Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9H7M6

- ZSWM4_HUMAN

UniProt

Q9H7M6 - ZSWM4_HUMAN

Protein

Zinc finger SWIM domain-containing protein 4

Gene

ZSWIM4

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 3 (18 May 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri139 – 17638SWIM-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. zinc ion binding Source: InterPro

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Zinc finger SWIM domain-containing protein 4
    Gene namesi
    Name:ZSWIM4
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:25704. ZSWIM4.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134975055.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 989989Zinc finger SWIM domain-containing protein 4PRO_0000223101Add
    BLAST

    Proteomic databases

    PaxDbiQ9H7M6.
    PRIDEiQ9H7M6.

    PTM databases

    PhosphoSiteiQ9H7M6.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9H7M6.
    BgeeiQ9H7M6.
    CleanExiHS_ZSWIM4.
    GenevestigatoriQ9H7M6.

    Organism-specific databases

    HPAiHPA042084.

    Interactioni

    Protein-protein interaction databases

    BioGridi122412. 1 interaction.
    STRINGi9606.ENSP00000254323.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9H7M6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SWIM-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri139 – 17638SWIM-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiNOG322060.
    HOGENOMiHOG000231419.
    HOVERGENiHBG058098.
    InParanoidiQ9H7M6.
    OMAiLYHVSIS.
    OrthoDBiEOG74J970.
    PhylomeDBiQ9H7M6.
    TreeFamiTF324881.

    Family and domain databases

    InterProiIPR007527. Znf_SWIM.
    [Graphical view]
    PROSITEiPS50966. ZF_SWIM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9H7M6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEPPAAKRSR GCPAGPEERD AGAGAARGRG RPEALLDLSA KRVAESWAFE    50
    QVEERFSRVP EPVQKRIVFW SFPRSEREIC MYSSLGYPPP EGEHDARVPF 100
    TRGLHLLQSG AVDRVLQVGF HLSGNIREPG SPGEPERLYH VSISFDRCKI 150
    TSVSCGCDNR DLFYCAHVVA LSLYRIRHAH QVELRLPISE TLSQMNRDQL 200
    QKFVQYLISA HHTEVLPTAQ RLADEILLLG SEINLVNGAP DPTAGAGIED 250
    ANCWHLDEEQ IQEQVKQLLS NGGYYGASQQ LRSMFSKVRE MLRMRDSNGA 300
    RMLILMTEQF LQDTRLALWR QQGAGMTDKC RQLWDELGAL WVCVVLSPHC 350
    KPEERAGWLQ LLSRWDKLDV CPLEEGNYSF DGPSLQPTMA PAPELLQKGS 400
    TCITNTEGWV GHPLDPIGCL CRALLEACRL EEETLTLYPD SGPEKRKVAY 450
    QHVPVPGSPG ESYLVLALEV ALLGLGQQRA LPEGLYAQDK VVRNEEQLLA 500
    LLEEVELDER LVQVLRKQAG LLLEGGPFSG FGEVLFRESV PMHTCARYLF 550
    TALLPHDPDL AYRLALRAMR LPILETAFPA GEPHPSPLDS IMSNRFPRWF 600
    ILGHLETRQC ELASTMLTAA KGDPKWLHTV LGSIQQNIHS PALLFKLAQD 650
    ACKTATPVSA PPDTTLLGIA LELGLQVMRM TLNVMTWRRR EMVRWLVSCA 700
    TEIGPQALMN IMQNWYSLFT PVEAATIVAV TGTTHATLLR LQLDTSRREE 750
    LWACARTLAL QCAMKDPQNC ALPALTLCEK NHSAFEAAYQ IVLDAAAGGL 800
    GHAHLFTVAR YMEHRGLPLR AYKLATLALA QLSIAFNQDS HPAVNDVLWA 850
    CSLSHSLGRH ELSAIVPLII RSIHCAPMLS DILRRWTLSA PGLGPLGARR 900
    AAKPLGADRA PLCQLLDAAV TAYITTSHSR LTHISPRHYG DFIEFLGKAR 950
    ETFLLAPDGH LQFSQFLENL KQTYKGKKKL MLLVRERFG 989
    Length:989
    Mass (Da):110,138
    Last modified:May 18, 2010 - v3
    Checksum:i1BFDAF8291131A2D
    GO

    Sequence cautioni

    The sequence BAB15742.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti629 – 6291T → M in BAB15742. (PubMed:11214971)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK024452 mRNA. Translation: BAB15742.1. Different initiation.
    AC020916 Genomic DNA. No translation available.
    CCDSiCCDS32924.1.
    RefSeqiNP_075560.2. NM_023072.2.
    UniGeneiHs.466015.

    Genome annotation databases

    EnsembliENST00000254323; ENSP00000254323; ENSG00000132003.
    GeneIDi65249.
    KEGGihsa:65249.
    UCSCiuc002mxh.1. human.

    Polymorphism databases

    DMDMi296453063.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK024452 mRNA. Translation: BAB15742.1 . Different initiation.
    AC020916 Genomic DNA. No translation available.
    CCDSi CCDS32924.1.
    RefSeqi NP_075560.2. NM_023072.2.
    UniGenei Hs.466015.

    3D structure databases

    ProteinModelPortali Q9H7M6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 122412. 1 interaction.
    STRINGi 9606.ENSP00000254323.

    PTM databases

    PhosphoSitei Q9H7M6.

    Polymorphism databases

    DMDMi 296453063.

    Proteomic databases

    PaxDbi Q9H7M6.
    PRIDEi Q9H7M6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000254323 ; ENSP00000254323 ; ENSG00000132003 .
    GeneIDi 65249.
    KEGGi hsa:65249.
    UCSCi uc002mxh.1. human.

    Organism-specific databases

    CTDi 65249.
    GeneCardsi GC19P013906.
    HGNCi HGNC:25704. ZSWIM4.
    HPAi HPA042084.
    neXtProti NX_Q9H7M6.
    PharmGKBi PA134975055.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG322060.
    HOGENOMi HOG000231419.
    HOVERGENi HBG058098.
    InParanoidi Q9H7M6.
    OMAi LYHVSIS.
    OrthoDBi EOG74J970.
    PhylomeDBi Q9H7M6.
    TreeFami TF324881.

    Miscellaneous databases

    GenomeRNAii 65249.
    NextBioi 67367.
    PROi Q9H7M6.

    Gene expression databases

    ArrayExpressi Q9H7M6.
    Bgeei Q9H7M6.
    CleanExi HS_ZSWIM4.
    Genevestigatori Q9H7M6.

    Family and domain databases

    InterProi IPR007527. Znf_SWIM.
    [Graphical view ]
    PROSITEi PS50966. ZF_SWIM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of long cDNA clones from human adult spleen."
      Hattori A., Okumura K., Nagase T., Kikuno R., Hirosawa M., Ohara O.
      DNA Res. 7:357-366(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Spleen.
    2. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiZSWM4_HUMAN
    AccessioniPrimary (citable) accession number: Q9H7M6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 16, 2004
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 82 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3