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Q9H792 (PEAK1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 108. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (6) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pseudopodium-enriched atypical kinase 1

EC=2.7.10.2
Alternative name(s):
Sugen kinase 269
Tyrosine-protein kinase SgK269
Gene names
Name:PEAK1
Synonyms:KIAA2002
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1746 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN. Ref.9

Catalytic activity

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. Ref.9

Subunit structure

Interacts with BCAR1 and CRK. Ref.9

Subcellular location

Cytoplasmcytoskeleton. Cell junctionfocal adhesion. Note: Colocalizes with F-actin in serum-rich medium. Actin colocalization is reduced during serum starvation. Ref.9

Post-translational modification

Phosphorylated on tyrosine in a CSK-dependent manner in response to adhesion to fibronectin and to EGF stimulation. Autophosphorylated in vitro. Ref.9

Sequence similarities

Belongs to the protein kinase superfamily.

Contains 1 protein kinase domain.

Sequence caution

The sequence BAB15006.1 differs from that shown. Reason: Erroneous initiation.

The sequence BAC87076.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 17461746Pseudopodium-enriched atypical kinase 1
PRO_0000250589

Regions

Domain1313 – 1675363Protein kinase
Nucleotide binding1319 – 13279ATP By similarity
Compositional bias117 – 1204Poly-Asn
Compositional bias324 – 40683Ser-rich
Compositional bias500 – 5034Poly-Ser
Compositional bias776 – 87398Pro-rich
Compositional bias964 – 9674Poly-Pro

Sites

Active site15161Proton acceptor By similarity
Binding site13591ATP By similarity

Amino acid modifications

Modified residue2811Phosphoserine Ref.11
Modified residue5401Phosphoserine Ref.7
Modified residue5871Phosphoserine Ref.7
Modified residue6351Phosphotyrosine Ref.11
Modified residue6411Phosphotyrosine By similarity

Natural variations

Natural variant2131G → R. Ref.12
Corresponds to variant rs35459975 [ dbSNP | Ensembl ].
VAR_041817
Natural variant2401V → I. Ref.12
Corresponds to variant rs56129428 [ dbSNP | Ensembl ].
VAR_041818
Natural variant4401S → P. Ref.12
Corresponds to variant rs35335169 [ dbSNP | Ensembl ].
VAR_041819
Natural variant6111H → Q in a bladder carcinoma NOS sample; somatic mutation. Ref.12
VAR_041820
Natural variant7921S → I. Ref.12
Corresponds to variant rs34885462 [ dbSNP | Ensembl ].
VAR_041821
Natural variant8361D → E. Ref.12
Corresponds to variant rs56388121 [ dbSNP | Ensembl ].
VAR_041822
Natural variant10351S → F in a metastatic melanoma sample; somatic mutation. Ref.12
VAR_041823
Natural variant10711R → K. Ref.12
Corresponds to variant rs12909704 [ dbSNP | Ensembl ].
VAR_041824
Natural variant10771T → P. Ref.12
Corresponds to variant rs56133554 [ dbSNP | Ensembl ].
VAR_041825
Natural variant11451P → L in a metastatic melanoma sample; somatic mutation. Ref.12
VAR_041826
Natural variant14081P → Q. Ref.12
Corresponds to variant rs56079860 [ dbSNP | Ensembl ].
VAR_041827
Natural variant15421S → T. Ref.12
Corresponds to variant rs1867780 [ dbSNP | Ensembl ].
VAR_041828
Natural variant16991R → G. Ref.12
Corresponds to variant rs34004337 [ dbSNP | Ensembl ].
VAR_041829

Experimental info

Sequence conflict7791S → F in BAC87076. Ref.2
Sequence conflict1046 – 10494SHMT → RYVK in AK091802. Ref.2
Sequence conflict1112 – 11209QSRAAMIPP → KCKCPISSI in BAB84983. Ref.3
Sequence conflict1375 – 13784LAVR → SQEF in BAC87076. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9H792 [UniParc].

Last modified February 10, 2009. Version 4.
Checksum: 7C9A9F60BBCF6C61

FASTA1,746193,106
        10         20         30         40         50         60 
MSACNTFTEH VWKPGECKNC FKPKSLHQLP PDPEKAPITH GNVKTNANHS NNHRIRNTGN 

        70         80         90        100        110        120 
FRPPVAKKPT IAVKPTMIVA DGQSICGELS IQEHCENKPV IIGWNRNRAA LSQKPLNNNN 

       130        140        150        160        170        180 
EDDEGISHVP KPYGNNDSAK KMSDNNNGLT EVLKEIAGLD TAPQIRGNET NSRETFLGRI 

       190        200        210        220        230        240 
NDCYKRSLER KLPPSCMIGG IKETQGKHVI LSGSTEVISN EGGRFCYPEF SSGEESEEDV 

       250        260        270        280        290        300 
LFSNMEEEHE SWDESDEELL AMEIRMRGQP RFANFRANTL SPVRFFVDKK WNTIPLRNKS 

       310        320        330        340        350        360 
LQRICAVDYD DSYDEILNGY EENSVVSYGQ GSIQSMVSSD STSPDSSLTE ESRSETASSL 

       370        380        390        400        410        420 
SQKICNGGLS PGNPGDSKDM KEIEPNYESP SSNNQDKDSS QASKSSIKVP ETHKAVLALR 

       430        440        450        460        470        480 
LEEKDGKIAV QTEKEESKAS TDVAGQAVTI NLVPTEEQAK PYRVVNLEQP LCKPYTVVDV 

       490        500        510        520        530        540 
SAAMASEHLE GPVNSPKTKS SSSTPNSPVT SSSLTPGQIS AHFQKSSAIR YQEVWTSSTS 

       550        560        570        580        590        600 
PRQKIPKVEL ITSGTGPNVP PRKNCHKSAP TSPTATNISS KTIPVKSPNL SEIKFNSYNN 

       610        620        630        640        650        660 
AGMPPFPIII HDEPTYARSS KNAIKVPIVI NPNAYDNLAI YKSFLGTSGE LSVKEKTTSV 

       670        680        690        700        710        720 
ISHTYEEIET ESKVPDNTTS KTTDCLQTKG FSNSTEHKRG SVAQKVQEFN NCLNRGQSSP 

       730        740        750        760        770        780 
QRSYSSSHSS PAKIQRATQE PVAKIEGTQE SQMVGSSSTR EKASTVLSQI VASIQPPQSP 

       790        800        810        820        830        840 
PETPQSGPKA CSVEELYAIP PDADVAKSTP KSTPVRPKSL FTSQPSGEAE APQTTDSPTT 

       850        860        870        880        890        900 
KVQKDPSIKP VTPSPSKLVT SPQSEPPAPF PPPRSTSSPY HAGNLLQRHF TNWTKPTSPT 

       910        920        930        940        950        960 
RSTEAESVLH SEGSRRAADA KPKRWISFKS FFRRRKTDEE DDKEKEREKG KLVGLDGTVI 

       970        980        990       1000       1010       1020 
HMLPPPPVQR HHWFTEAKGE SSEKPAIVFM YRCDPAQGQL SVDQSKARTD QAAVMEKGRA 

      1030       1040       1050       1060       1070       1080 
ENALLQDSEK KRSHSSPSQI PKKILSHMTH EVTEDFSPRD PRTVVGKQDG RGCTSVTTAL 

      1090       1100       1110       1120       1130       1140 
SLPELEREDG KEDISDPMDP NPCSATYSNL GQSRAAMIPP KQPRQPKGAV DDAIAFGGKT 

      1150       1160       1170       1180       1190       1200 
DQEAPNASQP TPPPLPKKMI IRANTEPISK DLQKSMESSL CVMANPTYDI DPNWDASSAG 

