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Q9HFW8 (TRPF_ZYGBA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:TRP1
OrganismZygosaccharomyces bailii
Taxonomic identifier4954 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeZygosaccharomyces

Protein attributes

Sequence length205 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
   Molecular functionIsomerase
Gene Ontology (GO)
   Biological_processtryptophan biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionphosphoribosylanthranilate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 205205N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154338

Sequences

Sequence LengthMass (Da)Tools
Q9HFW8 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: DECD9AE9F0DDBC0E

FASTA20522,316
        10         20         30         40         50         60 
MIAKICGLQS VEAAQQAVDN GADLIGVICV PNRKRTVDPE IARSISKICH GTGTRLVGVF 

        70         80         90        100        110        120 
RNQPKEEVRQ LAQEYELDVV QLHGDEDWQE YASYVGLPLL KRVVFPRDVS LVSQMDGEVC 

       130        140        150        160        170        180 
TPLFDSEAGG SGEKLDWQAI GSWFQDSQLT RGYLLAGGLS PDNVVEALRV PGVVGVDVSG 

       190        200 
GVETDGTKDL AKIKQFLELY KVNVN 

« Hide

References

[1]"Targeted gene deletion in Zygosaccharomyces bailii."
Mollapour M., Piper P.W.
Yeast 18:173-186(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: CBS 685 / NCYC 563 / NRRL Y-12949.
[2]"Sequence analyses of a Zygosaccharomyces bailii DNA fragment containing the Thr-tRNA, IPP1 and TRP1 genes."
Rodrigues F.J., Steensma Y., Corte-Real M.S.
Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ISA 1307.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF279262 Genomic DNA. Translation: AAG17697.1.
AJ309279 Genomic DNA. Translation: CAC37331.1.

3D structure databases

ProteinModelPortalQ9HFW8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_ZYGBA
AccessionPrimary (citable) accession number: Q9HFW8
Entry history
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways