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Protein
Submitted name:

Interferon regulatory factor-7H

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to DNA damage stimulus Source: UniProtKB
  • induction of host immune response by virus Source: UniProtKB
  • inflammatory response Source: UniProtKB
  • passive induction of host immune response by virus Source: UniProtKB
  • response to virus Source: UniProtKB
  • transcription initiation from RNA polymerase II promoter Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor-7HImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: UniProtKB
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9HB64.
PRIDEiQ9HB64.

Expressioni

Gene expression databases

BgeeiQ9HB64.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000329411.

Structurei

3D structure databases

ProteinModelPortaliQ9HB64.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 128105IRF tryptophan pentad repeat DNA-bindingInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IWNR. Eukaryota.
ENOG4111G85. LUCA.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00605. IRF. 1 hit.
[Graphical view]
PRINTSiPR00267. INTFRNREGFCT.
SMARTiSM00348. IRF. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9HB64-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVPERPAAG PDSPRPGTRR AAPRVLFGEW LLGEISSGCY EGLQWLDEAR
60 70 80 90 100
TCFRVPWKHF ARKDLSEADA RIFKAWAVAR GRWPPSSRGG GPPPEAETAE
110 120
RAGWKTNFRC ALRSTRRFVM LRDNSGDP
Length:128
Mass (Da):14,363
Last modified:March 1, 2001 - v1
Checksum:i09B5B6F3CC11BB15
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei128 – 1281Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF277159 Genomic DNA. Translation: AAG30003.1.
UniGeneiHs.166120.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF277159 Genomic DNA. Translation: AAG30003.1.
UniGeneiHs.166120.

3D structure databases

ProteinModelPortaliQ9HB64.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000329411.

Proteomic databases

PaxDbiQ9HB64.
PRIDEiQ9HB64.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IWNR. Eukaryota.
ENOG4111G85. LUCA.

Gene expression databases

BgeeiQ9HB64.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00605. IRF. 1 hit.
[Graphical view]
PRINTSiPR00267. INTFRNREGFCT.
SMARTiSM00348. IRF. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Regulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon snd silencing by hypermethylation."
    Lu R., Au W.C., Yeow W.S., Hageman N., Pitha P.M.
    J. Biol. Chem. 275:31805-31812(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9HB64_HUMAN
AccessioniPrimary (citable) accession number: Q9HB64
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: December 9, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.