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Protein
Submitted name:

Cathepsin L, isoform CRA_b

Gene

CTSL

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BRENDAi3.4.22.15. 2681.

Names & Taxonomyi

Protein namesi
Submitted name:
Cathepsin L, isoform CRA_bImported
Gene namesi
Name:CTSLImported
ORF Names:hCG_30369Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiQ9HBQ7.
PRIDEiQ9HBQ7.

Expressioni

Gene expression databases

BgeeiENSG00000135047.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000345344.

Structurei

3D structure databases

ProteinModelPortaliQ9HBQ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 150Pept_C1InterPro annotationAdd BLAST150

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1543. Eukaryota.
COG4870. LUCA.
HOVERGENiHBG011513.

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HBQ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYAFQYVQD NGGLDSEESY PYEATEESCK YNPKYSVAND TGFVDIPKQE
60 70 80 90 100
KALMKAVATV GPISVAIDAG HESFLFYKEG IYFEPDCSSE DMDHGVLVVG
110 120 130 140 150
YGFESTESDN NKYWLVKNSW GEEWGMGGYV KMAKDRRNHC GIASAASYPT

V
Length:151
Mass (Da):16,839
Last modified:March 1, 2001 - v1
Checksum:i539C686EE95C80B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF217997 mRNA. Translation: AAG17239.1.
CH471089 Genomic DNA. Translation: EAW62735.1.
RefSeqiNP_001244902.1. NM_001257973.1.
UniGeneiHs.731507.

Genome annotation databases

GeneIDi1514.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF217997 mRNA. Translation: AAG17239.1.
CH471089 Genomic DNA. Translation: EAW62735.1.
RefSeqiNP_001244902.1. NM_001257973.1.
UniGeneiHs.731507.

3D structure databases

ProteinModelPortaliQ9HBQ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000345344.

Proteomic databases

PeptideAtlasiQ9HBQ7.
PRIDEiQ9HBQ7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1514.

Organism-specific databases

CTDi1514.

Phylogenomic databases

eggNOGiKOG1543. Eukaryota.
COG4870. LUCA.
HOVERGENiHBG011513.

Enzyme and pathway databases

BRENDAi3.4.22.15. 2681.

Miscellaneous databases

GenomeRNAii1514.

Gene expression databases

BgeeiENSG00000135047.

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9HBQ7_HUMAN
AccessioniPrimary (citable) accession number: Q9HBQ7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.