Q9HA22 (Q9HA22_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ12385 fis, clone MAMMA1002619, weakly similar to PROBABLE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE K02C4.3 (EC 3.1.2.15) EMBL BAB14037.1
Organism	Homo sapiens (Human) EMBL BAB14037.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	523 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Hydrolase EMBL BAB14037.1
Gene Ontology (GO)
Biological_process	ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	ubiquitin thiolesterase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9HA22 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: C0EA6E695BB441B1	FASTA	523	61,657
	10 20 30 40 50 60 MHPAPRHITE EELSVLESCL HRWRTEIEND TRDLQESISR IHRTIELMYS DKSMIQVPYR 70 80 90 100 110 120 LHAVLVHEGQ ANAGHYWAYI FDHRESRWMK YNDIAVTKSS WEELVRDSFG GYRNASAYCL 130 140 150 160 170 180 MYINDKAQFL IQEEFNKETG QPLVGIETLP PDLRDFVEED NQRFEKELEE WDAQLAQKAL 190 200 210 220 230 240 QEKLLASQKL RESETSVTTA QAAGDPEYLE QPSRSDFSKH LKEETIQIIT KASHEHEDKS 250 260 270 280 290 300 PETVLQSAIK LEYARLVKLA QEDTPPETDY RLHHVVVYFI QNQAPKKIIE KTLLEQFGDR 310 320 330 340 350 360 NLSFDERCHN IMKVAQAKLE MIKPEEVNLE EYEEWHQDYR KFRETTMYLI IGLENFQRES 370 380 390 400 410 420 YIDSLLFLIC AYQNNKELLS KGLYRGHDEE LISHYRRECL LKLNEQAAEL FESGEDREVN 430 440 450 460 470 480 NGLIIMNEFI VPFLPLLLVD EMEEKDILAV EDMRNRWCSY LGQEMEPHLQ EKLTDFLPKL 490 500 510 520 LDCSMEIKSF HEPPKLPSYS THELCERFAR IMLSLSRTPA DGR

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Mammary gland EMBL BAB14037.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK022447 mRNA. Translation: BAB14037.1.
IPI	IPI00219886.
UniGene	Hs.473370.
3D structure databases
HSSP	HSSP built from PDB template 1NB8 based on UniProtKB Q93009.
ProteinModelPortal	Q9HA22.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9HA22.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000007956.
HOVERGEN	HBG068262.
Gene expression databases
ArrayExpress	Q9HA22.
Bgee	Q9HA22.
Family and domain databases
InterPro	IPR018200. Pept_C19ubi-hydrolase_C_CS. IPR001394. Peptidase_C19. [Graphical view]
Pfam	PF00443. UCH. 1 hit. [Graphical view]
PROSITE	PS00973. UCH_2_2. 1 hit. PS50235. UCH_2_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9HA22_HUMAN

Accession

Primary (citable) accession number: Q9HA22

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	May 16, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.