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Q9HCF6 (TRPM3_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 110. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transient receptor potential cation channel subfamily M member 3
Alternative name(s):
Long transient receptor potential channel 3
Short name=LTrpC-3
Short name=LTrpC3
Melastatin-2
Short name=MLSN2
Gene names
Name:TRPM3
Synonyms:KIAA1616, LTRPC3
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1732 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation. Ref.1 Ref.5

Subcellular location

Membrane; Multi-pass membrane protein Ref.5.

Tissue specificity

Expressed primarily in the kidney and, at lower levels, in brain, testis, ovary, pancreas and spinal cord. Expression in the brain and kidney was determined at protein level. In the kidney, expressed predominantly in the collecting tubular epithelium in the medulla, medullary rays, and periglomerular regions; in the brain, highest levels are found in the cerebellum, choroid plexus, the locus coeruleus, the posterior thalamus and the substantia nigra. Down-regulated in renal tumors compared to normal kidney. Ref.1 Ref.5

Sequence similarities

Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM3 sub-subfamily. [View classification]

Sequence caution

The sequence CAB66480.2 differs from that shown. Reason: Cloning artifact in C-terminus.

The sequence CAM13096.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAM13169.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAM15782.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAM17596.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAM22746.1 differs from that shown. Reason: Erroneous gene model prediction.

Alternative products

This entry describes 11 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9HCF6-1)

Also known as: TRPM3f;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9HCF6-2)

Also known as: TRPM3a;

The sequence of this isoform differs from the canonical sequence as follows:
     326-350: Missing.
Isoform 3 (identifier: Q9HCF6-3)

Also known as: TRPM3b;

The sequence of this isoform differs from the canonical sequence as follows:
     326-350: Missing.
     569-569: K → KREYPGFGWIYFK
Isoform 4 (identifier: Q9HCF6-4)

Also known as: TRPM3d;

The sequence of this isoform differs from the canonical sequence as follows:
     326-350: Missing.
     617-626: Missing.
Isoform 5 (identifier: Q9HCF6-5)

Also known as: TRPM3e;

The sequence of this isoform differs from the canonical sequence as follows:
     326-350: Missing.
     569-569: K → KREYPGFGWIYFK
     617-626: Missing.
Isoform 6 (identifier: Q9HCF6-6)

Also known as: TRPM3c;

The sequence of this isoform differs from the canonical sequence as follows:
     326-350: Missing.
     1088-1088: P → RKQVYDSHTPKSA
Isoform 7 (identifier: Q9HCF6-7)

The sequence of this isoform differs from the canonical sequence as follows:
     617-626: Missing.
Isoform 8 (identifier: Q9HCF6-8)

The sequence of this isoform differs from the canonical sequence as follows:
     326-350: Missing.
     535-552: Missing.
     617-626: Missing.
Isoform 10 (identifier: Q9HCF6-10)

The sequence of this isoform differs from the canonical sequence as follows:
     326-350: Missing.
     1344-1350: GEETMSP → EHPLYSV
     1351-1732: Missing.
Isoform 11 (identifier: Q9HCF6-11)

The sequence of this isoform differs from the canonical sequence as follows:
     1-59: MPEPWGTVYF...AFLPSVRLLK → MGKKWRDAAE...RSGLPSQQTP
Isoform 12 (identifier: Q9HCF6-12)

The sequence of this isoform differs from the canonical sequence as follows:
     1-153: Missing.
     326-350: Missing.
     409-1732: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 17321732Transient receptor potential cation channel subfamily M member 3
PRO_0000215328

Regions

Transmembrane4 – 2421Helical; Potential
Topological domain25 – 794770Cytoplasmic Potential
Transmembrane795 – 81521Helical; Potential
Topological domain816 – 89782Extracellular Potential
Transmembrane898 – 91821Helical; Potential
Topological domain919 – 96446Cytoplasmic Potential
Transmembrane965 – 98521Helical; Potential
Topological domain986 – 99510Extracellular Potential
Transmembrane996 – 101621Helical; Potential
Topological domain1017 – 102812Cytoplasmic Potential
Transmembrane1029 – 104921Helical; Potential
Topological domain1050 – 111667Extracellular Potential
Transmembrane1117 – 113721Helical; Potential
Topological domain1138 – 1732595Cytoplasmic Potential
Coiled coil1241 – 130161 Potential

Natural variations

Alternative sequence1 – 153153Missing in isoform 12.
VSP_043515
Alternative sequence1 – 5959MPEPW…VRLLK → MGKKWRDAAEMERGCSDRED NAESRRRSRSASRGRFAESW KRLSSKQGSTKRSGLPSQQT P in isoform 11.
VSP_039107
Alternative sequence326 – 35025Missing in isoform 2, isoform 3, isoform 4, isoform 5, isoform 6, isoform 8, isoform 10 and isoform 12.
VSP_012826
Alternative sequence409 – 17321324Missing in isoform 12.
VSP_043516
Alternative sequence535 – 55218Missing in isoform 8.
VSP_012827
Alternative sequence5691K → KREYPGFGWIYFK in isoform 3 and isoform 5.
VSP_012828
Alternative sequence617 – 62610Missing in isoform 4, isoform 5, isoform 7 and isoform 8.
VSP_012829
Alternative sequence10881P → RKQVYDSHTPKSA in isoform 6.
VSP_012830
Alternative sequence1344 – 13507GEETMSP → EHPLYSV in isoform 10.
VSP_012831
Alternative sequence1351 – 1732382Missing in isoform 10.
VSP_012832
Natural variant16531T → I.
Corresponds to variant rs13440436 [ dbSNP | Ensembl ].
VAR_057305
Natural variant16951R → Q.
Corresponds to variant rs6560142 [ dbSNP | Ensembl ].
VAR_021257
Natural variant17171R → K. Ref.7
Corresponds to variant rs41287373 [ dbSNP | Ensembl ].
VAR_061862
Natural variant17321N → T. Ref.5 Ref.6 Ref.7
Corresponds to variant rs17535963 [ dbSNP | Ensembl ].
VAR_057306

Experimental info

Sequence conflict3351R → H in BAC55103. Ref.6
Sequence conflict6951C → Y in BAC55106. Ref.6
Sequence conflict10321D → E in BAC55106. Ref.6
Sequence conflict17301K → Q in BAC55104. Ref.6

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 (TRPM3f) [UniParc].

Last modified February 8, 2011. Version 4.
Checksum: 0D6BE312C56646A4

FASTA1,732197,571
        10         20         30         40         50         60 
MPEPWGTVYF LGIAQVFSFL FSWWNLEGVM NQADAPRPLN WTIRKLCHAA FLPSVRLLKA 

        70         80         90        100        110        120 
QKSWIERAFY KRECVHIIPS TKDPHRCCCG RLIGQHVGLT PSISVLQNEK NESRLSRNDI 

       130        140        150        160        170        180 
QSEKWSISKH TQLSPTDAFG TIEFQGGGHS NKAMYVRVSF DTKPDLLLHL MTKEWQLELP 

       190        200        210        220        230        240 
KLLISVHGGL QNFELQPKLK QVFGKGLIKA AMTTGAWIFT GGVNTGVIRH VGDALKDHAS 

       250        260        270        280        290        300 
KSRGKICTIG IAPWGIVENQ EDLIGRDVVR PYQTMSNPMS KLTVLNSMHS HFILADNGTT 

       310        320        330        340        350        360 
GKYGAEVKLR RQLEKHISLQ KINTRCLPFF SLDSRLFYSF WGSCQLDSVG IGQGVPVVAL 

       370        380        390        400        410        420 
IVEGGPNVIS IVLEYLRDTP PVPVVVCDGS GRASDILAFG HKYSEEGGLI NESLRDQLLV 

       430        440        450        460        470        480 
TIQKTFTYTR TQAQHLFIIL MECMKKKELI TVFRMGSEGH QDIDLAILTA LLKGANASAP 

       490        500        510        520        530        540 
DQLSLALAWN RVDIARSQIF IYGQQWPVGS LEQAMLDALV LDRVDFVKLL IENGVSMHRF 

       550        560        570        580        590        600 
LTISRLEELY NTRHGPSNTL YHLVRDVKKG NLPPDYRISL IDIGLVIEYL MGGAYRCNYT 

       610        620        630        640        650        660 
RKRFRTLYHN LFGPKRPKAL KLLGMEDDIP LRRGRKTTKK REEEVDIDLD DPEINHFPFP 

       670        680        690        700        710        720 
FHELMVWAVL MKRQKMALFF WQHGEEAMAK ALVACKLCKA MAHEASENDM VDDISQELNH 

       730        740        750        760        770        780 
NSRDFGQLAV ELLDQSYKQD EQLAMKLLTY ELKNWSNATC LQLAVAAKHR DFIAHTCSQM 

       790        800        810        820        830        840 
LLTDMWMGRL RMRKNSGLKV ILGILLPPSI LSLEFKNKDD MPYMSQAQEI HLQEKEAEEP 

       850        860        870        880        890        900 
EKPTKEKEEE DMELTAMLGR NNGESSRKKD EEEVQSKHRL IPLGRKIYEF YNAPIVKFWF 

       910        920        930        940        950        960 
YTLAYIGYLM LFNYIVLVKM ERWPSTQEWI VISYIFTLGI EKMREILMSE PGKLLQKVKV 

       970        980        990       1000       1010       1020 
WLQEYWNVTD LIAILLFSVG MILRLQDQPF RSDGRVIYCV NIIYWYIRLL DIFGVNKYLG 

      1030       1040       1050       1060       1070       1080 
PYVMMIGKMM IDMMYFVIIM LVVLMSFGVA RQAILFPNEE PSWKLAKNIF YMPYWMIYGE 

      1090       1100       1110       1120       1130       1140 
VFADQIDPPC GQNETREDGK IIQLPPCKTG AWIVPAIMAC YLLVANILLV NLLIAVFNNT 

      1150       1160       1170       1180       1190       1200 
FFEVKSISNQ VWKFQRYQLI MTFHERPVLP PPLIIFSHMT MIFQHLCCRW RKHESDPDER 

      1210       1220       1230       1240       1250       1260 
DYGLKLFITD DELKKVHDFE EQCIEEYFRE KDDRFNSSND ERIRVTSERV ENMSMRLEEV 

      1270       1280       1290       1300       1310       1320 
NEREHSMKAS LQTVDIRLAQ LEDLIGRMAT ALERLTGLER AESNKIRSRT SSDCTDAAYI 

      1330       1340       1350       1360       1370       1380 
VRQSSFNSQE GNTFKLQESI DPAGEETMSP TSPTLMPRMR SHSFYSVNMK DKGGIEKLES 

      1390       1400       1410       1420       1430       1440 
IFKERSLSLH RATSSHSVAK EPKAPAAPAN TLAIVPDSRR PSSCIDIYVS AMDELHCDID 

      1450       1460       1470       1480       1490       1500 
PLDNSVNILG LGEPSFSTPV PSTAPSSSAY ATLAPTDRPP SRSIDFEDIT SMDTRSFSSD 

      1510       1520       1530       1540       1550       1560 
YTHLPECQNP WDSEPPMYHT IERSKSSRYL ATTPFLLEEA PIVKSHSFMF SPSRSYYANF 

      1570       1580       1590       1600       1610       1620 
GVPVKTAEYT SITDCIDTRC VNAPQAIADR AAFPGGLGDK VEDLTCCHPE REAELSHPSS 

      1630       1640       1650       1660       1670       1680 
DSEENEAKGR RATIAISSQE GDNSERTLSN NITVPKIERA NSYSAEEPSA PYAHTRKSFS 

      1690       1700       1710       1720       1730 
ISDKLDRQRN TASLRNPFQR SKSSKPEGRG DSLSMRRLSR TSAFQSFESK HN 

« Hide

Isoform 2 (TRPM3a) [UniParc].

