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Q9H7M6

- ZSWM4_HUMAN

UniProt

Q9H7M6 - ZSWM4_HUMAN

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Protein
Zinc finger SWIM domain-containing protein 4
Gene
ZSWIM4
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri139 – 17638SWIM-type
Add
BLAST

GO - Molecular functioni

  1. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger SWIM domain-containing protein 4
Gene namesi
Name:ZSWIM4
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:25704. ZSWIM4.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134975055.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 989989Zinc finger SWIM domain-containing protein 4
PRO_0000223101Add
BLAST

Proteomic databases

PaxDbiQ9H7M6.
PRIDEiQ9H7M6.

PTM databases

PhosphoSiteiQ9H7M6.

Expressioni

Gene expression databases

ArrayExpressiQ9H7M6.
BgeeiQ9H7M6.
CleanExiHS_ZSWIM4.
GenevestigatoriQ9H7M6.

Organism-specific databases

HPAiHPA042084.

Interactioni

Protein-protein interaction databases

BioGridi122412. 1 interaction.
STRINGi9606.ENSP00000254323.

Structurei

3D structure databases

ProteinModelPortaliQ9H7M6.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiNOG322060.
HOGENOMiHOG000231419.
HOVERGENiHBG058098.
InParanoidiQ9H7M6.
OMAiLYHVSIS.
OrthoDBiEOG74J970.
PhylomeDBiQ9H7M6.
TreeFamiTF324881.

Family and domain databases

InterProiIPR007527. Znf_SWIM.
[Graphical view]
PROSITEiPS50966. ZF_SWIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9H7M6-1 [UniParc]FASTAAdd to Basket

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MEPPAAKRSR GCPAGPEERD AGAGAARGRG RPEALLDLSA KRVAESWAFE    50
QVEERFSRVP EPVQKRIVFW SFPRSEREIC MYSSLGYPPP EGEHDARVPF 100
TRGLHLLQSG AVDRVLQVGF HLSGNIREPG SPGEPERLYH VSISFDRCKI 150
TSVSCGCDNR DLFYCAHVVA LSLYRIRHAH QVELRLPISE TLSQMNRDQL 200
QKFVQYLISA HHTEVLPTAQ RLADEILLLG SEINLVNGAP DPTAGAGIED 250
ANCWHLDEEQ IQEQVKQLLS NGGYYGASQQ LRSMFSKVRE MLRMRDSNGA 300
RMLILMTEQF LQDTRLALWR QQGAGMTDKC RQLWDELGAL WVCVVLSPHC 350
KPEERAGWLQ LLSRWDKLDV CPLEEGNYSF DGPSLQPTMA PAPELLQKGS 400
TCITNTEGWV GHPLDPIGCL CRALLEACRL EEETLTLYPD SGPEKRKVAY 450
QHVPVPGSPG ESYLVLALEV ALLGLGQQRA LPEGLYAQDK VVRNEEQLLA 500
LLEEVELDER LVQVLRKQAG LLLEGGPFSG FGEVLFRESV PMHTCARYLF 550
TALLPHDPDL AYRLALRAMR LPILETAFPA GEPHPSPLDS IMSNRFPRWF 600
ILGHLETRQC ELASTMLTAA KGDPKWLHTV LGSIQQNIHS PALLFKLAQD 650
ACKTATPVSA PPDTTLLGIA LELGLQVMRM TLNVMTWRRR EMVRWLVSCA 700
TEIGPQALMN IMQNWYSLFT PVEAATIVAV TGTTHATLLR LQLDTSRREE 750
LWACARTLAL QCAMKDPQNC ALPALTLCEK NHSAFEAAYQ IVLDAAAGGL 800
GHAHLFTVAR YMEHRGLPLR AYKLATLALA QLSIAFNQDS HPAVNDVLWA 850
CSLSHSLGRH ELSAIVPLII RSIHCAPMLS DILRRWTLSA PGLGPLGARR 900
AAKPLGADRA PLCQLLDAAV TAYITTSHSR LTHISPRHYG DFIEFLGKAR 950
ETFLLAPDGH LQFSQFLENL KQTYKGKKKL MLLVRERFG 989
Length:989
Mass (Da):110,138
Last modified:May 18, 2010 - v3
Checksum:i1BFDAF8291131A2D
GO

Sequence cautioni

The sequence BAB15742.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti629 – 6291T → M in BAB15742. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024452 mRNA. Translation: BAB15742.1. Different initiation.
AC020916 Genomic DNA. No translation available.
CCDSiCCDS32924.1.
RefSeqiNP_075560.2. NM_023072.2.
UniGeneiHs.466015.

Genome annotation databases

EnsembliENST00000254323; ENSP00000254323; ENSG00000132003.
GeneIDi65249.
KEGGihsa:65249.
UCSCiuc002mxh.1. human.

Polymorphism databases

DMDMi296453063.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024452 mRNA. Translation: BAB15742.1 . Different initiation.
AC020916 Genomic DNA. No translation available.
CCDSi CCDS32924.1.
RefSeqi NP_075560.2. NM_023072.2.
UniGenei Hs.466015.

3D structure databases

ProteinModelPortali Q9H7M6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 122412. 1 interaction.
STRINGi 9606.ENSP00000254323.

PTM databases

PhosphoSitei Q9H7M6.

Polymorphism databases

DMDMi 296453063.

Proteomic databases

PaxDbi Q9H7M6.
PRIDEi Q9H7M6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000254323 ; ENSP00000254323 ; ENSG00000132003 .
GeneIDi 65249.
KEGGi hsa:65249.
UCSCi uc002mxh.1. human.

Organism-specific databases

CTDi 65249.
GeneCardsi GC19P013906.
HGNCi HGNC:25704. ZSWIM4.
HPAi HPA042084.
neXtProti NX_Q9H7M6.
PharmGKBi PA134975055.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG322060.
HOGENOMi HOG000231419.
HOVERGENi HBG058098.
InParanoidi Q9H7M6.
OMAi LYHVSIS.
OrthoDBi EOG74J970.
PhylomeDBi Q9H7M6.
TreeFami TF324881.

Miscellaneous databases

GenomeRNAii 65249.
NextBioi 67367.
PROi Q9H7M6.

Gene expression databases

ArrayExpressi Q9H7M6.
Bgeei Q9H7M6.
CleanExi HS_ZSWIM4.
Genevestigatori Q9H7M6.

Family and domain databases

InterProi IPR007527. Znf_SWIM.
[Graphical view ]
PROSITEi PS50966. ZF_SWIM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Characterization of long cDNA clones from human adult spleen."
    Hattori A., Okumura K., Nagase T., Kikuno R., Hirosawa M., Ohara O.
    DNA Res. 7:357-366(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Spleen.
  2. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiZSWM4_HUMAN
AccessioniPrimary (citable) accession number: Q9H7M6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: May 18, 2010
Last modified: July 9, 2014
This is version 81 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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