Reviewed,
UniProtKB/Swiss-Prot Q9HDU5 (GAL7_SCHPO)
Last modified
February 9, 2010.
Version 63.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Galactose-1-phosphate uridylyltransferase Short name=Gal-1-P uridylyltransferase EC=2.7.7.12 Alternative name(s): UDP-glucose--hexose-1-phosphate uridylyltransferase | ||||
| Gene names |
| ||||
| Organism | Schizosaccharomyces pombe (Fission yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4896 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces |
Protein attributes
| Sequence length | 369 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. |
| Cofactor | Binds 1 iron ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity. |
| Pathway | |
| Sequence similarities | Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Carbohydrate metabolism Galactose metabolism |
| Ligand | Iron Metal-binding Zinc |
| Molecular function | Nucleotidyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cellular response to stress Inferred from expression pattern. Source: GeneDB_SPombe galactose metabolic processInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytosol Inferred from direct assay. Source: GeneDB_SPombe nucleusInferred from direct assay. Source: GeneDB_SPombe |
| Molecular function | UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC iron ion bindingInferred from electronic annotation. Source: UniProtKB-KW zinc ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 369 | 369 | Galactose-1-phosphate uridylyltransferase | PRO_0000169891 | |||||
Sites | |||||||||
| Active site | 185 | 1 | Tele-UMP-histidine intermediate By similarity | ||||||
| Metal binding | 54 | 1 | Zinc By similarity | ||||||
| Metal binding | 57 | 1 | Zinc By similarity | ||||||
| Metal binding | 127 | 1 | Zinc By similarity | ||||||
| Metal binding | 183 | 1 | Zinc By similarity | ||||||
| Metal binding | 201 | 1 | Iron By similarity | ||||||
| Metal binding | 300 | 1 | Iron By similarity | ||||||
| Metal binding | 317 | 1 | Iron By similarity | ||||||
| Metal binding | 319 | 1 | Iron By similarity | ||||||
Sequences
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References
| [1] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. Nurse P.Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CU329671 Genomic DNA. Translation: CAC21412.1. |
| RefSeq | NP_596856.1. |
3D structure databases | |
| SMR | Q9HDU5. Positions 5-367. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q9HDU5. |
Genome annotation databases | |
| GeneID | 2541407. |
| GenomeReviews | Gene locus gal7 in contig CU329671_GR. |
| KEGG | spo:SPBPB2B2.10c. |
| NMPDR | fig|4896.1.peg.2722. |
Organism-specific databases | |
| GeneDB_Spombe | SPBPB2B2.10c. |
Phylogenomic databases | |
| eggNOG | fuNOG06817. |
| HOGENOM | HBG600409. |
| OMA | HRRLNPL. |
| OrthoDB | EOG9Q2FXT. |
| PhylomeDB | Q9HDU5. |
Enzyme and pathway databases | |
| BRENDA | 2.7.7.12. 653. |
Gene expression databases | |
| ArrayExpress | Q9HDU5. |
Family and domain databases | |
| InterPro | IPR001937. GalP_UDPtransf1. IPR019779. GalP_UDPtransf1_His-AS. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. IPR011146. His_triad-like_motif. IPR011151. His_triad_motif. [Graphical view] |
| Gene3D | G3DSA:3.30.428.10. His_triad_motif. 2 hits. |
| PANTHER | PTHR11943. GalP_UDPtransf1. 1 hit. |
| Pfam | PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view] |
| PIRSF | PIRSF000808. GalT. 1 hit. |
| TIGRFAMs | TIGR00209. galT_1. 1 hit. |
| PROSITE | PS00117. GAL_P_UDP_TRANSF_I. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GAL7_SCHPO | ||||||||
| Accession | Primary (citable) accession number: Q9HDU5 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

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