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Q9HHN2 (SYR_HALSA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:VNG_6312G
Encoded onPlasmid pNRC200
OrganismHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) [Reference proteome] [HAMAP]
Taxonomic identifier64091 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium

Protein attributes

Sequence length631 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Plasmid
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 631631Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151644

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q9HHN2 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 1BF5F0A47AF1B30E

FASTA63170,471
        10         20         30         40         50         60 
MLYNLRQELL AGIRAATSDA GYDYEVDQSA IELEDITDEE KGEFSSPISF SIAAAAGAPP 

        70         80         90        100        110        120 
VDVAAAIADA HRSNGLPAEV EAVTVEGGHI NYHADTTDLA DATLSTILRD GSEYGTRTDA 

       130        140        150        160        170        180 
DPDTILADVS SPNIAKPLHV GHLRNTILSD AVMNILEARG HDVTRDNHLG DWGVQFGNLM 

       190        200        210        220        230        240 
HEYTEFGDEA TLEDDAIEHL LDLYQQFEQR DSMLADLEDD ETVTDQFADA VTEERDYHAD 

       250        260        270        280        290        300 
SGKEWFTRLE QGDEDATALW ERFRTVSIDR FKQTYDDLDV AFDVWNGESF YAQEGWNDVI 

       310        320        330        340        350        360 
IEKAIENDVA MRGEGESVYI PVYPDDYENV GDPQAADVDA SLDRARQMRE ANDDLEDADF 

       370        380        390        400        410        420 
DPFYIVKSDG STLYGTRDLA TIEYRIEEYD ADQSVYVVAN EQNQYFQQLF VAARKMGYND 

       430        440        450        460        470        480 
IKLKHIDYGL ISLPEGSMST RKGQIITARE VLDRAQDRAE EIIAEKGRID DAEAQSVATK 

       490        500        510        520        530        540 
IALATIKYEM VAAKRERDTT FDIDESVALE GDTGPYVQYA ATRGYSILDG ADAAPEIDDL 

       550        560        570        580        590        600 
DPSVFNDTDV ELLFELARYP LVLERCEERY DAAPLAHYLL QLAHVFNSFY HKNAVLDAEN 

       610        620        630 
ARTERLLLTK ATTQIFDNGL GLLGIDVLEE M 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004438 Genomic DNA. Translation: AAG20944.1.
RefSeqNP_395809.1. NC_002608.1.

3D structure databases

ProteinModelPortalQ9HHN2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING64091.VNG6312G.

Proteomic databases

PaxDbQ9HHN2.
PRIDEQ9HHN2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG20944; AAG20944; VNG_6312G.
GeneID1449192.
KEGGhal:VNG6312G.

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMANFERNSA.
PhylomeDBQ9HHN2.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_HALSA
AccessionPrimary (citable) accession number: Q9HHN2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: March 1, 2001
Last modified: May 14, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries