##gff-version 3 Q9H6U6 UniProtKB Chain 1 928 . . . ID=PRO_0000050883;Note=BCAS3 microtubule associated cell migration factor Q9H6U6 UniProtKB Repeat 69 114 . . . Note=WD;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9H6U6 UniProtKB Region 254 312 . . . Note=Required for recruitment to preautophagosomal structure in response to mitophagy;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Region 437 560 . . . Note=Required for recruitment to preautophagosomal structure in response to mitophagy;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Region 472 515 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9H6U6 UniProtKB Region 755 777 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9H6U6 UniProtKB Region 868 928 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9H6U6 UniProtKB Compositional bias 473 515 . . . Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9H6U6 UniProtKB Compositional bias 755 773 . . . Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9H6U6 UniProtKB Compositional bias 882 928 . . . Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9H6U6 UniProtKB Site 824 825 . . . Note=Breakpoint for translocation to form BCAS4-BCAS3 Q9H6U6 UniProtKB Modified residue 1 1 . . . Note=N-acetylmethionine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:22814378;Dbxref=PMID:22814378 Q9H6U6 UniProtKB Modified residue 461 461 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8CCN5 Q9H6U6 UniProtKB Modified residue 480 480 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:18669648;Dbxref=PMID:18669648 Q9H6U6 UniProtKB Modified residue 488 488 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8CCN5 Q9H6U6 UniProtKB Modified residue 838 838 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8CCN5 Q9H6U6 UniProtKB Modified residue 886 886 . . . Note=Phosphoserine;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:19690332,ECO:0007744|PubMed:23186163;Dbxref=PMID:19690332,PMID:23186163 Q9H6U6 UniProtKB Modified residue 898 898 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8CCN5 Q9H6U6 UniProtKB Cross-link 215 215 . . . Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)%3B alternate;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:25114211;Dbxref=PMID:25114211 Q9H6U6 UniProtKB Cross-link 215 215 . . . Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)%3B alternate;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:25114211,ECO:0007744|PubMed:28112733;Dbxref=PMID:25114211,PMID:28112733 Q9H6U6 UniProtKB Alternative sequence 1 229 . . . ID=VSP_040112;Note=In isoform 6. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|Ref.6;Dbxref=PMID:14702039 Q9H6U6 UniProtKB Alternative sequence 547 561 . . . ID=VSP_007858;Note=In isoform 1%2C isoform 3%2C isoform 5 and isoform 6. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:12378525,ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|Ref.6;Dbxref=PMID:12378525,PMID:14702039,PMID:15489334 Q9H6U6 UniProtKB Alternative sequence 879 879 . . . ID=VSP_007860;Note=In isoform 3 and isoform 4. T->TDTALDVAVKTFPPERHVAVKCF;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:17974005;Dbxref=PMID:14702039,PMID:17974005 Q9H6U6 UniProtKB Alternative sequence 880 928 . . . ID=VSP_040113;Note=In isoform 5. ELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNESQPLSLFPTGFP->DTALDVAVKTFPPERHVAVKCFGKKKGKKKQCQQPSVREQPNSNKACVRDGGRTSARGKHRDSE;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 Q9H6U6 UniProtKB Natural variant 25 928 . . . ID=VAR_086504;Note=In HEMARS. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34022130;Dbxref=PMID:34022130 Q9H6U6 UniProtKB Natural variant 87 87 . . . ID=VAR_065093;Note=N->S;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12378525,ECO:0000269|PubMed:14702039,ECO:0000269|PubMed:15489334,ECO:0000269|Ref.4;Dbxref=dbSNP:rs2643103,PMID:12378525,PMID:14702039,PMID:15489334 Q9H6U6 UniProtKB Natural variant 106 106 . . . ID=VAR_057583;Note=I->V;Dbxref=dbSNP:rs34712615 Q9H6U6 UniProtKB Natural variant 113 928 . . . ID=VAR_086505;Note=In HEMARS. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34022130;Dbxref=PMID:34022130 Q9H6U6 UniProtKB Natural variant 192 928 . . . ID=VAR_086506;Note=In HEMARS. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34022130;Dbxref=PMID:34022130 Q9H6U6 UniProtKB Natural variant 242 928 . . . ID=VAR_086507;Note=In HEMARS. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34022130;Dbxref=PMID:34022130 Q9H6U6 UniProtKB Natural variant 486 928 . . . ID=VAR_086508;Note=In HEMARS. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34022130;Dbxref=PMID:34022130 Q9H6U6 UniProtKB Natural variant 567 567 . . . ID=VAR_086509;Note=In HEMARS%3B no protein detected in patient cells that also carry R-577%2C suggesting the mutant is unstable. P->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34022130;Dbxref=dbSNP:rs754857276,PMID:34022130 Q9H6U6 UniProtKB Natural variant 577 577 . . . ID=VAR_086510;Note=In HEMARS%3B no protein detected in patient cells that also carry L-567%2C suggesting the mutant is unstable. G->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34022130;Dbxref=dbSNP:rs772813265,PMID:34022130 Q9H6U6 UniProtKB Natural variant 743 928 . . . ID=VAR_086511;Note=In HEMARS. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34022130;Dbxref=PMID:34022130 Q9H6U6 UniProtKB Mutagenesis 350 350 . . . Note=No effect on recruitment to preautophagosomal structure in response to mitophagy. No effect on interaction with PHAF1. H->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Mutagenesis 370 370 . . . Note=Decreases recruitment to preautophagosomal structure in response to mitophagy. No effect on interaction with PHAF1. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Mutagenesis 372 372 . . . Note=No effect on recruitment to preautophagosomal structure in response to mitophagy. No effect on interaction with PHAF1. L->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Mutagenesis 377 377 . . . Note=No effect on recruitment to preautophagosomal structure in response to mitophagy. No effect on interaction with PHAF1. H->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Mutagenesis 400 400 . . . Note=Decreases recruitment to preautophagosomal structure in response to mitophagy. No effect on interaction with PHAF1. H->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Mutagenesis 401 401 . . . Note=Almost abolishes recruitment to preautophagosomal structure in response to mitophagy. No effect on interaction with PHAF1. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Mutagenesis 426 426 . . . Note=Decreases recruitment to preautophagosomal structure in response to mitophagy. No effect on interaction with PHAF1. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Mutagenesis 428 428 . . . Note=Almost abolishes recruitment to preautophagosomal structure in response to mitophagy. No effect on interaction with PHAF1. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Mutagenesis 430 430 . . . Note=Almost abolishes recruitment to preautophagosomal structure in response to mitophagy. No effect on interaction with PHAF1. H->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33499712;Dbxref=PMID:33499712 Q9H6U6 UniProtKB Sequence conflict 29 29 . . . Note=E->K;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9H6U6 UniProtKB Sequence conflict 127 127 . . . Note=R->K;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9H6U6 UniProtKB Sequence conflict 199 200 . . . Note=VV->II;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9H6U6 UniProtKB Sequence conflict 533 533 . . . Note=K->E;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9H6U6 UniProtKB Sequence conflict 640 640 . . . Note=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9H6U6 UniProtKB Sequence conflict 666 666 . . . Note=Q->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9H6U6 UniProtKB Sequence conflict 806 806 . . . Note=S->P;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9H6U6 UniProtKB Sequence conflict 891 891 . . . Note=G->R;Ontology_term=ECO:0000305;evidence=ECO:0000305