Checksum: 16522E65FD2FAA3F
Show »

FASTA1,707194,714
Isoform 3 (TRPM3b) [UniParc].

Checksum: 27EAFF76AFB0A46B
Show »

FASTA1,719196,259
Isoform 4 (TRPM3d) [UniParc].

Checksum: 144786F6D67B4F0B
Show »

FASTA1,697193,632
Isoform 5 (TRPM3e) [UniParc].

Checksum: DA6133571BA70002
Show »

FASTA1,709195,177
Isoform 6 (TRPM3c) [UniParc].

Checksum: 46BEADD398188191
Show »

FASTA1,719196,115
Isoform 7 [UniParc].

Checksum: E30BDDE5FB3E061B
Show »

FASTA1,722196,490
Isoform 8 [UniParc].

Checksum: C90DF3FAF79D9637
Show »

FASTA1,679191,441
Isoform 10 [UniParc].

Checksum: 837BEDE795F5E400
Show »

FASTA1,325152,656
Isoform 11 [UniParc].

Checksum: D536EBCD7F526C10
Show »

FASTA1,734197,679
Isoform 12 [UniParc].

Checksum: 237AF35F9D6036F2
Show »

FASTA23025,159

References

« Hide 'large scale' references
[1]"Molecular and functional characterization of the melastatin-related cation channel TRPM3."
Grimm C., Kraft R., Sauerbruch S., Schultz G., Harteneck C.
J. Biol. Chem. 278:21493-21501(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 10), FUNCTION, TISSUE SPECIFICITY.
Tissue: Fetal brain.
[2]"DNA sequence and analysis of human chromosome 9."
Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. expand/collapse author list , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 12).
[4]"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., Ottenwaelder B., Obermaier B. expand/collapse author list , Tampe J., Heubner D., Wambutt R., Korn B., Klein M., Poustka A.
Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-324 (ISOFORM 11).
Tissue: Amygdala.
[5]"Expression and characterization of human transient receptor potential melastatin 3 (hTRPM3)."
Lee N., Chen J., Sun L., Wu S., Gray K.R., Rich A., Huang M., Lin J.-H., Feder J.N., Janovitz E.B., Levesque P.C., Blanar M.A.
J. Biol. Chem. 278:20890-20897(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 154-1732 (ISOFORMS 1; 2; 3; 4; 5 AND 6), VARIANT THR-1732, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[6]"ProX human full-length cDNA cloning project."
Okabayashi K., Hirano K., Sano M., Murahashi Y., Miyauchi A., Gonoi T.
Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 154-1732 (ISOFORMS 1; 2; 4; 7 AND 8), VARIANT THR-1732.
Tissue: Brain.
[7]"Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T., Kikuno R., Nakayama M., Hirosawa M., Ohara O.
DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 716-1732 (ISOFORMS 1/2/3/4/5/7/8), VARIANTS LYS-1717 AND THR-1732.
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ505025 mRNA. Translation: CAD43604.1.
AJ505026 mRNA. Translation: CAD43605.1.
AL159990, AL356318 Genomic DNA. Translation: CAI12193.1.
AL356318, AL159990 Genomic DNA. Translation: CAI96096.1.
AL159990 expand/collapse EMBL AC list , AL161913, AL356318, AL358786, AL442645 Genomic DNA. Translation: CAM13096.1. Sequence problems.
AL356318 expand/collapse EMBL AC list , AL159990, AL161913, AL358786, AL442645 Genomic DNA. Translation: CAM13169.1. Sequence problems.
AL358786 expand/collapse EMBL AC list , AL159990, AL161913, AL356318, AL442645 Genomic DNA. Translation: CAM15782.1. Sequence problems.
AL442645 expand/collapse EMBL AC list , AL159990, AL161913, AL356318, AL358786 Genomic DNA. Translation: CAM17596.1. Sequence problems.
AL161913 expand/collapse EMBL AC list , AL159990, AL356318, AL358786, AL442645 Genomic DNA. Translation: CAM22746.1. Sequence problems.
AL160273 Genomic DNA. No translation available.
AL391819 Genomic DNA. No translation available.
AL592438 Genomic DNA. No translation available.
BC121821 mRNA. Translation: AAI21822.2.
BC134414 mRNA. Translation: AAI34415.1.
BC142972 mRNA. Translation: AAI42973.1.
AL136545 mRNA. Translation: CAB66480.2. Sequence problems.
AF536748 mRNA. Translation: AAO49153.1.
AF536749 mRNA. Translation: AAO49154.1.
AF536750 mRNA. Translation: AAO49155.1.
AF536751 mRNA. Translation: AAO49156.1.
AF536752 mRNA. Translation: AAO49157.1.
AF536753 mRNA. Translation: AAO49158.1.
AB099661 mRNA. Translation: BAC55102.1.
AB099662 mRNA. Translation: BAC55103.1.
AB099663 mRNA. Translation: BAC55104.1.
AB099664 mRNA. Translation: BAC55105.1.
AB099665 mRNA. Translation: BAC55106.1.
AB046836 mRNA. Translation: BAB13442.1.
RefSeqNP_001007472.2. NM_001007471.2.
NP_996831.1. NM_206948.2.
XP_005252275.1. XM_005252218.2.
UniGeneHs.47288.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-4713703.

