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Protein

Nucleoside-triphosphatase THEP1

Gene

Ta0998

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.UniRule annotation

Catalytic activityi

NTP + H2O = NDP + phosphate.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19ATPUniRule annotation8
Nucleotide bindingi104 – 111ATPUniRule annotation8

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTACI273075:G13HZ-1005-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside-triphosphatase THEP1UniRule annotation (EC:3.6.1.15UniRule annotation)
Short name:
NTPase THEP1UniRule annotation
Alternative name(s):
Nucleoside triphosphate phosphohydrolaseUniRule annotation
Gene namesi
Ordered Locus Names:Ta0998
OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomic identifieri273075 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
Proteomesi
  • UP000001024 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001467071 – 181Nucleoside-triphosphatase THEP1Add BLAST181

Proteomic databases

PRIDEiQ9HJH0.

Interactioni

Protein-protein interaction databases

STRINGi273075.Ta0998.

Structurei

3D structure databases

ProteinModelPortaliQ9HJH0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the THEP1 NTPase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01034. Archaea.
COG1618. LUCA.
HOGENOMiHOG000006446.
KOiK06928.
OMAiTIYMAYR.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00796. NTPase_1. 1 hit.
InterProiIPR004948. Nuc-triphosphatase_THEP1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF03266. NTPase_1. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HJH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPLAIKIGI TGPVGSIKSE ALQKIIDMLK NDNLNVQGVL VSKVTNNGKL
60 70 80 90 100
TGYTIEDIES KRKAQFCFDN FVSRVKIDKL GVDTKILEEI LIPSLQKARE
110 120 130 140 150
TADVIVIDEI GKLENTTKKV HAEIEETLKC GKPLIVTLHK RSRNPVLQEI
160 170 180
KSLEGVRVFD ITPINKNILP FKVMHVLKGE E
Length:181
Mass (Da):20,194
Last modified:March 1, 2001 - v1
Checksum:iC18742AB6FB99FAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445066 Genomic DNA. Translation: CAC12127.1.
RefSeqiWP_010901409.1. NC_002578.1.

Genome annotation databases

EnsemblBacteriaiCAC12127; CAC12127; CAC12127.
GeneIDi1456522.
KEGGitac:Ta0998.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445066 Genomic DNA. Translation: CAC12127.1.
RefSeqiWP_010901409.1. NC_002578.1.

3D structure databases

ProteinModelPortaliQ9HJH0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273075.Ta0998.

Proteomic databases

PRIDEiQ9HJH0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC12127; CAC12127; CAC12127.
GeneIDi1456522.
KEGGitac:Ta0998.

Phylogenomic databases

eggNOGiarCOG01034. Archaea.
COG1618. LUCA.
HOGENOMiHOG000006446.
KOiK06928.
OMAiTIYMAYR.

Enzyme and pathway databases

BioCyciTACI273075:G13HZ-1005-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00796. NTPase_1. 1 hit.
InterProiIPR004948. Nuc-triphosphatase_THEP1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF03266. NTPase_1. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNTPTH_THEAC
AccessioniPrimary (citable) accession number: Q9HJH0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.