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Q9HCJ5

- ZSWM6_HUMAN

UniProt

Q9HCJ5 - ZSWM6_HUMAN

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Protein
Zinc finger SWIM domain-containing protein 6
Gene
ZSWIM6, KIAA1577
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri246 – 28338SWIM-type
Add
BLAST

GO - Molecular functioni

  1. zinc ion binding Source: InterPro

GO - Biological processi

  1. neuron projection morphogenesis Source: Ensembl
  2. regulation of neuron migration Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger SWIM domain-containing protein 6
Gene namesi
Name:ZSWIM6
Synonyms:KIAA1577
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 5

Organism-specific databases

HGNCiHGNC:29316. ZSWIM6.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134910181.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12151215Zinc finger SWIM domain-containing protein 6
PRO_0000223105Add
BLAST

Proteomic databases

MaxQBiQ9HCJ5.
PaxDbiQ9HCJ5.
PRIDEiQ9HCJ5.

PTM databases

PhosphoSiteiQ9HCJ5.

Expressioni

Gene expression databases

BgeeiQ9HCJ5.
CleanExiHS_ZSWIM6.
GenevestigatoriQ9HCJ5.

Organism-specific databases

HPAiHPA035938.

Interactioni

Protein-protein interaction databases

BioGridi121714. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ9HCJ5.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi19 – 154136Gly-rich
Add
BLAST
Compositional biasi155 – 1584Poly-Ser
Compositional biasi160 – 19738Ala-rich
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiNOG322060.
HOGENOMiHOG000231419.
HOVERGENiHBG058098.
InParanoidiQ9HCJ5.
OMAiEQKSSWL.
OrthoDBiEOG74J970.
PhylomeDBiQ9HCJ5.
TreeFamiTF324881.

Family and domain databases

InterProiIPR007527. Znf_SWIM.
[Graphical view]
PROSITEiPS50966. ZF_SWIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HCJ5-1 [UniParc]FASTAAdd to Basket

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MAERGQQPPP AKRLCCRPGG GGGGGGSSGG GGGAGGGYSS ACRPGPRAGG     50
AAAAAACGGG AALGLLPPGK TQSPESLLDI AARRVAEKWP FQRVEERFER 100
IPEPVQRRIV YWSFPRSERE ICMYSSFNTG GGAAGGPGDD SGGGGGAGGG 150
GGGGSSSSPA ATSAAATSAA AAAAAAAAAA AAAAGAGAPS VGAAGAADGG 200
DETRLPFRRG IALLESGCVD NVLQVGFHLS GTVTEPAIQS EPETVCNVAI 250
SFDRCKITSV TCSCGNKDIF YCAHVVALSL YRIRKPDQVK LHLPISETLF 300
QMNRDQLQKF VQYLITVHHT EVLPTAQKLA DEILSQNSEI NQVHGAPDPT 350
AGASIDDENC WHLDEEQVQE QVKLFLSQGG YHGSGKQLNL LFAKVREMLK 400
MRDSNGARML TLITEQFMAD PRLSLWRQQG TAMTDKYRQL WDELGALWMC 450
IVLNPHCKLE QKASWLKQLK KWNSVDVCPW EDGNHGSELP NLTNALPQGA 500
NANQDSSNRP HRTVFTRAIE ACDLHWQDSH LQHIISSDLY TNYCYHDDTE 550
NSLFDSRGWP LWHEHVPTAC ARVDALRSHG YPREALRLAI AIVNTLRRQQ 600
QKQLEMFRTQ KKELPHKNIT SITNLEGWVG HPLDPVGTLF SSLMEACRID 650
DENLSGFSDF TENMGQCKSL EYQHLPAHKF LEEGESYLTL AVEVALIGLG 700
QQRIMPDGLY TQEKVCRNEE QLISKLQEIE LDDTLVKIFR KQAVFLLEAG 750
PYSGLGEIIH RESVPMHTFA KYLFTSLLPH DAELAYKIAL RAMRLLVLES 800
TAPSGDLTRP HHIASVVPNR YPRWFTLSHI ESQQCELAST MLTAAKGDVR 850
RLETVLESIQ KNIHSSSHIF KLAQDAFKIA TLMDSLPDIT LLKVSLELGL 900
QVMRMTLSTL NWRRREMVRW LVTCATEVGV YALDSIMQTW FTLFTPTEAT 950
SIVATTVMSN STIVRLHLDC HQQEKLASSA RTLALQCAMK DPQNCALSAL 1000
TLCEKDHIAF ETAYQIVLDA ATTGMSYTQL FTIARYMEHR GYPMRAYKLA 1050
TLAMTHLNLS YNQDTHPAIN DVLWACALSH SLGKNELAAI IPLVVKSVKC 1100
ATVLSDILRR CTLTTPGMVG LHGRRNSGKL MSLDKAPLRQ LLDATIGAYI 1150
NTTHSRLTHI SPRHYSEFIE FLSKARETFL MAHDGHIQFT QFIDNLKQIY 1200
KGKKKLMMLV RERFG 1215
Length:1,215
Mass (Da):133,470
Last modified:May 5, 2009 - v2
Checksum:i828B5AA0644EECE0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC122718 Genomic DNA. No translation available.
AC008836 Genomic DNA. No translation available.
AB046797 mRNA. Translation: BAB13403.1.
CCDSiCCDS47215.1.
RefSeqiNP_065979.1. NM_020928.1.
UniGeneiHs.744939.

