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Q9HL27 (APGM_THEAC) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1
Gene names
Name:apgM
Ordered Locus Names:Ta0413
OrganismThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomic identifier273075 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length404 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A

Sequence similarities

Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
   Biological processGlycolysis
   Molecular functionIsomerase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: InterPro

phosphoglycerate mutase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4044042,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A
PRO_0000138150

Secondary structure

1 ...................................................... 404
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9HL27 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 06C0306580FE8BDF

FASTA40443,933
        10         20         30         40         50         60 
MMKSIILIVL DGLGDRPGSD LQNRTPLQAA FRPNLNWLAS HGINGIMHPI SPGIRCGSDT 

        70         80         90        100        110        120 
SHMSLLGYDP KVYYPGRGPF EALGLGMDIR PGDLAFRANF ATNRDGVIVD RRAGRENKGN 

       130        140        150        160        170        180 
EELADAISLD MGEYSFRVKS GVEHRAALVV SGPDLSDMIG DSDPHREGLP PEKIRPTDPS 

       190        200        210        220        230        240 
GDRTAEVMNA YLEEARRILS DHRVNKERVK NGRLPGNELL VRSAGKVPAI PSFTEKNRMK 

       250        260        270        280        290        300 
GACVVGSPWL KGLCRLLRMD VFDVPGATGT VGSNYRGKIE KAVDLTSSHD FVLVNIKATD 

       310        320        330        340        350        360 
VAGHDGNYPL KRDVIEDIDR AMEPLKSIGD HAVICVTGDH STPCSFKDHS GDPVPIVFYT 

       370        380        390        400 
DGVMNDGVHL FDELSSASGS LRITSYNVMD ILMQLAGRSD KFGS

« Hide

References

[1]"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum."
Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.
Nature 407:508-513(2000) [PubMed: 11029001] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL445064 Genomic DNA. Translation: CAC11555.1.
RefSeqNP_393891.1. NC_002578.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3IDDX-ray2.80A/B1-404[»]
3KD8X-ray2.60A/B2-397[»]
ProteinModelPortalQ9HL27.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1456023.
GenomeReviewsGene locus Ta0413 in contig AL139299_GR.
KEGGtac:Ta0413.
NMPDRfig|273075.1.peg.413.

Phylogenomic databases

HOGENOMHBG463247.
OMADIAFRCN.
ProtClustDBPRK04024.

Enzyme and pathway databases

BioCycTACI273075:TA0413-MONOMER.

Family and domain databases

HAMAPMF_01402_A. ApgM_A.
[Tree]
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR023665. ApgAM.
IPR004456. BisP-indep_Pglycerate_Mutase.
IPR006124. Metalloenzyme.
[Graphical view]
Gene3DG3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KOK15635.
PfamPF01676. Metalloenzyme. 1 hit.
PF10143. PhosphMutase. 1 hit.
[Graphical view]
PIRSFPIRSF006392. IPGAM_arch. 1 hit.
SUPFAMSSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMsTIGR00306. ApgM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPGM_THEAC
AccessionPrimary (citable) accession number: Q9HL27
Entry history
Integrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: March 1, 2001
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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