      1210       1220       1230       1240       1250       1260 
SSISYELKGL DIESYDSLER PLRKERPVPS AANSISSLTT LSIKDRFSNS MESLSSRRGP 

      1270       1280       1290       1300       1310       1320 
SCRQGRGIQK PQRQALYRGL ENREEVVGKI RSLHTDALKK LAVKCEDLFM AGQKDQLRFG 

      1330       1340       1350       1360       1370       1380 
VDSWSDFRLT SDKPCCEAGD AVYYTASYAK DPLNNYAVKI CKSKAKESQQ YYHSLAVRQS 

      1390       1400       1410       1420       1430       1440 
LAVHFNIQQD CGHFLAEVPN RLLPWEDPDD PEKDEDDMEE TEEDAKGETD GKNPKPCSEA 

      1450       1460       1470       1480       1490       1500 
ASSQKENQGV MSKKQRSHVV VITREVPCLT VADFVRDSLA QHGKSPDLYE RQVCLLLLQL 

      1510       1520       1530       1540       1550       1560 
CSGLEHLKPY HVTHCDLRLE NLLLVHYQPG GTAQGFGPAE PSPTSSYPTR LIVSNFSQAK 

      1570       1580       1590       1600       1610       1620 
QKSHLVDPEI LRDQSRLAPE IITATQYKKC DEFQTGILIY EMLHLPNPFD ENPELKEREY 

      1630       1640       1650       1660       1670       1680 
TRADLPRIPF RSPYSRGLQQ LASCLLNPNP SERILISDAK GILQCLLWGP REDLFQTFTA 

      1690       1700       1710       1720       1730       1740 
CPSLVQRNTL LQNWLDIKRT LLMIKFAEKS LDREGGISLE DWLCAQYLAF ATTDSLSCIV 


KILQHR 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the DNA sequence and duplication history of human chromosome 15."
Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. expand/collapse author list , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 537-1746.
Tissue: Lung, Mesangial cell and Smooth muscle.
[3]"The nucleotide sequence of a long cDNA clone isolated from human spleen."
Jikuya H., Takano J., Nomura N., Kikuno R., Nagase T., Ohara O.
Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 707-1120.
Tissue: Spleen.
[4]"Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method."
Ohara O., Nagase T., Mitsui G., Kohga H., Kikuno R., Hiraoka S., Takahashi Y., Kitajima S., Saga Y., Koseki H.
DNA Res. 9:47-57(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 983-1746.
Tissue: Brain.
[5]"The protein kinase complement of the human genome."
Manning G., Whyte D.B., Martinez R., Hunter T., Sudarsanam S.
Science 298:1912-1934(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.
[6]"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[7]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-540 AND SER-587, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[8]"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[9]"Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression."
Wang Y., Kelber J.A., Tran Cao H.S., Cantin G.T., Lin R., Wang W., Kaushal S., Bristow J.M., Edgington T.S., Hoffman R.M., Bouvet M., Yates J.R. III, Klemke R.L.
Proc. Natl. Acad. Sci. U.S.A. 107:10920-10925(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, CATALYTIC ACTIVITY, INTERACTION WITH BCAR1 AND CRK, SUBCELLULAR LOCATION, AUTOPHOSPHORYLATION, PHOSPHORYLATION BY CSK.
[10]Erratum
Wang Y., Kelber J.A., Tran Cao H.S., Cantin G.T., Lin R., Wang W., Kaushal S., Bristow J.M., Edgington T.S., Hoffman R.M., Bouvet M., Yates J.R. III, Klemke R.L.
Proc. Natl. Acad. Sci. U.S.A. 107:13556-13556(2010)
[11]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-281 AND TYR-635, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[12]"Patterns of somatic mutation in human cancer genomes."
Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A., Stevens C., Edkins S., O'Meara S., Vastrik I., Schmidt E.E., Avis T., Barthorpe S., Bhamra G., Buck G. expand/collapse author list , Choudhury B., Clements J., Cole J., Dicks E., Forbes S., Gray K., Halliday K., Harrison R., Hills K., Hinton J., Jenkinson A., Jones D., Menzies A., Mironenko T., Perry J., Raine K., Richardson D., Shepherd R., Small A., Tofts C., Varian J., Webb T., West S., Widaa S., Yates A., Cahill D.P., Louis D.N., Goldstraw P., Nicholson A.G., Brasseur F., Looijenga L., Weber B.L., Chiew Y.-E., DeFazio A., Greaves M.F., Green A.R., Campbell P., Birney E., Easton D.F., Chenevix-Trench G., Tan M.-H., Khoo S.K., Teh B.T., Yuen S.T., Leung S.Y., Wooster R., Futreal P.A., Stratton M.R.
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: VARIANTS [LARGE SCALE ANALYSIS] ARG-213; ILE-240; PRO-440; GLN-611; ILE-792; GLU-836; PHE-1035; LYS-1071; PRO-1077; LEU-1145; GLN-1408; THR-1542 AND GLY-1699.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC087465 Genomic DNA. No translation available.
AC107883 Genomic DNA. No translation available.
AK024793 mRNA. Translation: BAB15006.1. Different initiation.
AK091802 mRNA. No translation available.
AK127658 mRNA. Translation: BAC87076.1. Different initiation.
AK074157 mRNA. Translation: BAB84983.1.
AB082533 mRNA. Translation: BAC02711.1.
CCDSCCDS42062.1.
RefSeqNP_079052.2. NM_024776.3.
XP_005254727.1. XM_005254670.1.
XP_005254728.1. XM_005254671.1.
XP_005254729.1. XM_005254672.1.
XP_005254730.1. XM_005254673.1.
XP_005254731.1. XM_005254674.1.
XP_005254732.1. XM_005254675.2.
XP_006720754.1. XM_006720691.1.
UniGeneHs.731402.
Hs.9587.

