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Q9HGY2 (GPD1_ZYGRO) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

EC=1.1.1.8
Alternative name(s):
ZrGPD1
Gene names
Name:GPD1
OrganismZygosaccharomyces rouxii (Candida mogii)
Taxonomic identifier4956 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeZygosaccharomyces

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Glycerol-3-phosphate dehydrogenase [NAD(+)] 1
PRO_0000138101

Regions

Nucleotide binding40 – 456NAD By similarity
Region309 – 3102Substrate binding By similarity

Sites

Active site2441Proton acceptor By similarity
Binding site1281NAD By similarity
Binding site1511NAD; via amide nitrogen By similarity
Binding site1511Substrate By similarity
Binding site1841NAD; via amide nitrogen By similarity
Binding site3091NAD By similarity
Binding site3381NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9HGY2 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: E698797A2AA20A16

FASTA40143,791
        10         20         30         40         50         60 
MAATDRLNQT SDILSQSMKK TDSSMSVVTA ENPYKVSVVG SGNWGTTIAK VVAENTKEKP 

        70         80         90        100        110        120 
ELFQERVDMW VFEEQIDGTP LAQIINTKHQ NVKYLPNIDL PDNLVANPDL IATTKDADVI 

       130        140        150        160        170        180 
VFNVPHQFLG RIVAQMKGQI KPTARAVSCL KGFEVGPKGV QLLSDYVTQE LGIECGALSG 

       190        200        210        220        230        240 
ANLAPEVAKE HWSETTVAYH IPDDFKGDGK DIDHRVLKQL FHRPYFHVNV IDDVAGISIA 

       250        260        270        280        290        300 
GALKNVVALG CGFVTGLGWG NNAAAAIQRV GLGEIIKFGR MFFPESKVET YYQESAGVAD 

       310        320        330        340        350        360 
LITTCSGGRN VRVATEMAKT GKSGEQVEKD ILNGQSAQGL VTCKEVHQWL ESSGNTEDFP 

       370        380        390        400 
LFEAVYQITY ENVPMKELPS MIEELDIDST SKCVLSYKMG L 

« Hide

References

[1]"Cloning of glycerol-3-phosphate dehydrogenase genes (ZrGPD1 and ZrGPD2) and glycerol dehydrogenase genes (ZrGCY1 and ZrGCY2) from the salt-tolerant yeast Zygosaccharomyces rouxii."
Iwaki T., Kurono S., Yokose Y., Kubota K., Tamai Y., Watanabe Y.
Yeast 18:737-744(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 42981 / IAM 12879 / JCM 22060 / S-96.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB047394 Genomic DNA. Translation: BAB11957.1.

3D structure databases

ProteinModelPortalQ9HGY2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. SSF48179. 1 hit.
TIGRFAMsTIGR03376. glycerol3P_DH. 1 hit.
PROSITEPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGPD1_ZYGRO
AccessionPrimary (citable) accession number: Q9HGY2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: March 1, 2001
Last modified: October 16, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families