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Protein

Cytidylate kinase

Gene

cmk

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (d)CMP = ADP + (d)CDP.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi7 – 159ATPBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytidylate kinase (EC:2.7.4.25)
Short name:
CK
Alternative name(s):
Cytidine monophosphate kinase
Short name:
CMP kinase
Gene namesi
Name:cmk
Ordered Locus Names:Ta1245
OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomic identifieri273075 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
Proteomesi
  • UP000001024 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 188188Cytidylate kinasePRO_0000132026Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273075.Ta1245.

Structurei

3D structure databases

ProteinModelPortaliQ9HIT3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG01037. Archaea.
COG1102. LUCA.
HOGENOMiHOG000105913.
KOiK00945.
OMAiFIFRDMA.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00239. Cytidyl_kinase_type2. 1 hit.
InterProiIPR026865. Cmk2-like.
IPR011892. Cyt_kin_arch.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13189. Cytidylate_kin2. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02173. cyt_kin_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9HIT3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRITIAGKIG SGKSTVSSEL SRITGYTVYS SGTFFRETAR KMNMSIEDFN
60 70 80 90 100
VYSESHPEAD YYTDETQKAF MQANDNIIVE GRLAGWISYL NGINAFRIFL
110 120 130 140 150
YATYYTRLVR FAGRENIDID SARDLMEKRE KSEKERYRKL YGIDVDDLSI
160 170 180
YDIVVNTEFM KPPEIAVYIA NRIDEMSRKD IFTPRILR
Length:188
Mass (Da):21,864
Last modified:March 1, 2001 - v1
Checksum:i5A1026B75EA9B035
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445067 Genomic DNA. Translation: CAC12369.1.
RefSeqiWP_010901652.1. NC_002578.1.

Genome annotation databases

EnsemblBacteriaiCAC12369; CAC12369; CAC12369.
GeneIDi1456736.
KEGGitac:Ta1245.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445067 Genomic DNA. Translation: CAC12369.1.
RefSeqiWP_010901652.1. NC_002578.1.

3D structure databases

ProteinModelPortaliQ9HIT3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273075.Ta1245.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC12369; CAC12369; CAC12369.
GeneIDi1456736.
KEGGitac:Ta1245.

Phylogenomic databases

eggNOGiarCOG01037. Archaea.
COG1102. LUCA.
HOGENOMiHOG000105913.
KOiK00945.
OMAiFIFRDMA.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00239. Cytidyl_kinase_type2. 1 hit.
InterProiIPR026865. Cmk2-like.
IPR011892. Cyt_kin_arch.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13189. Cytidylate_kin2. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02173. cyt_kin_arch. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKCY_THEAC
AccessioniPrimary (citable) accession number: Q9HIT3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: March 1, 2001
Last modified: November 11, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.