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Q9HCJ6 (VAT1L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Synaptic vesicle membrane protein VAT-1 homolog-like
EC=1.-.-.-
Gene names
Name:VAT1L
Synonyms:KIAA1576
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

Sequence caution

The sequence BAB13402.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 419419Synaptic vesicle membrane protein VAT-1 homolog-like
PRO_0000160922

Secondary structure

1 ........................................................... 419
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9HCJ6 [UniParc].

Last modified September 27, 2004. Version 2.
Checksum: BA962924662987AC

FASTA41945,899
        10         20         30         40         50         60 
MAKEGVEKAE ETEQMIEKEA GKEPAEGGGG DGSHRLGDAQ EMRAVVLAGF GGLNKLRLFR 

        70         80         90        100        110        120 
KAMPEPQDGE LKIRVKACGL NFIDLMVRQG NIDNPPKTPL VPGFECSGIV EALGDSVKGY 

       130        140        150        160        170        180 
EIGDRVMAFV NYNAWAEVVC TPVEFVYKIP DDMSFSEAAA FPMNFVTAYV MLFEVANLRE 

       190        200        210        220        230        240 
GMSVLVHSAG GGVGQAVAQL CSTVPNVTVF GTASTFKHEA IKDSVTHLFD RNADYVQEVK 

       250        260        270        280        290        300 
RISAEGVDIV LDCLCGDNTG KGLSLLKPLG TYILYGSSNM VTGETKSFFS FAKSWWQVEK 

       310        320        330        340        350        360 
VNPIKLYEEN KVIAGFSLLN LLFKQGRAGL IRGVVEKLIG LYNQKKIKPV VDSLWALEEV 

       370        380        390        400        410 
KEAMQRIHDR GNIGKLILDV EKTPTPLMAN DSTETSEAGE EEEDHEGDSE NKERMPFIQ

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References

[1]"Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T., Kikuno R., Nakayama M., Hirosawa M., Ohara O.
DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB046796 mRNA. Translation: BAB13402.1. Different initiation.
BC033537 mRNA. Translation: AAH33537.1.
IPIIPI00030578.
RefSeqNP_065978.1. NM_020927.1.
UniGeneHs.461405.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4A27X-ray2.10A/B41-387[»]
ProteinModelPortalQ9HCJ6.
ModBaseSearch...

Protein-protein interaction databases

STRING9606.ENSP00000303129.

PTM databases

PhosphoSiteQ9HCJ6.

Polymorphism databases

DMDM52783098.

Proteomic databases

PaxDbQ9HCJ6.
PeptideAtlasQ9HCJ6.
PRIDEQ9HCJ6.

Protocols and materials databases

DNASU57687.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000302536; ENSP00000303129; ENSG00000171724.
GeneID57687.
KEGGhsa:57687.
UCSCuc002ffg.1. human.

Organism-specific databases

CTD57687.
GeneCardsGC16P077822.
HGNCHGNC:29315. VAT1L.
HPACAB046032.
HPA044061.
neXtProtNX_Q9HCJ6.
PharmGKBPA164727497.
HUGESearch...
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0604.
HOGENOMHOG000294681.
HOVERGENHBG002466.
InParanoidQ9HCJ6.
OMACLCGENT.
OrthoDBEOG4Q58PK.

Gene expression databases

ArrayExpressQ9HCJ6.
BgeeQ9HCJ6.
CleanExHS_VAT1L.
GenevestigatorQ9HCJ6.
GermOnlineENSG00000171724. Homo sapiens.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR013154. ADH_GroES-like.
IPR002085. ADH_SF_Zn-type.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR002364. Quin_OxRdtase/zeta-crystal_CS.
[Graphical view]
PANTHERPTHR11695. PTHR11695. 1 hit.
PfamPF08240. ADH_N. 1 hit.
[Graphical view]
SUPFAMSSF50129. GroES_like. 1 hit.
PROSITEPS01162. QOR_ZETA_CRYSTAL. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSVAT1L. human.
EvolutionaryTraceQ9HCJ6.
GenomeRNAi57687.
NextBio64514.

Entry information

Entry nameVAT1L_HUMAN
AccessionPrimary (citable) accession number: Q9HCJ6
Secondary accession number(s): Q8IYW8
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: September 27, 2004
Last modified: May 1, 2013
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents