Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9H7E9

- CH033_HUMAN

UniProt

Q9H7E9 - CH033_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

UPF0488 protein C8orf33

Gene

C8orf33

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0488 protein C8orf33
Gene namesi
Name:C8orf33
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 8

Organism-specific databases

HGNCiHGNC:26104. C8orf33.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672352.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 229228UPF0488 protein C8orf33PRO_0000304982Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine1 Publication
Modified residuei82 – 821Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ9H7E9.
PaxDbiQ9H7E9.
PRIDEiQ9H7E9.

PTM databases

PhosphoSiteiQ9H7E9.

Expressioni

Gene expression databases

BgeeiQ9H7E9.
CleanExiHS_C8orf33.
GenevestigatoriQ9H7E9.

Organism-specific databases

HPAiHPA024812.
HPA026104.

Interactioni

Protein-protein interaction databases

BioGridi122420. 40 interactions.
IntActiQ9H7E9. 35 interactions.
MINTiMINT-1396236.
STRINGi9606.ENSP00000330361.

Structurei

3D structure databases

ProteinModelPortaliQ9H7E9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0488 family.Curated

Phylogenomic databases

eggNOGiNOG76812.
GeneTreeiENSGT00390000000306.
HOGENOMiHOG000111613.
HOVERGENiHBG097250.
InParanoidiQ9H7E9.
OMAiSQRVCRP.
OrthoDBiEOG7RV9HN.
PhylomeDBiQ9H7E9.
TreeFamiTF326272.

Family and domain databases

InterProiIPR029274. DUF4615.
[Graphical view]
PfamiPF15393. DUF4615. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9H7E9-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAALGHLAGE AAAAPGPGTP CASRGARLPG PVSSARNPST VCLCPEQPTC
60 70 80 90 100
SNADSRAHPL GDEGGTASKK QKNKKKTRNR ASVANGGEKA SEKLAPEEVP
110 120 130 140 150
LSAEAQAQQL AQELAWCVEQ LELGLKRQKP TPKQKEQAIG AIRTLRSKRT
160 170 180 190 200
PLPRKRQLMH SLFGDYRAQM EAEWREALRA LRAAAYSAQV QPVDGATRKK
210 220
SQRVCRPRSI WRAKATLDMP DEEFRFNFF
Length:229
Mass (Da):24,993
Last modified:March 1, 2001 - v1
Checksum:iEFAFCF3ED552AC45
GO
Isoform 2 (identifier: Q9H7E9-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     106-106: Q → QARAGFGREGWNPR

Note: No experimental confirmation available.

Show »
Length:242
Mass (Da):26,448
Checksum:iEA75900805D43331
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei106 – 1061Q → QARAGFGREGWNPR in isoform 2. 1 PublicationVSP_028169

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024642 mRNA. Translation: BAB14943.1.
CR457330 mRNA. Translation: CAG33611.1.
AC139103 Genomic DNA. No translation available.
CH471162 Genomic DNA. Translation: EAW82023.1.
BC010001 mRNA. Translation: AAH10001.1.
BC015181 mRNA. Translation: AAH15181.1.
CCDSiCCDS34974.1. [Q9H7E9-1]
RefSeqiNP_075568.1. NM_023080.2. [Q9H7E9-1]
UniGeneiHs.169615.

Genome annotation databases

EnsembliENST00000331434; ENSP00000330361; ENSG00000182307. [Q9H7E9-1]
GeneIDi65265.
KEGGihsa:65265.
UCSCiuc003zfc.4. human. [Q9H7E9-1]

Polymorphism databases

DMDMi74733630.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024642 mRNA. Translation: BAB14943.1 .
CR457330 mRNA. Translation: CAG33611.1 .
AC139103 Genomic DNA. No translation available.
CH471162 Genomic DNA. Translation: EAW82023.1 .
BC010001 mRNA. Translation: AAH10001.1 .
BC015181 mRNA. Translation: AAH15181.1 .
CCDSi CCDS34974.1. [Q9H7E9-1 ]
RefSeqi NP_075568.1. NM_023080.2. [Q9H7E9-1 ]
UniGenei Hs.169615.

3D structure databases

ProteinModelPortali Q9H7E9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 122420. 40 interactions.
IntActi Q9H7E9. 35 interactions.
MINTi MINT-1396236.
STRINGi 9606.ENSP00000330361.

PTM databases

PhosphoSitei Q9H7E9.

Polymorphism databases

DMDMi 74733630.

Proteomic databases

MaxQBi Q9H7E9.
PaxDbi Q9H7E9.
PRIDEi Q9H7E9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000331434 ; ENSP00000330361 ; ENSG00000182307 . [Q9H7E9-1 ]
GeneIDi 65265.
KEGGi hsa:65265.
UCSCi uc003zfc.4. human. [Q9H7E9-1 ]

Organism-specific databases

CTDi 65265.
GeneCardsi GC08P146249.
H-InvDB HIX0019175.
HGNCi HGNC:26104. C8orf33.
HPAi HPA024812.
HPA026104.
neXtProti NX_Q9H7E9.
PharmGKBi PA142672352.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG76812.
GeneTreei ENSGT00390000000306.
HOGENOMi HOG000111613.
HOVERGENi HBG097250.
InParanoidi Q9H7E9.
OMAi SQRVCRP.
OrthoDBi EOG7RV9HN.
PhylomeDBi Q9H7E9.
TreeFami TF326272.

Miscellaneous databases

GenomeRNAii 65265.
NextBioi 67394.

Gene expression databases

Bgeei Q9H7E9.
CleanExi HS_C8orf33.
Genevestigatori Q9H7E9.

Family and domain databases

InterProi IPR029274. DUF4615.
[Graphical view ]
Pfami PF15393. DUF4615. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Endothelial cell.
  2. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  3. "DNA sequence and analysis of human chromosome 8."
    Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
    , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
    Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 76-229 (ISOFORM 2).
    Tissue: Brain and Uterus.
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-82, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiCH033_HUMAN
AccessioniPrimary (citable) accession number: Q9H7E9
Secondary accession number(s): A6NGC0, Q96BT8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3