Genome annotation databases

EnsembliENST00000252744; ENSP00000252744; ENSG00000130449.
GeneIDi57688.
KEGGihsa:57688.
UCSCiuc003jsr.3. human.

Polymorphism databases

DMDMi229462808.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC122718 Genomic DNA. No translation available.
AC008836 Genomic DNA. No translation available.
AB046797 mRNA. Translation: BAB13403.1 .
CCDSi CCDS47215.1.
RefSeqi NP_065979.1. NM_020928.1.
UniGenei Hs.744939.

3D structure databases

ProteinModelPortali Q9HCJ5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 121714. 1 interaction.

PTM databases

PhosphoSitei Q9HCJ5.

Polymorphism databases

DMDMi 229462808.

Proteomic databases

MaxQBi Q9HCJ5.
PaxDbi Q9HCJ5.
PRIDEi Q9HCJ5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000252744 ; ENSP00000252744 ; ENSG00000130449 .
GeneIDi 57688.
KEGGi hsa:57688.
UCSCi uc003jsr.3. human.

Organism-specific databases

CTDi 57688.
GeneCardsi GC05P060628.
H-InvDB HIX0004892.
HGNCi HGNC:29316. ZSWIM6.
HPAi HPA035938.
neXtProti NX_Q9HCJ5.
PharmGKBi PA134910181.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG322060.
HOGENOMi HOG000231419.
HOVERGENi HBG058098.
InParanoidi Q9HCJ5.
OMAi EQKSSWL.
OrthoDBi EOG74J970.
PhylomeDBi Q9HCJ5.
TreeFami TF324881.

Miscellaneous databases

ChiTaRSi ZSWIM6. human.
GenomeRNAii 57688.
NextBioi 64517.
PROi Q9HCJ5.

Gene expression databases

Bgeei Q9HCJ5.
CleanExi HS_ZSWIM6.
Genevestigatori Q9HCJ5.

Family and domain databases

InterProi IPR007527. Znf_SWIM.
[Graphical view ]
PROSITEi PS50966. ZF_SWIM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Kikuno R., Nakayama M., Hirosawa M., Ohara O.
    DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 473-1215.
    Tissue: Brain.

Entry informationi

Entry nameiZSWM6_HUMAN
AccessioniPrimary (citable) accession number: Q9HCJ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: May 5, 2009
Last modified: July 9, 2014
This is version 79 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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