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Q9HGY2

- GPD1_ZYGRO

UniProt

Q9HGY2 - GPD1_ZYGRO

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Protein
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1
Gene
GPD1
Organism
Zygosaccharomyces rouxii (Candida mogii)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei128 – 1281NAD By similarity
Binding sitei151 – 1511NAD; via amide nitrogen By similarity
Binding sitei151 – 1511Substrate By similarity
Binding sitei184 – 1841NAD; via amide nitrogen By similarity
Active sitei244 – 2441Proton acceptor By similarity
Binding sitei309 – 3091NAD By similarity
Binding sitei338 – 3381NAD By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi40 – 456NAD By similarity

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. glycerol-3-phosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 (EC:1.1.1.8)
Alternative name(s):
ZrGPD1
Gene namesi
Name:GPD1
OrganismiZygosaccharomyces rouxii (Candida mogii)
Taxonomic identifieri4956 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeZygosaccharomyces

Subcellular locationi

Cytoplasm Reviewed prediction

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 401401Glycerol-3-phosphate dehydrogenase [NAD(+)] 1
PRO_0000138101Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9HGY2.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni309 – 3102Substrate binding By similarity

Sequence similaritiesi

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HGY2-1 [UniParc]FASTAAdd to Basket

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MAATDRLNQT SDILSQSMKK TDSSMSVVTA ENPYKVSVVG SGNWGTTIAK    50
VVAENTKEKP ELFQERVDMW VFEEQIDGTP LAQIINTKHQ NVKYLPNIDL 100
PDNLVANPDL IATTKDADVI VFNVPHQFLG RIVAQMKGQI KPTARAVSCL 150
KGFEVGPKGV QLLSDYVTQE LGIECGALSG ANLAPEVAKE HWSETTVAYH 200
IPDDFKGDGK DIDHRVLKQL FHRPYFHVNV IDDVAGISIA GALKNVVALG 250
CGFVTGLGWG NNAAAAIQRV GLGEIIKFGR MFFPESKVET YYQESAGVAD 300
LITTCSGGRN VRVATEMAKT GKSGEQVEKD ILNGQSAQGL VTCKEVHQWL 350
ESSGNTEDFP LFEAVYQITY ENVPMKELPS MIEELDIDST SKCVLSYKMG 400
L 401
Length:401
Mass (Da):43,791
Last modified:March 1, 2001 - v1
Checksum:iE698797A2AA20A16
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB047394 Genomic DNA. Translation: BAB11957.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB047394 Genomic DNA. Translation: BAB11957.1 .

3D structure databases

ProteinModelPortali Q9HGY2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProi IPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PANTHERi PTHR11728. PTHR11728. 1 hit.
Pfami PF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSi PR00077. GPDHDRGNASE.
SUPFAMi SSF48179. SSF48179. 1 hit.
TIGRFAMsi TIGR03376. glycerol3P_DH. 1 hit.
PROSITEi PS00957. NAD_G3PDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning of glycerol-3-phosphate dehydrogenase genes (ZrGPD1 and ZrGPD2) and glycerol dehydrogenase genes (ZrGCY1 and ZrGCY2) from the salt-tolerant yeast Zygosaccharomyces rouxii."
    Iwaki T., Kurono S., Yokose Y., Kubota K., Tamai Y., Watanabe Y.
    Yeast 18:737-744(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 42981 / IAM 12879 / JCM 22060 / S-96.

Entry informationi

Entry nameiGPD1_ZYGRO
AccessioniPrimary (citable) accession number: Q9HGY2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: March 1, 2001
Last modified: October 16, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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