Chemistry

GuidetoPHARMACOLOGY495.

Protein family/group databases

TCDB1.A.4.5.6. the transient receptor potential ca(2+) channel (trp-cc) family.

PTM databases

PhosphoSiteQ9HCF6.

Polymorphism databases

DMDM322510140.

Proteomic databases

PaxDbQ9HCF6.
PRIDEQ9HCF6.

Protocols and materials databases

DNASU80036.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000361823; ENSP00000355395; ENSG00000083067. [Q9HCF6-12]
ENST00000377110; ENSP00000366314; ENSG00000083067. [Q9HCF6-2]
ENST00000377111; ENSP00000366315; ENSG00000083067. [Q9HCF6-10]
ENST00000423814; ENSP00000389542; ENSG00000083067. [Q9HCF6-11]
GeneID80036.
KEGGhsa:80036.
UCSCuc004ahv.3. human. [Q9HCF6-8]
uc004ahw.3. human. [Q9HCF6-1]
uc004ahz.3. human. [Q9HCF6-5]
uc004aia.3. human. [Q9HCF6-2]
uc004aib.3. human. [Q9HCF6-4]
uc004aic.3. human. [Q9HCF6-10]
uc004aig.3. human. [Q9HCF6-12]

Organism-specific databases

CTD80036.
GeneCardsGC09M073149.
HGNCHGNC:17992. TRPM3.
MIM608961. gene.
neXtProtNX_Q9HCF6.
PharmGKBPA38271.
HUGESearch...
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG253824.
HOGENOMHOG000230920.
HOVERGENHBG058254.
InParanoidQ9HCF6.
KOK04978.
OMAKFWFYTL.
OrthoDBEOG7NPFSC.
PhylomeDBQ9HCF6.
TreeFamTF314204.

Enzyme and pathway databases

ReactomeREACT_15518. Transmembrane transport of small molecules.

Gene expression databases

ArrayExpressQ9HCF6.
BgeeQ9HCF6.
GenevestigatorQ9HCF6.

Family and domain databases

InterProIPR005821. Ion_trans_dom.
[Graphical view]
PfamPF00520. Ion_trans. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSTRPM3. human.
GeneWikiTRPM3.
GenomeRNAi80036.
NextBio70216.
PROQ9HCF6.
SOURCESearch...

Entry information

Entry nameTRPM3_HUMAN
AccessionPrimary (citable) accession number: Q9HCF6
Secondary accession number(s): A2A3F6 expand/collapse secondary AC list , A9Z1Y7, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01, Q9H0X2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: February 8, 2011
Last modified: April 16, 2014
This is version 110 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 9

Human chromosome 9: entries, gene names and cross-references to MIM