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Q9HKK0

- DCD_THEAC

UniProt

Q9HKK0 - DCD_THEAC

Protein

Probable deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 2 (27 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    dCTP + H2O = dUTP + NH3.

    Pathwayi

    GO - Molecular functioni

    1. dCTP deaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. dUMP biosynthetic process Source: UniProtKB-UniPathway
    2. dUTP biosynthetic process Source: InterPro
    3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Nucleotide metabolism

    Enzyme and pathway databases

    UniPathwayiUPA00610; UER00665.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable deoxycytidine triphosphate deaminase (EC:3.5.4.13)
    Short name:
    dCTP deaminase
    Gene namesi
    Name:dcd
    Ordered Locus Names:Ta0598
    OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
    Taxonomic identifieri273075 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
    ProteomesiUP000001024: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 166166Probable deoxycytidine triphosphate deaminasePRO_0000156042Add
    BLAST

    Proteomic databases

    PRIDEiQ9HKK0.

    Interactioni

    Protein-protein interaction databases

    STRINGi273075.Ta0598m.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9HKK0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the dCTP deaminase family.Curated

    Phylogenomic databases

    eggNOGiCOG0717.
    KOiK01494.
    OMAiFARKGIF.

    Family and domain databases

    Gene3Di2.70.40.10. 1 hit.
    HAMAPiMF_00146. dCTP_deaminase.
    InterProiIPR011962. dCTP_deam.
    IPR029054. dUTPase-like.
    IPR008180. dUTPase/dCTP_deaminase.
    [Graphical view]
    PfamiPF00692. dUTPase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51283. SSF51283. 1 hit.
    TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9HKK0-1 [UniParc]FASTAAdd to Basket

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    MILNDSTIMR MVSDGLLISE NFDRGCLTPN GYDLRVDAID VEGRQYSEFE    50
    IGKNVHFLVS TIEILKIPDD VVGMIWTRSS FARKGIFGSF GAIDAGYHGN 100
    LTLSFFNAGS AVNLRRGERI AQIVFVKMIG SAEKPYHIRS GNYQNSRGIV 150
    KDPVAGSQIA SEAKKN 166
    Length:166
    Mass (Da):18,293
    Last modified:March 27, 2002 - v2
    Checksum:i1F4C9467CA3BFBD8
    GO

    Sequence cautioni

    The sequence CAC11737.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL445064 Genomic DNA. Translation: CAC11737.1. Different initiation.
    RefSeqiNP_394071.1. NC_002578.1.

    Genome annotation databases

    EnsemblBacteriaiCAC11737; CAC11737; CAC11737.
    GeneIDi1457022.
    KEGGitac:Ta0598m.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL445064 Genomic DNA. Translation: CAC11737.1 . Different initiation.
    RefSeqi NP_394071.1. NC_002578.1.

    3D structure databases

    ProteinModelPortali Q9HKK0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 273075.Ta0598m.

    Proteomic databases

    PRIDEi Q9HKK0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC11737 ; CAC11737 ; CAC11737 .
    GeneIDi 1457022.
    KEGGi tac:Ta0598m.

    Phylogenomic databases

    eggNOGi COG0717.
    KOi K01494.
    OMAi FARKGIF.

    Enzyme and pathway databases

    UniPathwayi UPA00610 ; UER00665 .

    Family and domain databases

    Gene3Di 2.70.40.10. 1 hit.
    HAMAPi MF_00146. dCTP_deaminase.
    InterProi IPR011962. dCTP_deam.
    IPR029054. dUTPase-like.
    IPR008180. dUTPase/dCTP_deaminase.
    [Graphical view ]
    Pfami PF00692. dUTPase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51283. SSF51283. 1 hit.
    TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum."
      Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.
      Nature 407:508-513(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

    Entry informationi

    Entry nameiDCD_THEAC
    AccessioniPrimary (citable) accession number: Q9HKK0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 27, 2001
    Last sequence update: March 27, 2002
    Last modified: October 1, 2014
    This is version 78 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3