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Q9HHN2

- SYR_HALSA

UniProt

Q9HHN2 - SYR_HALSA

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Protein
Arginine--tRNA ligase
Gene
argS, VNG_6312G
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:VNG_6312G
Encoded oniPlasmid pNRC2000 Publication
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
ProteomesiUP000000554: Plasmid pNRC200

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 631631Arginine--tRNA ligaseUniRule annotation
PRO_0000151644Add
BLAST

Proteomic databases

PaxDbiQ9HHN2.
PRIDEiQ9HHN2.

Interactioni

Protein-protein interaction databases

STRINGi64091.VNG6312G.

Structurei

3D structure databases

ProteinModelPortaliQ9HHN2.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi132 – 14211"HIGH" regionUniRule annotation
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0018.
KOiK01887.
OMAiNFERNSA.
PhylomeDBiQ9HHN2.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HHN2-1 [UniParc]FASTAAdd to Basket

« Hide

MLYNLRQELL AGIRAATSDA GYDYEVDQSA IELEDITDEE KGEFSSPISF    50
SIAAAAGAPP VDVAAAIADA HRSNGLPAEV EAVTVEGGHI NYHADTTDLA 100
DATLSTILRD GSEYGTRTDA DPDTILADVS SPNIAKPLHV GHLRNTILSD 150
AVMNILEARG HDVTRDNHLG DWGVQFGNLM HEYTEFGDEA TLEDDAIEHL 200
LDLYQQFEQR DSMLADLEDD ETVTDQFADA VTEERDYHAD SGKEWFTRLE 250
QGDEDATALW ERFRTVSIDR FKQTYDDLDV AFDVWNGESF YAQEGWNDVI 300
IEKAIENDVA MRGEGESVYI PVYPDDYENV GDPQAADVDA SLDRARQMRE 350
ANDDLEDADF DPFYIVKSDG STLYGTRDLA TIEYRIEEYD ADQSVYVVAN 400
EQNQYFQQLF VAARKMGYND IKLKHIDYGL ISLPEGSMST RKGQIITARE 450
VLDRAQDRAE EIIAEKGRID DAEAQSVATK IALATIKYEM VAAKRERDTT 500
FDIDESVALE GDTGPYVQYA ATRGYSILDG ADAAPEIDDL DPSVFNDTDV 550
ELLFELARYP LVLERCEERY DAAPLAHYLL QLAHVFNSFY HKNAVLDAEN 600
ARTERLLLTK ATTQIFDNGL GLLGIDVLEE M 631
Length:631
Mass (Da):70,471
Last modified:March 1, 2001 - v1
Checksum:i1BF5F0A47AF1B30E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004438 Genomic DNA. Translation: AAG20944.1.
RefSeqiNP_395809.1. NC_002608.1.
WP_010904157.1. NC_002608.1.

Genome annotation databases

EnsemblBacteriaiAAG20944; AAG20944; VNG_6312G.
GeneIDi1449192.
KEGGihal:VNG6312G.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE004438 Genomic DNA. Translation: AAG20944.1 .
RefSeqi NP_395809.1. NC_002608.1.
WP_010904157.1. NC_002608.1.

3D structure databases

ProteinModelPortali Q9HHN2.
ModBasei Search...

Protein-protein interaction databases

STRINGi 64091.VNG6312G.

Proteomic databases

PaxDbi Q9HHN2.
PRIDEi Q9HHN2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG20944 ; AAG20944 ; VNG_6312G .
GeneIDi 1449192.
KEGGi hal:VNG6312G.

Phylogenomic databases

eggNOGi COG0018.
KOi K01887.
OMAi NFERNSA.
PhylomeDBi Q9HHN2.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700922 / JCM 11081 / NRC-1.

Entry informationi

Entry nameiSYR_HALSA
AccessioniPrimary (citable) accession number: Q9HHN2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: March 1, 2001
Last modified: September 3, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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