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Protein

GTP-binding protein ypt71

Gene

ypt71

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 228GTPBy similarity
Nucleotide bindingi63 – 675GTPBy similarity
Nucleotide bindingi124 – 1274GTPBy similarity

GO - Molecular functioni

  1. GDP binding Source: GO_Central
  2. GTPase activity Source: PomBase
  3. GTP binding Source: GO_Central

GO - Biological processi

  1. endocytosis Source: PomBase
  2. Golgi to vacuole transport Source: PomBase
  3. GTP catabolic process Source: GO_Central
  4. intracellular protein transport Source: GO_Central
  5. negative regulation of vacuole fusion, non-autophagic Source: PomBase
  6. phagosome-lysosome fusion Source: GO_Central
  7. Rab protein signal transduction Source: GO_Central
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GTP-binding protein ypt71
Gene namesi
Name:ypt71
ORF Names:SPAPB1A10.10c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAPB1A10.10c.

Subcellular locationi

Vacuole By similarity

GO - Cellular componenti

  1. cytosol Source: PomBase
  2. fungal-type vacuole membrane Source: GO_Central
  3. late endosome Source: GO_Central
  4. lysosome Source: GO_Central
  5. nucleus Source: PomBase
  6. phagocytic vesicle Source: GO_Central
  7. vacuolar membrane Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 208208GTP-binding protein ypt71PRO_0000121314Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi206 – 2061S-geranylgeranyl cysteineBy similarity
Modified residuei208 – 2081Cysteine methyl esterBy similarity
Lipidationi208 – 2081S-geranylgeranyl cysteineBy similarity

Keywords - PTMi

Lipoprotein, Methylation, Prenylation

Proteomic databases

MaxQBiQ9HDY0.
PRIDEiQ9HDY0.

Interactioni

Protein-protein interaction databases

BioGridi279833. 8 interactions.
MINTiMINT-4702725.
STRINGi4896.SPAPB1A10.10c-1.

Structurei

3D structure databases

ProteinModelPortaliQ9HDY0.
SMRiQ9HDY0. Positions 7-181.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi37 – 459Effector regionBy similarity

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiCOG1100.
HOGENOMiHOG000233968.
InParanoidiQ9HDY0.
KOiK07976.
OMAiCIANAAL.
OrthoDBiEOG7X0VTC.
PhylomeDBiQ9HDY0.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
PRINTSiPR00449. RASTRNSFRMNG.
SMARTiSM00175. RAB. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HDY0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSAQKRVFLK VVILGDSGVG KTCLMNQFVN QKFSREYKAT IGADFLTKDV
60 70 80 90 100
VVDDKLVTLQ LWDTAGQERF QSLGMAFYRG ADCCVIVYNV NNSKSFDSVE
110 120 130 140 150
NWRQEFLYQT SQDECAFPFI IVGNQIDKDA SKRAVSLHRA LDYCKSKHGS
160 170 180 190 200
NMIHFEASAK ENTNVTDLFE TVSRLALENE SSRDDFVNDF SEPLLLSKPL

NNTSSCNC
Length:208
Mass (Da):23,474
Last modified:March 1, 2001 - v1
Checksum:i9B76A6881BC4F389
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAC21483.1.
RefSeqiNP_593524.1. NM_001018958.2.

Genome annotation databases

EnsemblFungiiSPAPB1A10.10c.1; SPAPB1A10.10c.1:pep; SPAPB1A10.10c.
GeneIDi2543411.
KEGGispo:SPAPB1A10.10c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAC21483.1.
RefSeqiNP_593524.1. NM_001018958.2.

3D structure databases

ProteinModelPortaliQ9HDY0.
SMRiQ9HDY0. Positions 7-181.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279833. 8 interactions.
MINTiMINT-4702725.
STRINGi4896.SPAPB1A10.10c-1.

Proteomic databases

MaxQBiQ9HDY0.
PRIDEiQ9HDY0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAPB1A10.10c.1; SPAPB1A10.10c.1:pep; SPAPB1A10.10c.
GeneIDi2543411.
KEGGispo:SPAPB1A10.10c.

Organism-specific databases

PomBaseiSPAPB1A10.10c.

Phylogenomic databases

eggNOGiCOG1100.
HOGENOMiHOG000233968.
InParanoidiQ9HDY0.
KOiK07976.
OMAiCIANAAL.
OrthoDBiEOG7X0VTC.
PhylomeDBiQ9HDY0.

Miscellaneous databases

NextBioi20804426.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
PRINTSiPR00449. RASTRNSFRMNG.
SMARTiSM00175. RAB. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiYPT71_SCHPO
AccessioniPrimary (citable) accession number: Q9HDY0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: March 1, 2001
Last modified: February 4, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.