Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized protein C10orf88

Gene

C10orf88

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C10orf88
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:25822. C10orf88.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134993933.

Polymorphism and mutation databases

BioMutaiC10orf88.
DMDMi118572224.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Uncharacterized protein C10orf88PRO_0000260085Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei177 – 1771PhosphoserineCombined sources
Modified residuei182 – 1821PhosphoserineCombined sources
Modified residuei254 – 2541PhosphoserineCombined sources
Modified residuei302 – 3021PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9H8K7.
MaxQBiQ9H8K7.
PaxDbiQ9H8K7.
PeptideAtlasiQ9H8K7.
PRIDEiQ9H8K7.

PTM databases

iPTMnetiQ9H8K7.
PhosphoSiteiQ9H8K7.

Expressioni

Gene expression databases

BgeeiQ9H8K7.
CleanExiHS_C10orf88.
GenevisibleiQ9H8K7. HS.

Organism-specific databases

HPAiHPA039681.
HPA040991.

Interactioni

Protein-protein interaction databases

BioGridi123064. 25 interactions.
IntActiQ9H8K7. 6 interactions.
STRINGi9606.ENSP00000419126.

Structurei

3D structure databases

ProteinModelPortaliQ9H8K7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IFFY. Eukaryota.
ENOG4111YRF. LUCA.
GeneTreeiENSGT00390000017384.
HOGENOMiHOG000111695.
HOVERGENiHBG081190.
InParanoidiQ9H8K7.
OMAiVLDDSEH.
OrthoDBiEOG70S75K.
PhylomeDBiQ9H8K7.
TreeFamiTF333208.

Family and domain databases

InterProiIPR028043. DUF4506.
[Graphical view]
PfamiPF14958. DUF4506. 1 hit.
[Graphical view]
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9H8K7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METRTEDGGL TRRPTLASSW DVAGGALTHS LLLTRAGLGP GDFDWEELLA
60 70 80 90 100
PPAPGQDLVI LKRNHNNKDE NPCFLYLRCG PDGGEEIASI GILSSARNME
110 120 130 140 150
VYLGEEYCGT SRGKNVCTVL DDSEHEKIIL YKKNLKLESS THACKIKLLS
160 170 180 190 200
FGERQCVFIS KVVVHMRSVF ANSSTSSPAL GSRIDLDKVQ TIMESMGSKL
210 220 230 240 250
SPGAQQLMDM VRCQQRNCIP IGEQLQSVLG NSGYKHMIGL QSSSTLGTLN
260 270 280 290 300
KSSSTPFPFR TGLTSGNVTE NLQTYIDKST QLPGGENSTK LDECKVMPQN
310 320 330 340 350
HSFLENDLKN AMASFLPKKV SDNSNIPNSE LLPFLQNLCS QVNHLHVGNK
360 370 380 390 400
TECQENITKH GERILGVGME EQSICSYLEK ILSKNMELME KKLMDYIDQR
410 420 430 440
IHELQEHIDD KIALLLDLLQ NPNSPPTGIP LRHYDSGERL SNGER
Length:445
Mass (Da):49,249
Last modified:November 28, 2006 - v2
Checksum:iD541EA1E400E532B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti67 – 671N → D in BAB14609 (PubMed:14702039).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK023552 mRNA. Translation: BAB14609.1.
BC032645 mRNA. Translation: AAH32645.1.
CCDSiCCDS7632.1.
RefSeqiNP_079218.2. NM_024942.3.
UniGeneiHs.501286.

Genome annotation databases

EnsembliENST00000481909; ENSP00000419126; ENSG00000119965.
GeneIDi80007.
KEGGihsa:80007.
UCSCiuc001lgw.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK023552 mRNA. Translation: BAB14609.1.
BC032645 mRNA. Translation: AAH32645.1.
CCDSiCCDS7632.1.
RefSeqiNP_079218.2. NM_024942.3.
UniGeneiHs.501286.

3D structure databases

ProteinModelPortaliQ9H8K7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123064. 25 interactions.
IntActiQ9H8K7. 6 interactions.
STRINGi9606.ENSP00000419126.

PTM databases

iPTMnetiQ9H8K7.
PhosphoSiteiQ9H8K7.

Polymorphism and mutation databases

BioMutaiC10orf88.
DMDMi118572224.

Proteomic databases

EPDiQ9H8K7.
MaxQBiQ9H8K7.
PaxDbiQ9H8K7.
PeptideAtlasiQ9H8K7.
PRIDEiQ9H8K7.

Protocols and materials databases

DNASUi80007.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000481909; ENSP00000419126; ENSG00000119965.
GeneIDi80007.
KEGGihsa:80007.
UCSCiuc001lgw.3. human.

Organism-specific databases

CTDi80007.
GeneCardsiC10orf88.
HGNCiHGNC:25822. C10orf88.
HPAiHPA039681.
HPA040991.
neXtProtiNX_Q9H8K7.
PharmGKBiPA134993933.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFFY. Eukaryota.
ENOG4111YRF. LUCA.
GeneTreeiENSGT00390000017384.
HOGENOMiHOG000111695.
HOVERGENiHBG081190.
InParanoidiQ9H8K7.
OMAiVLDDSEH.
OrthoDBiEOG70S75K.
PhylomeDBiQ9H8K7.
TreeFamiTF333208.

Miscellaneous databases

ChiTaRSiC10orf88. human.
GenomeRNAii80007.
PROiQ9H8K7.

Gene expression databases

BgeeiQ9H8K7.
CleanExiHS_C10orf88.
GenevisibleiQ9H8K7. HS.

Family and domain databases

InterProiIPR028043. DUF4506.
[Graphical view]
PfamiPF14958. DUF4506. 1 hit.
[Graphical view]
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis and Uterus.
  3. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  4. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-182; SER-254 AND SER-302, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Erythroleukemia.

Entry informationi

Entry nameiCJ088_HUMAN
AccessioniPrimary (citable) accession number: Q9H8K7
Secondary accession number(s): Q0P6C6, Q8N597
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 28, 2006
Last modified: July 6, 2016
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.