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Q9HKK0

- DCD_THEAC

UniProt

Q9HKK0 - DCD_THEAC

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Protein

Probable deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable deoxycytidine triphosphate deaminase (EC:3.5.4.13)
Short name:
dCTP deaminase
Gene namesi
Name:dcd
Ordered Locus Names:Ta0598
OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomic identifieri273075 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
ProteomesiUP000001024: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 166166Probable deoxycytidine triphosphate deaminasePRO_0000156042Add
BLAST

Proteomic databases

PRIDEiQ9HKK0.

Interactioni

Protein-protein interaction databases

STRINGi273075.Ta0598m.

Structurei

3D structure databases

ProteinModelPortaliQ9HKK0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.Curated

Phylogenomic databases

eggNOGiCOG0717.
KOiK01494.
OMAiFARKGIF.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HKK0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MILNDSTIMR MVSDGLLISE NFDRGCLTPN GYDLRVDAID VEGRQYSEFE
60 70 80 90 100
IGKNVHFLVS TIEILKIPDD VVGMIWTRSS FARKGIFGSF GAIDAGYHGN
110 120 130 140 150
LTLSFFNAGS AVNLRRGERI AQIVFVKMIG SAEKPYHIRS GNYQNSRGIV
160
KDPVAGSQIA SEAKKN
Length:166
Mass (Da):18,293
Last modified:March 27, 2002 - v2
Checksum:i1F4C9467CA3BFBD8
GO

Sequence cautioni

The sequence CAC11737.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445064 Genomic DNA. Translation: CAC11737.1. Different initiation.
RefSeqiNP_394071.1. NC_002578.1.

Genome annotation databases

EnsemblBacteriaiCAC11737; CAC11737; CAC11737.
GeneIDi1457022.
KEGGitac:Ta0598m.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445064 Genomic DNA. Translation: CAC11737.1 . Different initiation.
RefSeqi NP_394071.1. NC_002578.1.

3D structure databases

ProteinModelPortali Q9HKK0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273075.Ta0598m.

Proteomic databases

PRIDEi Q9HKK0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC11737 ; CAC11737 ; CAC11737 .
GeneIDi 1457022.
KEGGi tac:Ta0598m.

Phylogenomic databases

eggNOGi COG0717.
KOi K01494.
OMAi FARKGIF.

Enzyme and pathway databases

UniPathwayi UPA00610 ; UER00665 .

Family and domain databases

Gene3Di 2.70.40.10. 1 hit.
HAMAPi MF_00146. dCTP_deaminase.
InterProi IPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view ]
Pfami PF00692. dUTPase. 1 hit.
[Graphical view ]
SUPFAMi SSF51283. SSF51283. 1 hit.
TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum."
    Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.
    Nature 407:508-513(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

Entry informationi

Entry nameiDCD_THEAC
AccessioniPrimary (citable) accession number: Q9HKK0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: March 27, 2002
Last modified: October 1, 2014
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3