dh. 1 hit. PF02774. Semialdhyde_dhC. 1 hit. [Graphical view]
PIRSF	PIRSF000148. ASA_dh. 1 hit.
SMART	SM00859. Semialdhyde_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR00978. Asd_EA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9HL68_THEAC

Accession

Primary (citable) accession number: Q9HL68

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)