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Reviewed, UniProtKB/Swiss-Prot Q9H819 (DJC18_HUMAN)

Last modified November 3, 2009. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    DnaJ homolog subfamily C member 18
Gene names
Name: DNAJC18
OrganismHomo sapiens (Human) [Complete proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Contains 1 J domain.

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Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processprotein folding

Inferred from electronic annotation. Source: InterPro

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionheat shock protein binding

Inferred from electronic annotation. Source: InterPro

unfolded protein binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 358358DnaJ homolog subfamily C member 18
PRO_0000244085

Regions

Transmembrane228 – 24821 Potential
Domain82 – 14665J
Compositional bias216 – 2205Poly-Glu

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Sequences

Sequence LengthMass (Da)Tools
Q9H819-1 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: BF8864DAB6D7695A

FASTA35841,551
        10         20         30         40         50         60 
MAATLGSGER WTEAYIDAVR RNKYPEDTPP ESHDPCGCCN CMKAQKEKKS ENEWTQTRQG 

        70         80         90        100        110        120 
EGNSTYSEEQ LLGVQRIKKC RNYYEILGVS RDASDEELKK AYRKLALKFH PDKNCAPGAT 

       130        140        150        160        170        180 
DAFKAIGNAF AVLSNPDKRL RYDEYGDEQV TFTAPRARPY NYYRDFEADI TPEELFNVFF 

       190        200        210        220        230        240 
GGHFPTGNIH MFSNVTDDTY YYRRRHRHER TQTQKEEEEE KPQTTYSAFI QLLPVLVIVI 

       250        260        270        280        290        300 
ISVITQLLAT NPPYSLFYKS TLGYTISRET QNLQVPYFVD KNFDKAYRGA SLHDLEKTIE 

       310        320        330        340        350 
KDYIDYIQTS CWKEKQQKSE LTNLAGLYRD ERLKQKAESL KLENCEKLSK LIGLRRGG

« Hide

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References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Muscle.

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Cross-references

Sequence databases

AK024054 mRNA. Translation: BAB14804.1.
BC030162 mRNA. Translation: AAH30162.1.
IPIIPI00025510.
RefSeqNP_689899.1.
UniGeneHs.483537

3D structure databases

HSSPHSSP built from PDB template 1HDJ based on UniProtKB P25685.
SMRQ9H819. Positions 82-146.
ModBaseSearch...

Proteomic databases

PRIDEQ9H819.

Genome annotation databases

EnsemblENST00000302060; ENSP00000302843; ENSG00000170464; Homo sapiens. [Genome view]
GeneID202052.
KEGGhsa:202052.
UCSCuc003len.1. human.

Organism-specific databases

CTD202052.
GeneCardsGC05M138776.
HGNCHGNC:28429. DNAJC18.
PharmGKBPA142671966.
GenAtlasSearch...

Phylogenomic databases

HOGENOMQ9H819.
HOVERGENQ9H819.
OMAPRARPYN.

Gene expression databases

ArrayExpressQ9H819.
BgeeQ9H819.
CleanExHS_DNAJC18.
GenevestigatorQ9H819.
GermOnlineENSG00000170464. Homo sapiens.

Family and domain databases

InterProIPR001623. DnaJ_N.
IPR015399. DUF1977_DnaJ-like.
IPR018253. Heat_shock_DnaJ_CS.
IPR015609. Hsp40/DnaJ_Rel.
IPR003095. Hsp_DnaJ.
[Graphical view]
Gene3DG3DSA:1.10.287.110. DnaJ_N. 1 hit.
PANTHERPTHR11821. Hsp40/DnaJ_Rel. 1 hit.
PfamPF00226. DnaJ. 1 hit.
PF09320. DUF1977. 1 hit.
[Graphical view]
PRINTSPR00625. DNAJPROTEIN.
SMARTSM00271. DnaJ. 1 hit.
[Graphical view]
PROSITEPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio90244.

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Entry information

Entry nameDJC18_HUMAN
AccessionPrimary (citable) accession number: Q9H819
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 1, 2001
Last modified: November 3, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents