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Q9HK30 (PDAD_THEAC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyruvoyl-dependent arginine decarboxylase

Short name=PvlArgDC
EC=4.1.1.19
Gene names
Name:pdaD
Ordered Locus Names:Ta0778
OrganismThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) [Reference proteome] [HAMAP]
Taxonomic identifier273075 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma

Protein attributes

Sequence length182 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01404

Cofactor

Pyruvoyl group By similarity. HAMAP-Rule MF_01404

Sequence similarities

Belongs to the PdaD family.

Sequence caution

The sequence CAC11909.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginine catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionarginine decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4343Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity
PRO_0000023336
Chain44 – 182139Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity
PRO_0000023337

Sites

Site43 – 442Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue441Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9HK30 [UniParc].

Last modified July 11, 2002. Version 2.
Checksum: 2053EE343EE41B89

FASTA18219,672
        10         20         30         40         50         60 
MSGFVPTHIF FTRGVGRGET QLVSFEAALR DAGIAPYNLS SISSIFPPHA EMITREEGLK 

        70         80         90        100        110        120 
KLSPGQILFT VLARNTSNEL NRMVSAAIGY AIPRDRSKWG YLSEHHSFGE TEKVAGSFAE 

       130        140        150        160        170        180 
KLAAEMLAST IGSSAQLAYD KQKEEYVLED KILTTGSISS TAVVLESGEW TTVVAAAVLI 


VE 

« Hide

References

[1]"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum."
Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.
Nature 407:508-513(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL445065 Genomic DNA. Translation: CAC11909.1. Different initiation.
RefSeqNP_394240.1. NC_002578.1.

3D structure databases

ProteinModelPortalQ9HK30.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273075.Ta0778.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC11909; CAC11909; CAC11909.
GeneID1456332.
KEGGtac:Ta0778.

Phylogenomic databases

eggNOGCOG1945.
HOGENOMHOG000012204.
KOK02626.
OMASEHHSFG.
ProtClustDBPRK01285.

Family and domain databases

Gene3D3.50.20.10. 1 hit.
HAMAPMF_01404. PvlArgDC.
InterProIPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view]
PfamPF01862. PvlArgDC. 1 hit.
[Graphical view]
PIRSFPIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomPD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56271. SSF56271. 1 hit.
TIGRFAMsTIGR00286. TIGR00286. 1 hit.
ProtoNetSearch...

Entry information

Entry namePDAD_THEAC
AccessionPrimary (citable) accession number: Q9HK30
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: July 11, 2002
Last modified: February 19, 2014
This is version 65 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families