Reviewed, UniProtKB/Swiss-Prot Q9HIA9 (COMB_THEAC)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	Ta1432

Organism

Thermoplasma acidophilum [Complete proteome] [HAMAP]

Taxonomic identifier

2303 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 220	220	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081461

Sequences

	Sequence		Length	Mass (Da)
	Q9HIA9-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 1F9643CC4BCA7428	FASTA	220	24,654
	10 20 30 40 50 60 MIRIGDGRKS DSWAEINVVV DIFRSTTTIP MILFRGAKYI LPFRDVRKAI EFKRRNPGTI 70 80 90 100 110 120 LVGEKYGIKP PYFDYDNSPA EIAEADLSGK VVAFTSTNGT YVLSRIRSGR IIFSSYVNLS 130 140 150 160 170 180 ATVAMIRSQR DVLILPSNRP IGKAPEDILF ANLLKLMAEG HEVDVSEYTR KTEEINRNII 190 200 210 220 AGVGERDLEF CLRVDHTNIV PEYIDGRIVQ SPDSVALTDA

References

[1]

"The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum." Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W. Nature 407:508-513(2000) [PubMed: 11029001] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25905 / AMRC-C165 / DSM 1728 / IFO 15155 / JCM 9062.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL445067 Genomic DNA. Translation: CAC12552.1.
RefSeq	NP_394886.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1456888.
GenomeReviews	Gene locus Ta1432 in contig AL139299_GR.
KEGG	tac:Ta1432.
NMPDR	fig|273075.1.peg.1408.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9HIA9.
OMA	Q9HIA9. RSTTTIP.
Enzyme and pathway databases
BioCyc	TACI273075:TA1432-MON.
BRENDA	3.1.3.71. 435.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

COMB_THEAC

Accession

Primary (citable) accession number: Q9HIA9

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 5, 2001
Last sequence update:	March 1, 2001
Last modified:	May 5, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)