Reviewed, UniProtKB/Swiss-Prot Q9HL27 (APGM_THEAC)

Names and origin

Protein names

Recommended name:
    2,3-bisphosphoglycerate-independent phosphoglycerate mutase
      Short name=Phosphoglyceromutase
      Short name=BPG-independent PGAM
      Short name=aPGAM
    EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Ta0413

Organism

Thermoplasma acidophilum [Complete proteome] [HAMAP]

Taxonomic identifier

2303 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 404	404	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402		PRO_0000138150

Sequences

	Sequence		Length	Mass (Da)
	Q9HL27-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 06C0306580FE8BDF	FASTA	404	43,933
	10 20 30 40 50 60 MMKSIILIVL DGLGDRPGSD LQNRTPLQAA FRPNLNWLAS HGINGIMHPI SPGIRCGSDT 70 80 90 100 110 120 SHMSLLGYDP KVYYPGRGPF EALGLGMDIR PGDLAFRANF ATNRDGVIVD RRAGRENKGN 130 140 150 160 170 180 EELADAISLD MGEYSFRVKS GVEHRAALVV SGPDLSDMIG DSDPHREGLP PEKIRPTDPS 190 200 210 220 230 240 GDRTAEVMNA YLEEARRILS DHRVNKERVK NGRLPGNELL VRSAGKVPAI PSFTEKNRMK 250 260 270 280 290 300 GACVVGSPWL KGLCRLLRMD VFDVPGATGT VGSNYRGKIE KAVDLTSSHD FVLVNIKATD 310 320 330 340 350 360 VAGHDGNYPL KRDVIEDIDR AMEPLKSIGD HAVICVTGDH STPCSFKDHS GDPVPIVFYT 370 380 390 400 DGVMNDGVHL FDELSSASGS LRITSYNVMD ILMQLAGRSD KFGS

References

[1]

"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum." Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W. Nature 407:508-513(2000) [PubMed: 11029001] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25905 / AMRC-C165 / DSM 1728 / IFO 15155 / JCM 9062.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL445064 Genomic DNA. Translation: CAC11555.1.
RefSeq	NP_393891.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1456023.
GenomeReviews	Gene locus Ta0413 in contig AL139299_GR.
KEGG	tac:Ta0413.
NMPDR	fig|273075.1.peg.413.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9HL27.
OMA	ITGDHST.
Enzyme and pathway databases
BioCyc	TACI273075:TA0413-MON.
BRENDA	5.4.2.1. 435.
Family and domain databases
HAMAP	MF_01402. [Tree]
InterPro	IPR004456. APGAM_arc. IPR019304. bisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
ProDom	PD004704. APGAM_DeoB. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00306. apgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_THEAC

Accession

Primary (citable) accession number: Q9HL27

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2002
Last sequence update:	March 1, 2001
Last modified:	November 3, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)