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Q9H7M6 (ZSWM4_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger SWIM domain-containing protein 4
Gene names
Name:ZSWIM4
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length989 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SWIM-type zinc finger.

Sequence caution

The sequence BAB15742.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
   DomainZinc-finger
   LigandMetal-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionzinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 989989Zinc finger SWIM domain-containing protein 4
PRO_0000223101

Regions

Zinc finger139 – 17638SWIM-type

Experimental info

Sequence conflict6291T → M in BAB15742. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9H7M6 [UniParc].

Last modified May 18, 2010. Version 3.
Checksum: 1BFDAF8291131A2D

FASTA989110,138
        10         20         30         40         50         60 
MEPPAAKRSR GCPAGPEERD AGAGAARGRG RPEALLDLSA KRVAESWAFE QVEERFSRVP 

        70         80         90        100        110        120 
EPVQKRIVFW SFPRSEREIC MYSSLGYPPP EGEHDARVPF TRGLHLLQSG AVDRVLQVGF 

       130        140        150        160        170        180 
HLSGNIREPG SPGEPERLYH VSISFDRCKI TSVSCGCDNR DLFYCAHVVA LSLYRIRHAH 

       190        200        210        220        230        240 
QVELRLPISE TLSQMNRDQL QKFVQYLISA HHTEVLPTAQ RLADEILLLG SEINLVNGAP 

       250        260        270        280        290        300 
DPTAGAGIED ANCWHLDEEQ IQEQVKQLLS NGGYYGASQQ LRSMFSKVRE MLRMRDSNGA 

       310        320        330        340        350        360 
RMLILMTEQF LQDTRLALWR QQGAGMTDKC RQLWDELGAL WVCVVLSPHC KPEERAGWLQ 

       370        380        390        400        410        420 
LLSRWDKLDV CPLEEGNYSF DGPSLQPTMA PAPELLQKGS TCITNTEGWV GHPLDPIGCL 

       430        440        450        460        470        480 
CRALLEACRL EEETLTLYPD SGPEKRKVAY QHVPVPGSPG ESYLVLALEV ALLGLGQQRA 

       490        500        510        520        530        540 
LPEGLYAQDK VVRNEEQLLA LLEEVELDER LVQVLRKQAG LLLEGGPFSG FGEVLFRESV 

       550        560        570        580        590        600 
PMHTCARYLF TALLPHDPDL AYRLALRAMR LPILETAFPA GEPHPSPLDS IMSNRFPRWF 

       610        620        630        640        650        660 
ILGHLETRQC ELASTMLTAA KGDPKWLHTV LGSIQQNIHS PALLFKLAQD ACKTATPVSA 

       670        680        690        700        710        720 
PPDTTLLGIA LELGLQVMRM TLNVMTWRRR EMVRWLVSCA TEIGPQALMN IMQNWYSLFT 

       730        740        750        760        770        780 
PVEAATIVAV TGTTHATLLR LQLDTSRREE LWACARTLAL QCAMKDPQNC ALPALTLCEK 

       790        800        810        820        830        840 
NHSAFEAAYQ IVLDAAAGGL GHAHLFTVAR YMEHRGLPLR AYKLATLALA QLSIAFNQDS 

       850        860        870        880        890        900 
HPAVNDVLWA CSLSHSLGRH ELSAIVPLII RSIHCAPMLS DILRRWTLSA PGLGPLGARR 

       910        920        930        940        950        960 
AAKPLGADRA PLCQLLDAAV TAYITTSHSR LTHISPRHYG DFIEFLGKAR ETFLLAPDGH 

       970        980 
LQFSQFLENL KQTYKGKKKL MLLVRERFG 

« Hide

References

[1]"Characterization of long cDNA clones from human adult spleen."
Hattori A., Okumura K., Nagase T., Kikuno R., Hirosawa M., Ohara O.
DNA Res. 7:357-366(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Spleen.
[2]"The DNA sequence and biology of human chromosome 19."
Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V. expand/collapse author list , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK024452 mRNA. Translation: BAB15742.1. Different initiation.
AC020916 Genomic DNA. No translation available.
RefSeqNP_075560.2. NM_023072.2.
UniGeneHs.466015.

3D structure databases

ProteinModelPortalQ9H7M6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122412. 1 interaction.
STRING9606.ENSP00000254323.

PTM databases

PhosphoSiteQ9H7M6.

Polymorphism databases

DMDM296453063.

Proteomic databases

PaxDbQ9H7M6.
PRIDEQ9H7M6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000254323; ENSP00000254323; ENSG00000132003.
GeneID65249.
KEGGhsa:65249.
UCSCuc002mxh.1. human.

Organism-specific databases

CTD65249.
GeneCardsGC19P013906.
HGNCHGNC:25704. ZSWIM4.
HPAHPA042084.
neXtProtNX_Q9H7M6.
PharmGKBPA134975055.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG322060.
HOGENOMHOG000231419.
HOVERGENHBG058098.
InParanoidQ9H7M6.
OMAYHVSISF.
OrthoDBEOG74J970.
PhylomeDBQ9H7M6.
TreeFamTF324881.

Gene expression databases

ArrayExpressQ9H7M6.
BgeeQ9H7M6.
CleanExHS_ZSWIM4.
GenevestigatorQ9H7M6.

Family and domain databases

InterProIPR007527. Znf_SWIM.
[Graphical view]
PROSITEPS50966. ZF_SWIM. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi65249.
NextBio67367.
PROQ9H7M6.

Entry information

Entry nameZSWM4_HUMAN
AccessionPrimary (citable) accession number: Q9H7M6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: May 18, 2010
Last modified: April 16, 2014
This is version 79 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 19

Human chromosome 19: entries, gene names and cross-references to MIM