3D structure databases

ProteinModelPortalQ9H792.
SMRQ9H792. Positions 1490-1658.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122926. 3 interactions.
DIPDIP-56276N.
IntActQ9H792. 5 interactions.
STRING9606.ENSP00000309230.

PTM databases

PhosphoSiteQ9H792.

Polymorphism databases

DMDM223634730.

Proteomic databases

MaxQBQ9H792.
PaxDbQ9H792.
PRIDEQ9H792.

Protocols and materials databases

DNASU79834.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000312493; ENSP00000309230; ENSG00000173517.
ENST00000560626; ENSP00000452796; ENSG00000173517.
GeneID79834.
KEGGhsa:79834.
UCSCuc002bcn.2. human.

Organism-specific databases

CTD79834.
GeneCardsGC15M077401.
H-InvDBHIX0012463.
HGNCHGNC:29431. PEAK1.
HPAHPA026313.
HPA026517.
MIM614248. gene.
neXtProtNX_Q9H792.
HUGESearch...
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG115841.
HOVERGENHBG093946.
InParanoidQ9H792.
KOK17538.
OMAGRFCYPE.
PhylomeDBQ9H792.

Enzyme and pathway databases

SignaLinkQ9H792.

Gene expression databases

ArrayExpressQ9H792.
BgeeQ9H792.
GenevestigatorQ9H792.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 2 hits.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSPEAK1. human.
GenomeRNAi79834.
NextBio69485.
PROQ9H792.
SOURCESearch...

Entry information

Entry namePEAK1_HUMAN
AccessionPrimary (citable) accession number: Q9H792
Secondary accession number(s): Q6ZS78 expand/collapse secondary AC list , Q8NAZ4, Q8NCM3, Q8TEG7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: February 10, 2009
Last modified: July 9, 2014
This is version 108 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human and mouse protein kinases

Human and mouse protein kinases: classification and index

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 15

Human chromosome 15: entries, gene names and cross-references to MIM