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Q9HAC8

- UBTD1_HUMAN

UniProt

Q9HAC8 - UBTD1_HUMAN

Protein

Ubiquitin domain-containing protein 1

Gene

UBTD1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 101 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ubiquitin domain-containing protein 1
    Gene namesi
    Name:UBTD1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 10

    Organism-specific databases

    HGNCiHGNC:25683. UBTD1.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134976337.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 227227Ubiquitin domain-containing protein 1PRO_0000242674Add
    BLAST

    Proteomic databases

    MaxQBiQ9HAC8.
    PaxDbiQ9HAC8.
    PeptideAtlasiQ9HAC8.
    PRIDEiQ9HAC8.

    PTM databases

    PhosphoSiteiQ9HAC8.

    Expressioni

    Gene expression databases

    BgeeiQ9HAC8.
    CleanExiHS_UBTD1.
    GenevestigatoriQ9HAC8.

    Organism-specific databases

    HPAiHPA034825.

    Interactioni

    Protein-protein interaction databases

    BioGridi123073. 17 interactions.
    IntActiQ9HAC8. 4 interactions.
    MINTiMINT-1439968.
    STRINGi9606.ENSP00000359698.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9HAC8.
    SMRiQ9HAC8. Positions 24-137, 148-222.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini149 – 22476Ubiquitin-likePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 ubiquitin-like domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG278278.
    HOGENOMiHOG000231205.
    HOVERGENiHBG080179.
    InParanoidiQ9HAC8.
    OMAiANDYIIN.
    OrthoDBiEOG76HQ27.
    PhylomeDBiQ9HAC8.
    TreeFamiTF323925.

    Family and domain databases

    InterProiIPR019956. Ubiquitin.
    IPR000626. Ubiquitin-like.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view]
    PfamiPF00240. ubiquitin. 1 hit.
    [Graphical view]
    PRINTSiPR00348. UBIQUITIN.
    SMARTiSM00213. UBQ. 1 hit.
    [Graphical view]
    SUPFAMiSSF54236. SSF54236. 1 hit.
    PROSITEiPS50053. UBIQUITIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9HAC8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGNCVGRQRR ERPAAPGHPR KRAGRNEPLK KERLKWKSDY PMTDGQLRSK    50
    RDEFWDTAPA FEGRKEIWDA LKAAAYAAEA NDHELAQAIL DGASITLPHG 100
    TLCECYDELG NRYQLPIYCL SPPVNLLLEH TEEESLEPPE PPPSVRREFP 150
    LKVRLSTGKD VRLSASLPDT VGQLKRQLHA QEGIEPSWQR WFFSGKLLTD 200
    RTRLQETKIQ KDFVIQVIIN QPPPPQD 227
    Length:227
    Mass (Da):25,938
    Last modified:March 1, 2001 - v1
    Checksum:i7D34DB6027797255
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti133 – 1331E → G in BAD96317. 1 PublicationCurated
    Sequence conflicti173 – 1731Q → L in BAD96317. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK021869 mRNA. Translation: BAB13921.1.
    AK222597 mRNA. Translation: BAD96317.1.
    AL359388 Genomic DNA. Translation: CAI14191.1.
    CH471066 Genomic DNA. Translation: EAW49918.1.
    CH471066 Genomic DNA. Translation: EAW49919.1.
    BC007331 mRNA. Translation: AAH07331.1.
    CCDSiCCDS7465.1.
    RefSeqiNP_079230.1. NM_024954.4.
    UniGeneiHs.500724.

    Genome annotation databases

    EnsembliENST00000370664; ENSP00000359698; ENSG00000165886.
    GeneIDi80019.
    KEGGihsa:80019.
    UCSCiuc001knv.1. human.

    Polymorphism databases

    DMDMi74752759.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK021869 mRNA. Translation: BAB13921.1 .
    AK222597 mRNA. Translation: BAD96317.1 .
    AL359388 Genomic DNA. Translation: CAI14191.1 .
    CH471066 Genomic DNA. Translation: EAW49918.1 .
    CH471066 Genomic DNA. Translation: EAW49919.1 .
    BC007331 mRNA. Translation: AAH07331.1 .
    CCDSi CCDS7465.1.
    RefSeqi NP_079230.1. NM_024954.4.
    UniGenei Hs.500724.

    3D structure databases

    ProteinModelPortali Q9HAC8.
    SMRi Q9HAC8. Positions 24-137, 148-222.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 123073. 17 interactions.
    IntActi Q9HAC8. 4 interactions.
    MINTi MINT-1439968.
    STRINGi 9606.ENSP00000359698.

    PTM databases

    PhosphoSitei Q9HAC8.

    Polymorphism databases

    DMDMi 74752759.

    Proteomic databases

    MaxQBi Q9HAC8.
    PaxDbi Q9HAC8.
    PeptideAtlasi Q9HAC8.
    PRIDEi Q9HAC8.

    Protocols and materials databases

    DNASUi 80019.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000370664 ; ENSP00000359698 ; ENSG00000165886 .
    GeneIDi 80019.
    KEGGi hsa:80019.
    UCSCi uc001knv.1. human.

    Organism-specific databases

    CTDi 80019.
    GeneCardsi GC10P099248.
    HGNCi HGNC:25683. UBTD1.
    HPAi HPA034825.
    neXtProti NX_Q9HAC8.
    PharmGKBi PA134976337.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG278278.
    HOGENOMi HOG000231205.
    HOVERGENi HBG080179.
    InParanoidi Q9HAC8.
    OMAi ANDYIIN.
    OrthoDBi EOG76HQ27.
    PhylomeDBi Q9HAC8.
    TreeFami TF323925.

    Miscellaneous databases

    ChiTaRSi UBTD1. human.
    GenomeRNAii 80019.
    NextBioi 70138.
    PROi Q9HAC8.

    Gene expression databases

    Bgeei Q9HAC8.
    CleanExi HS_UBTD1.
    Genevestigatori Q9HAC8.

    Family and domain databases

    InterProi IPR019956. Ubiquitin.
    IPR000626. Ubiquitin-like.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view ]
    Pfami PF00240. ubiquitin. 1 hit.
    [Graphical view ]
    PRINTSi PR00348. UBIQUITIN.
    SMARTi SM00213. UBQ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54236. SSF54236. 1 hit.
    PROSITEi PS50053. UBIQUITIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Embryo.
    2. Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Coronary artery.
    3. "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
      , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
      Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Placenta.

    Entry informationi

    Entry nameiUBTD1_HUMAN
    AccessioniPrimary (citable) accession number: Q9HAC8
    Secondary accession number(s): D3DR57, Q53HI3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 101 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 10
      Human chromosome 10: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3