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Protein

Protein Njmu-R1

Gene

C17orf75

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May have a role in spermatogenesis.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein Njmu-R1
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:30173. C17orf75.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672223.

Polymorphism and mutation databases

BioMutaiC17orf75.
DMDMi114152850.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 396396Protein Njmu-R1PRO_0000096865Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei18 – 181PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9HAS0.
MaxQBiQ9HAS0.
PaxDbiQ9HAS0.
PRIDEiQ9HAS0.

PTM databases

iPTMnetiQ9HAS0.
PhosphoSiteiQ9HAS0.

Expressioni

Tissue specificityi

Highly expressed in testis and also expressed in fetal testis.

Gene expression databases

BgeeiQ9HAS0.
CleanExiHS_C17orf75.
ExpressionAtlasiQ9HAS0. baseline and differential.
GenevisibleiQ9HAS0. HS.

Organism-specific databases

HPAiHPA004061.

Interactioni

Protein-protein interaction databases

BioGridi122087. 12 interactions.
STRINGi9606.ENSP00000225805.

Structurei

3D structure databases

ProteinModelPortaliQ9HAS0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IH4D. Eukaryota.
ENOG410Z836. LUCA.
GeneTreeiENSGT00390000005481.
HOGENOMiHOG000113790.
HOVERGENiHBG006503.
InParanoidiQ9HAS0.
PhylomeDBiQ9HAS0.
TreeFamiTF330763.

Family and domain databases

InterProiIPR028280. Njmu-R1.
[Graphical view]
PfamiPF15053. Njmu-R1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9HAS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPSLQESMD GDEKELESSE EGGSAEERRL EPPSSSHYCL YSYRGSRLAQ
60 70 80 90 100
QRGDSEDGSP SGTNAETPSG DDFSLSLADT NLPSEVEPEL RSFIAKRLSR
110 120 130 140 150
GAVFEGLGNV ASVELKIPGY RVGCYYCLFQ NEKLLPETVT IDSERNPSEY
160 170 180 190 200
VVCFLGGSEK GLELFRLELD KYIQGLKNNM NCEARGLESH IKSYLSSWFE
210 220 230 240 250
DVVCPIQRVV LLFQEKLTFL LHAALSYTPV EVKESDEKTK RDINRFLSVA
260 270 280 290 300
SLQGLIHEGT MTSLCMAMTE EQHKSVVIDC SSSQPQFCNA GSNRFCEDWM
310 320 330 340 350
QAFLNGAKGG NPFLFRQVLE NFKLKAIQDT NNLKRFIRQA EMNHYALFKC
360 370 380 390
YMFLKNCGSG DILLKIVKVE HEEMPEAKNV IAVLEEFMKE ALDQSF
Length:396
Mass (Da):44,622
Last modified:September 5, 2006 - v2
Checksum:i7789DF3685170DB0
GO

Sequence cautioni

The sequence AAG23214.1 differs from that shown. Reason: Frameshift at position 362. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti314 – 3141L → F in AAG23214 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF305686 mRNA. Translation: AAG23214.1. Frameshift.
BC026017 mRNA. Translation: AAH26017.1.
BC035715 mRNA. Translation: AAH35715.1.
BC047325 mRNA. Translation: AAH47325.1.
BC054035 mRNA. Translation: AAH54035.1.
CCDSiCCDS58537.1.
RefSeqiNP_071739.2. NM_022344.3.
UniGeneiHs.655257.

Genome annotation databases

EnsembliENST00000577809; ENSP00000464275; ENSG00000108666.
GeneIDi64149.
KEGGihsa:64149.
UCSCiuc002hhg.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF305686 mRNA. Translation: AAG23214.1. Frameshift.
BC026017 mRNA. Translation: AAH26017.1.
BC035715 mRNA. Translation: AAH35715.1.
BC047325 mRNA. Translation: AAH47325.1.
BC054035 mRNA. Translation: AAH54035.1.
CCDSiCCDS58537.1.
RefSeqiNP_071739.2. NM_022344.3.
UniGeneiHs.655257.

3D structure databases

ProteinModelPortaliQ9HAS0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122087. 12 interactions.
STRINGi9606.ENSP00000225805.

PTM databases

iPTMnetiQ9HAS0.
PhosphoSiteiQ9HAS0.

Polymorphism and mutation databases

BioMutaiC17orf75.
DMDMi114152850.

Proteomic databases

EPDiQ9HAS0.
MaxQBiQ9HAS0.
PaxDbiQ9HAS0.
PRIDEiQ9HAS0.

Protocols and materials databases

DNASUi64149.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000577809; ENSP00000464275; ENSG00000108666.
GeneIDi64149.
KEGGihsa:64149.
UCSCiuc002hhg.4. human.

Organism-specific databases

CTDi64149.
GeneCardsiC17orf75.
HGNCiHGNC:30173. C17orf75.
HPAiHPA004061.
neXtProtiNX_Q9HAS0.
PharmGKBiPA142672223.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IH4D. Eukaryota.
ENOG410Z836. LUCA.
GeneTreeiENSGT00390000005481.
HOGENOMiHOG000113790.
HOVERGENiHBG006503.
InParanoidiQ9HAS0.
PhylomeDBiQ9HAS0.
TreeFamiTF330763.

Miscellaneous databases

GenomeRNAii64149.
NextBioi66058.
PROiQ9HAS0.

Gene expression databases

BgeeiQ9HAS0.
CleanExiHS_C17orf75.
ExpressionAtlasiQ9HAS0. baseline and differential.
GenevisibleiQ9HAS0. HS.

Family and domain databases

InterProiIPR028280. Njmu-R1.
[Graphical view]
PfamiPF15053. Njmu-R1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Njmu-R1: a novel new gene related to spermatogenesis."
    Li J.M., Sha J.H., Zhou Z.M.
    Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Testis.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Eye and Ovary.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  4. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiNJMU_HUMAN
AccessioniPrimary (citable) accession number: Q9HAS0
Secondary accession number(s): Q7Z2H4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: September 5, 2006
Last modified: March 16, 2016
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.