Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9HF68 (PYRF_SOLCC) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Uridine 5'-monophosphate synthase
Short name=UMP synthase
Gene names
Name:PYRG
OrganismSolorina crocea
Taxonomic identifier48864 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaLecanoromycetesLecanoromycetidaePeltigeralesPeltigerineaePeltigeraceaeSolorina

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Orotidine 5'-phosphate = UMP + CO2.

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Sequence similarities

Belongs to the OMP decarboxylase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 280280Orotidine 5'-phosphate decarboxylase
PRO_0000134684

Regions

Region62 – 643Substrate binding By similarity
Region93 – 10210Substrate binding By similarity

Sites

Active site951Proton donor By similarity
Binding site401Substrate By similarity
Binding site2281Substrate By similarity
Binding site2461Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9HF68 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 163723FCA7B66ACC

FASTA28030,749
        10         20         30         40         50         60 
MTSKSTLSYA ERARQHDNPI ARKLFEIAEA KKSNVVVSAD LTTTKELLEL ADHLGPYIAV 

        70         80         90        100        110        120 
LKTHIDIVSD FNKETVFGLK SLSEKHNFLI FEDRKFVDIG NTVQKQYHGG ALRISEWAHL 

       130        140        150        160        170        180 
VNASILAGDG IVEALAQTGT SDAFEHKGER GLLMLAEMTT RGTFATGAYT KASIESAKKH 

       190        200        210        220        230        240 
SSFVIGFISN QALTSIETQI PATHMEDFIV FTTGVNRATK GDPLGQQYQT PEAAIKRGAD 

       250        260        270        280 
FIISGRGIYA TSDPIQAAKL YQNEGWAAYE TRIKNRSTGY 

« Hide

References

[1]"Cloning and heterologous expression of Solorina crocea pyrG."
Sinnemann S.J., Andresson O.S., Brown D.W., Miao V.P.
Curr. Genet. 37:333-338(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF206163 Genomic DNA. Translation: AAG34761.1.

3D structure databases

ProteinModelPortalQ9HF68.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR014732. OMPdecase.
IPR018089. OMPdecase_AS.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR01740. pyrF. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_SOLCC
AccessionPrimary (citable) accession number: Q9HF68
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: March 1, 2001
Last modified: October 16, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways