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Q9HDY0

- YPT71_SCHPO

UniProt

Q9HDY0 - YPT71_SCHPO

Protein

GTP-binding protein ypt71

Gene

ypt71

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi15 – 228GTPBy similarity
    Nucleotide bindingi63 – 675GTPBy similarity
    Nucleotide bindingi124 – 1274GTPBy similarity

    GO - Molecular functioni

    1. GTPase activity Source: PomBase
    2. GTP binding Source: UniProtKB-KW

    GO - Biological processi

    1. endocytosis Source: PomBase
    2. Golgi to vacuole transport Source: PomBase
    3. GTP catabolic process Source: GOC
    4. intracellular protein transport Source: PomBase
    5. negative regulation of vacuole fusion, non-autophagic Source: PomBase
    6. small GTPase mediated signal transduction Source: InterPro

    Keywords - Biological processi

    Protein transport, Transport

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTP-binding protein ypt71
    Gene namesi
    Name:ypt71
    ORF Names:SPAPB1A10.10c
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome I

    Organism-specific databases

    PomBaseiSPAPB1A10.10c.

    Subcellular locationi

    Vacuole By similarity

    GO - Cellular componenti

    1. cytosol Source: PomBase
    2. nucleus Source: PomBase
    3. vacuolar membrane Source: PomBase

    Keywords - Cellular componenti

    Vacuole

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 208208GTP-binding protein ypt71PRO_0000121314Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Lipidationi206 – 2061S-geranylgeranyl cysteineBy similarity
    Modified residuei208 – 2081Cysteine methyl esterBy similarity
    Lipidationi208 – 2081S-geranylgeranyl cysteineBy similarity

    Keywords - PTMi

    Lipoprotein, Methylation, Prenylation

    Proteomic databases

    MaxQBiQ9HDY0.
    PRIDEiQ9HDY0.

    Interactioni

    Protein-protein interaction databases

    BioGridi279833. 8 interactions.
    MINTiMINT-4702725.
    STRINGi4896.SPAPB1A10.10c-1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9HDY0.
    SMRiQ9HDY0. Positions 7-181.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi37 – 459Effector regionBy similarity

    Sequence similaritiesi

    Belongs to the small GTPase superfamily. Rab family.Curated

    Phylogenomic databases

    eggNOGiCOG1100.
    HOGENOMiHOG000233968.
    KOiK07976.
    OMAiCIANAAL.
    OrthoDBiEOG7X0VTC.
    PhylomeDBiQ9HDY0.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR003579. Small_GTPase_Rab_type.
    [Graphical view]
    PfamiPF00071. Ras. 1 hit.
    [Graphical view]
    PRINTSiPR00449. RASTRNSFRMNG.
    SMARTiSM00175. RAB. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00231. small_GTP. 1 hit.
    PROSITEiPS51419. RAB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9HDY0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAQKRVFLK VVILGDSGVG KTCLMNQFVN QKFSREYKAT IGADFLTKDV    50
    VVDDKLVTLQ LWDTAGQERF QSLGMAFYRG ADCCVIVYNV NNSKSFDSVE 100
    NWRQEFLYQT SQDECAFPFI IVGNQIDKDA SKRAVSLHRA LDYCKSKHGS 150
    NMIHFEASAK ENTNVTDLFE TVSRLALENE SSRDDFVNDF SEPLLLSKPL 200
    NNTSSCNC 208
    Length:208
    Mass (Da):23,474
    Last modified:March 1, 2001 - v1
    Checksum:i9B76A6881BC4F389
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAC21483.1.
    RefSeqiNP_593524.1. NM_001018958.2.

    Genome annotation databases

    EnsemblFungiiSPAPB1A10.10c.1; SPAPB1A10.10c.1:pep; SPAPB1A10.10c.
    GeneIDi2543411.
    KEGGispo:SPAPB1A10.10c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAC21483.1 .
    RefSeqi NP_593524.1. NM_001018958.2.

    3D structure databases

    ProteinModelPortali Q9HDY0.
    SMRi Q9HDY0. Positions 7-181.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 279833. 8 interactions.
    MINTi MINT-4702725.
    STRINGi 4896.SPAPB1A10.10c-1.

    Proteomic databases

    MaxQBi Q9HDY0.
    PRIDEi Q9HDY0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPAPB1A10.10c.1 ; SPAPB1A10.10c.1:pep ; SPAPB1A10.10c .
    GeneIDi 2543411.
    KEGGi spo:SPAPB1A10.10c.

    Organism-specific databases

    PomBasei SPAPB1A10.10c.

    Phylogenomic databases

    eggNOGi COG1100.
    HOGENOMi HOG000233968.
    KOi K07976.
    OMAi CIANAAL.
    OrthoDBi EOG7X0VTC.
    PhylomeDBi Q9HDY0.

    Miscellaneous databases

    NextBioi 20804426.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR003579. Small_GTPase_Rab_type.
    [Graphical view ]
    Pfami PF00071. Ras. 1 hit.
    [Graphical view ]
    PRINTSi PR00449. RASTRNSFRMNG.
    SMARTi SM00175. RAB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51419. RAB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.

    Entry informationi

    Entry nameiYPT71_SCHPO
    AccessioniPrimary (citable) accession number: Q9HDY0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 24, 2006
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3