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Q9HFV8 (PYRF_PASFU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Uridine 5'-monophosphate synthase
Short name=UMP synthase
Gene names
Name:PYR1
OrganismPassalora fulva (Tomato leaf mold) (Cladosporium fulvum)
Taxonomic identifier5499 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesDothideomycetidaeCapnodialesMycosphaerellaceaePassalora

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Orotidine 5'-phosphate = UMP + CO2.

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Sequence similarities

Belongs to the OMP decarboxylase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278Orotidine 5'-phosphate decarboxylase
PRO_0000134656

Regions

Region62 – 643Substrate binding By similarity
Region93 – 10210Substrate binding By similarity

Sites

Active site951Proton donor By similarity
Binding site401Substrate By similarity
Binding site2281Substrate By similarity
Binding site2461Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9HFV8 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 6DD0B6B102127C63

FASTA27829,957
        10         20         30         40         50         60 
MSSKSQLPFS TRASNHPNPL ARKLFEVAEA KKSNVTVSAD VTTTKELLDL ADRLGPYIAV 

        70         80         90        100        110        120 
IKTHIDILSD FGPETINGLN ALAEKHNFLI FEDRKFIDIG NTVQKQYHGG ALKISEWAHI 

       130        140        150        160        170        180 
INCAVLPAEG IVQALAETAQ AEDFPHGSER GLLILAEMTS KGSLATGEYT SASVDYARKY 

       190        200        210        220        230        240 
PSFVLGFVST RALTEVSSTV TAADNEDFVV FTTGVNLSSK GDKLGQQYQT PQSAIGRGAD 

       250        260        270 
FIIAGRGIYT APDPVEAAKQ YQQQGWEAYL ARVGGASQ 

« Hide

References

[1]"The pyr1 gene of the tomato pathogen Cladosporium fulvum."
Snoeijers S.S.
Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF288696 Genomic DNA. Translation: AAG10516.1.

3D structure databases

ProteinModelPortalQ9HFV8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR014732. OMPdecase.
IPR018089. OMPdecase_AS.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR01740. pyrF. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_PASFU
AccessionPrimary (citable) accession number: Q9HFV8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: March 1, 2001
Last modified: October 16, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways