Unreviewed, UniProtKB/TrEMBL Q9H8B7 (Q9H8B7_HUMAN)

Names and origin

Protein names	Submitted name:     cDNA FLJ13786 fis, clone PLACE4000654, highly similar to Mus musculus ubiquitin conjugating enzyme EMBL BAB14700.1
Organism	Homo sapiens (Human) EMBL BAB14700.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1867 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family. RuleBase RU004027V3

Ontologies

Gene Ontology (GO)
Biological process	anti-apoptosis Inferred from electronic annotation. Source: Compara positive regulation of cell proliferation Inferred from electronic annotation. Source: Compara post-translational protein modification Inferred from electronic annotation. Source: InterPro regulation of protein metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	membrane fraction Inferred from electronic annotation. Source: Compara
Molecular function	protein binding Inferred from electronic annotation. Source: Compara ubiquitin-protein ligase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9H8B7-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: B4105190F7C1083D	FASTA	1,867	204,150
	10 20 30 40 50 60 MSQILSALGL CNSSAMAMII GASGLHLTKH ENFHGGLDAI SVGDGLFTIL TTLSKKASTV 70 80 90 100 110 120 HMMLQPILTY MACGYMGRQG SLATCQLSEP LLWFILRVLD TSDALKAFHD MGGVQLICNN 130 140 150 160 170 180 MVTSTRAIVN TAKSMVSTIM KFLDSGPNKA VDSTLKTRIL ASEPDNAEGI HNFAPLGTIT 190 200 210 220 230 240 SSSPTAQPAE VLLQATPPHR RARSAAWSYI FLPEEAWCNL TIHLPAAVLL KEIHIQPHLA 250 260 270 280 290 300 SLATCPSSVS VEVSADGVNM LPLSTPVVTS GLTYIKIQLV KAEVASAVCL RLHRPRDAST 310 320 330 340 350 360 LGLSQIKLLG LTAFGTTSSA TVNNPFLPSE DQVSKTSIGW LRLLHHCLTH ISDLEGMMAS 370 380 390 400 410 420 AAAPTANLLQ TCAALLMSPY CGMHSPNIEV VLVKIGLQST RIGLKLIDIL LRNCAASGSD 430 440 450 460 470 480 PTDLNSPLLF GRLNGLSSDS TIDILYQLGT SQDPGTKDRI QALLKWVSDS ARVAAMKRSG 490 500 510 520 530 540 RMNYMCPNSS TVEYGLLMPS PSHLHCVAAI LWHSYELLVE YDLPALLDQE LFELLFNWSM 550 560 570 580 590 600 SLPCNMVLKK AVDSLLCSMC HVHPNYFSLL MGWMGITPPP VQCHHRLSMT DDSKKQDLSS 610 620 630 640 650 660 SLTDDSKNAQ APLALTESHL ATLASSSQSP EAIKQLLDSG LPSLLVRSLA SFCFSHISSS 670 680 690 700 710 720 ESIAQSIDIS QDKLRRHHVP QQCNKMPITA DLVAPILRFL TEVGNSHIMK DWLGGSEVNP 730 740 750 760 770 780 LWTALLFLLC HSGSTSGSHN LGAQQTSARS ASLSSAATTG LTTQQRTAIE NATVAFFLQC 790 800 810 820 830 840 ISCHPNNQKL MAQVLCELFQ TSPQRGNLPT SGNISGFIRR LFLQLMLEDE KVTMFLQSPC 850 860 870 880 890 900 PLYKGRINAT SHVIQHPMYG AGHKFRTLHL PVSTTLSDVL DRVSDTPSIT AKLISEQKDD 910 920 930 940 950 960 KEKKNHEEKE KVKAENGFQD NYSVVVASGL KSQSKRAVSA TPPRPPSRRG RTIPDKIGST 970 