ID   DJC18_HUMAN             Reviewed;         358 AA.
AC   Q9H819;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-JAN-2012, entry version 76.
DE   RecName: Full=DnaJ homolog subfamily C member 18;
GN   Name=DNAJC18;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA   Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA   Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA   Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA   Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA   Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA   Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA   Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA   Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA   Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA   Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA   Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA   Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA   Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA   Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA   Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA   Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA   Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA   Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA   Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Muscle;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein
CC       (Potential).
CC   -!- SIMILARITY: Contains 1 J domain.
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DR   EMBL; AK024054; BAB14804.1; -; mRNA.
DR   EMBL; BC030162; AAH30162.1; -; mRNA.
DR   IPI; IPI00025510; -.
DR   RefSeq; NP_689899.1; NM_152686.3.
DR   UniGene; Hs.483537; -.
DR   ProteinModelPortal; Q9H819; -.
DR   SMR; Q9H819; 80-176.
DR   PhosphoSite; Q9H819; -.
DR   DMDM; 74733748; -.
DR   PRIDE; Q9H819; -.
DR   Ensembl; ENST00000302060; ENSP00000302843; ENSG00000170464.
DR   GeneID; 202052; -.
DR   KEGG; hsa:202052; -.
DR   UCSC; uc003len.1; human.
DR   CTD; 202052; -.
DR   GeneCards; GC05M138776; -.
DR   HGNC; HGNC:28429; DNAJC18.
DR   HPA; HPA036538; -.
DR   neXtProt; NX_Q9H819; -.
DR   PharmGKB; PA142671966; -.
DR   eggNOG; prNOG09729; -.
DR   GeneTree; ENSGT00550000074587; -.
DR   HOGENOM; HBG737361; -.
DR   HOVERGEN; HBG051373; -.
DR   InParanoid; Q9H819; -.
DR   OMA; PRARPYN; -.
DR   OrthoDB; EOG41G34F; -.
DR   PhylomeDB; Q9H819; -.
DR   NextBio; 90244; -.
DR   ArrayExpress; Q9H819; -.
DR   Bgee; Q9H819; -.
DR   CleanEx; HS_DNAJC18; -.
DR   Genevestigator; Q9H819; -.
DR   GermOnline; ENSG00000170464; Homo sapiens.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031072; F:heat shock protein binding; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   InterPro; IPR001623; DnaJ_N.
DR   InterPro; IPR015399; DUF1977_DnaJ-like.
DR   InterPro; IPR018253; Heat_shock_DnaJ_CS.
DR   InterPro; IPR003095; Hsp_DnaJ.
DR   Gene3D; G3DSA:1.10.287.110; DnaJ_N; 1.
DR   KO; K09538; -.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF09320; DUF1977; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; DnaJ_N; 1.
DR   PROSITE; PS00636; DNAJ_1; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Complete proteome; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN         1    358       DnaJ homolog subfamily C member 18.
FT                                /FTId=PRO_0000244085.
FT   TRANSMEM    228    248       Helical; (Potential).
FT   DOMAIN       82    146       J.
FT   COMPBIAS    216    220       Poly-Glu.
SQ   SEQUENCE   358 AA;  41551 MW;  BF8864DAB6D7695A CRC64;
     MAATLGSGER WTEAYIDAVR RNKYPEDTPP ESHDPCGCCN CMKAQKEKKS ENEWTQTRQG
     EGNSTYSEEQ LLGVQRIKKC RNYYEILGVS RDASDEELKK AYRKLALKFH PDKNCAPGAT
     DAFKAIGNAF AVLSNPDKRL RYDEYGDEQV TFTAPRARPY NYYRDFEADI TPEELFNVFF
     GGHFPTGNIH MFSNVTDDTY YYRRRHRHER TQTQKEEEEE KPQTTYSAFI QLLPVLVIVI
     ISVITQLLAT NPPYSLFYKS TLGYTISRET QNLQVPYFVD KNFDKAYRGA SLHDLEKTIE
     KDYIDYIQTS CWKEKQQKSE LTNLAGLYRD ERLKQKAESL KLENCEKLSK LIGLRRGG
//