Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9HGY1

- GPD2_ZYGRO

UniProt

Q9HGY1 - GPD2_ZYGRO

Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)] 2

Gene

GPD2

Organism
Zygosaccharomyces rouxii (Candida mogii)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei128 – 1281NADBy similarity
    Binding sitei151 – 1511NAD; via amide nitrogenBy similarity
    Binding sitei151 – 1511SubstrateBy similarity
    Binding sitei184 – 1841NAD; via amide nitrogenBy similarity
    Active sitei244 – 2441Proton acceptorBy similarity
    Binding sitei309 – 3091NADBy similarity
    Binding sitei338 – 3381NADBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi40 – 456NADBy similarity

    GO - Molecular functioni

    1. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: UniProtKB-EC
    2. NAD binding Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro
    2. glycerol-3-phosphate catabolic process Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycerol-3-phosphate dehydrogenase [NAD(+)] 2 (EC:1.1.1.8)
    Alternative name(s):
    ZrGPD2
    Gene namesi
    Name:GPD2
    OrganismiZygosaccharomyces rouxii (Candida mogii)
    Taxonomic identifieri4956 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeZygosaccharomyces

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. glycerol-3-phosphate dehydrogenase complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 389389Glycerol-3-phosphate dehydrogenase [NAD(+)] 2PRO_0000138102Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ9HGY1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni309 – 3102Substrate bindingBy similarity

    Sequence similaritiesi

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR013328. DH_multihelical.
    IPR006168. G3P_DH_NAD-dep.
    IPR006109. G3P_DH_NAD-dep_C.
    IPR017751. G3P_DH_NAD-dep_euk.
    IPR011128. G3P_DH_NAD-dep_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR11728. PTHR11728. 1 hit.
    PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
    PF01210. NAD_Gly3P_dh_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
    PRINTSiPR00077. GPDHDRGNASE.
    SUPFAMiSSF48179. SSF48179. 1 hit.
    TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
    PROSITEiPS00957. NAD_G3PDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9HGY1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAATDRLNQT SDILSHSMKK TDTSMSIVTA ENPYKVAVVG SGNWGTTIAK    50
    VVAENTKEKP ELFQGRVDMW VFEEQIDGTP LTQIINTKHQ NVKYLPNIDL 100
    PGNLVANPDL ISTTKDADVI VFNVPHQFLG RIVSQMKGQI KPDARAISCL 150
    KGFEVGPKGV QLLSDYVTQE LGIQCGALSG ANLAPEVAKE HWSETTVAYQ 200
    VPDDFKGEGK DIDHRVLKQL FHRPYFHVNV IDDVAGISIA GALKNVVALG 250
    CGFVTGLGWG NNAAAAIQRV GLGEIIKFGR MFFPESKVET YYQESAGVAD 300
    LITTCSGGRN VRVATEMAKT GKSGEQVEKD ILNGQSAQGL ITAKEVHQWL 350
    ESSGHTEEYP LFEAVYQITY ENVPMKELPS MIEELDIVE 389
    Length:389
    Mass (Da):42,511
    Last modified:March 1, 2001 - v1
    Checksum:i70BBA9C2AAB463D0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB047395 mRNA. Translation: BAB11958.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB047395 mRNA. Translation: BAB11958.1 .

    3D structure databases

    ProteinModelPortali Q9HGY1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR013328. DH_multihelical.
    IPR006168. G3P_DH_NAD-dep.
    IPR006109. G3P_DH_NAD-dep_C.
    IPR017751. G3P_DH_NAD-dep_euk.
    IPR011128. G3P_DH_NAD-dep_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11728. PTHR11728. 1 hit.
    Pfami PF07479. NAD_Gly3P_dh_C. 1 hit.
    PF01210. NAD_Gly3P_dh_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000114. Glycerol-3-P_dh. 1 hit.
    PRINTSi PR00077. GPDHDRGNASE.
    SUPFAMi SSF48179. SSF48179. 1 hit.
    TIGRFAMsi TIGR03376. glycerol3P_DH. 1 hit.
    PROSITEi PS00957. NAD_G3PDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of glycerol-3-phosphate dehydrogenase genes (ZrGPD1 and ZrGPD2) and glycerol dehydrogenase genes (ZrGCY1 and ZrGCY2) from the salt-tolerant yeast Zygosaccharomyces rouxii."
      Iwaki T., Kurono S., Yokose Y., Kubota K., Tamai Y., Watanabe Y.
      Yeast 18:737-744(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: ATCC 42981 / IAM 12879 / JCM 22060 / S-96.

    Entry informationi

    Entry nameiGPD2_ZYGRO
    AccessioniPrimary (citable) accession number: Q9HGY1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3