980 990 1000 1010 1020 SGAEAANKII TVPVFHLFHK LLAGQPLPAE MTLAQLLTLL YDRKLPQGYR SIDLTVKLGS 1030 1040 1050 1060 1070 1080 RVITDPSLSK TDSYKRLHPE KDHGDLLASC PEDEALTPGD ECMDGILDES LLETCPIQSP 1090 1100 1110 1120 1130 1140 LQVFAGMGGL ALIAERLSML YPEVIQQVSA PVVTSTTLEK PKDSDQFEWV TIEQSGELVY 1150 1160 1170 1180 1190 1200 EAPETVAAEP PPIKSAVQTM SPIPAHSLAA FGLFLRLPGY AEVLLKERKH AQCLLRLVLG 1210 1220 1230 1240 1250 1260 VTDDGEGSHI LQSPSANVLP TLPFHVLRSL FSTTPLTTDD GVLLRRMALE IGALHLILVC 1270 1280 1290 1300 1310 1320 LSALSHHSPR VPNSSVNQTE PQVSSSHNPT STEEQQLYWA KGTGFGTGST ASGWDVEQAL 1330 1340 1350 1360 1370 1380 TKQRLEEEHV TCLLQVLASY INPVSSAVNG EAQSSHETRG QNSNALPSVL LELLSQSCLI 1390 1400 1410 1420 1430 1440 PAMSSYLRND SVLDMARHVP LYRALLELLR AIASCAAMVP LLLPLSTENG EEEEEQSECQ 1450 1460 1470 1480 1490 1500 TSVGTLLAKM KTCVDTYTNR LRSKRENVKT GVKPDASDQE PEGLTLLVPD IQKTAEIVYA 1510 1520 1530 1540 1550 1560 ATTSLRQANQ EKKLGEYSKK AAMKPKPLSV LKSLEEKYVA VMKKLQFDTF EMVSEDEDGK 1570 1580 1590 1600 1610 1620 LGFKVNYHYM SQVKNANDAN SAARARRLAQ EAVTLSTSLP LSSSSSVFVR CDEERLDIMK 1630 1640 1650 1660 1670 1680 VLITGPADTP YANGCFEFDV YFPQDYPSSP PLVNLETTGG HSVRFNPNLY NDGKVCLSIL 1690 1700 1710 1720 1730 1740 NTWHGRPEEK WNPQTSSFLQ VLVSVQSLIL VAEPYFNEPG YERSRGTPSG TQSSREYDGN 1750 1760 1770 1780 1790 1800 IRQATVKWAM LEQIRNPSPC FKEVIHKHFY LKRVEIMAQC EEWIADIQQY SSDKRVGRTM 1810 1820 1830 1840 1850 1860 SHHAAALKRH TAQLREELLK LPCPEDLDPD TDDAPEVCRA TTGAEETLMH DQVKPSSSKE LPSDFQL

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL BAB14700.1.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK023848 mRNA. Translation: BAB14700.1.
IPI	IPI00299635.
UniGene	Hs.150107
3D structure databases
HSSP	HSSP built from PDB template 1JAS based on UniProtKB P23567.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000115760. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:13516. BIRC6.
Phylogenomic databases
HOVERGEN	Q9H8B7.
Gene expression databases
ArrayExpress	Q9H8B7.
Bgee	Q9H8B7.
Family and domain databases
InterPro	IPR016135. UBQ-conjugat/RWD-like. IPR000608. UBQ-conjugat_E2. [Graphical view]
Gene3D	G3DSA:3.10.110.10. UBQ-conjugat_E2. 1 hit.
Pfam	PF00179. UQ_con. 1 hit. [Graphical view]
ProDom	PD000461. UBQ_conjugat. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00212. UBCc. 1 hit. [Graphical view]
PROSITE	PS50127. UBIQUITIN_CONJUGAT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9H8B7_HUMAN

Accession

Primary (citable) accession number: Q9H8B7

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	March 3, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)