Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA-directed RNA polymerase subunit L

Gene

rpoL

Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.By similarity

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit L (EC:2.7.7.6)
Gene namesi
Name:rpoL
Ordered Locus Names:Ta1416
OrganismiThermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomic identifieri273075 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
Proteomesi
  • UP000001024 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 111111DNA-directed RNA polymerase subunit LPRO_0000149341Add
BLAST

Proteomic databases

PRIDEiQ9HIC5.

Interactioni

Protein-protein interaction databases

STRINGi273075.Ta1416.

Structurei

Secondary structure

1
111
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi10 – 167Combined sources
Beta strandi18 – 2710Combined sources
Helixi30 – 4011Combined sources
Beta strandi46 – 527Combined sources
Turni56 – 583Combined sources
Beta strandi62 – 709Combined sources
Helixi72 – 10433Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1XPPX-ray1.60A/B/C/D1-111[»]
ProteinModelPortaliQ9HIC5.
SMRiQ9HIC5. Positions 7-107.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9HIC5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG04111. Archaea.
COG1761. LUCA.
HOGENOMiHOG000179862.
KOiK03056.
OMAiVEMINYD.

Family and domain databases

HAMAPiMF_00261. RNApol_arch_L. 1 hit.
InterProiIPR009025. RBP11-like_dimer.
IPR008193. RNA_pol_Rpb11_13-16kDa_CS.
IPR022905. RNAP_L.
[Graphical view]
SUPFAMiSSF55257. SSF55257. 1 hit.
PROSITEiPS01154. RNA_POL_L_13KD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HIC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRERTAESS LRVISKEKNS ITVEMINYDN TLLRTLVEEI LKDDQVDEAR
60 70 80 90 100
YYIKHPVIDN PQIYVRVKSG KPQSAIKRAV RKLSKLYEDL GTQFQKEFQR
110
YESDHMIKAV E
Length:111
Mass (Da):13,133
Last modified:March 1, 2001 - v1
Checksum:i8EE9BE506B177F6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445067 Genomic DNA. Translation: CAC12536.1.
RefSeqiWP_010901819.1. NC_002578.1.

Genome annotation databases

EnsemblBacteriaiCAC12536; CAC12536; CAC12536.
GeneIDi1456876.
KEGGitac:Ta1416.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445067 Genomic DNA. Translation: CAC12536.1.
RefSeqiWP_010901819.1. NC_002578.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1XPPX-ray1.60A/B/C/D1-111[»]
ProteinModelPortaliQ9HIC5.
SMRiQ9HIC5. Positions 7-107.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273075.Ta1416.

Proteomic databases

PRIDEiQ9HIC5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC12536; CAC12536; CAC12536.
GeneIDi1456876.
KEGGitac:Ta1416.

Phylogenomic databases

eggNOGiarCOG04111. Archaea.
COG1761. LUCA.
HOGENOMiHOG000179862.
KOiK03056.
OMAiVEMINYD.

Miscellaneous databases

EvolutionaryTraceiQ9HIC5.

Family and domain databases

HAMAPiMF_00261. RNApol_arch_L. 1 hit.
InterProiIPR009025. RBP11-like_dimer.
IPR008193. RNA_pol_Rpb11_13-16kDa_CS.
IPR022905. RNAP_L.
[Graphical view]
SUPFAMiSSF55257. SSF55257. 1 hit.
PROSITEiPS01154. RNA_POL_L_13KD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPOL_THEAC
AccessioniPrimary (citable) accession number: Q9HIC5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: March 1, 2001
Last modified: November 11, 2015
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.