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Q9HGZ2 (G6PI_ASPOR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgiA
ORF Names:AO090011000659
OrganismAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) [Complete proteome]
Taxonomic identifier510516 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length553 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 553553Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180571

Sites

Active site3631Proton donor By similarity
Active site3941 By similarity
Active site5161 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9HGZ2 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 06373377B1FF8949

FASTA55361,214
        10         20         30         40         50         60 
MPAFSQATDL SAWKELQEHH TAVGRNIVLK EAFEKDPQRF EKFSRTFKNT VDNSDILFDF 

        70         80         90        100        110        120 
SKNFLTEETL SLLVKLAKEA NVEELRDAMF KGEHINFTED RAVYHAALRN VSNEPMQVDG 

       130        140        150        160        170        180 
KSVVEDVNSV LEHMKEFSEQ VRSGEWKGYT DKKIDTIINI GIGGSDLGPV MVTEALKPYG 

       190        200        210        220        230        240 
APGMKLHFVS NIDGTHIAEA LKDSNPETTL FLIASKTFTT AETTTNANSA KKWFLETAKD 

       250        260        270        280        290        300 
ESHIAKHFVA LSTNEAEVTK FGIDKKNMFG FESWVGGRYS VWSAIGLSVA LYIGYDNFHQ 

       310        320        330        340        350        360 
FLAGAQAMDK HFREAPLEQN IPAIGGLLSV WYSDFFGAQT HLVAPFDQYL HRFPAYLQQL 

       370        380        390        400        410        420 
SMESNGKAIT RSGEYVKYTT GPILFGEPAT NAQHSFFQLL HQGTKLIPSD FIMAAESHNP 

       430        440        450        460        470        480 
VEGGKHQRML ASNFLAQSEA LMVGKTPEQV KTEGAPDNLV PHKTFLGNRP TTSILAQKIT 

       490        500        510        520        530        540 
PSTLGALIAY YEHLTFTEGA VWNINSFDQW GVELGKVLAK KIQQELETSG AGAGHDASTS 

       550 
GLLAAFKQKA NLA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB032269 mRNA. Translation: BAB12229.1.
AP007171 Genomic DNA. Translation: BAE65122.1.
RefSeqXP_001826255.1. XM_001826203.2.

3D structure databases

ProteinModelPortalQ9HGZ2.
SMRQ9HGZ2. Positions 5-550.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ9HGZ2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAORAT00005381; CADAORAP00005280; CADAORAG00005381.
GeneID5998358.
KEGGaor:AOR_1_1132054.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMALKMHFVS.
OrthoDBEOG7N0CDV.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_ASPOR
AccessionPrimary (citable) accession number: Q9HGZ2
Secondary accession number(s): Q2TZZ3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: March 1, 2001
Last modified: February 19, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways