Reviewed, UniProtKB/Swiss-Prot Q9H6U6 (BCAS3_HUMAN)

Names and origin

Protein names

Recommended name:
    Breast carcinoma-amplified sequence 3
Alternative name(s):
    Maab1 protein
    GAOB1

Gene names

Name:

BCAS3

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	928 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Nucleus Potential.
Tissue specificity	Stomach, liver, lung, kidney, prostate, testis, thyroid gland, adrenal gland, brain, heart, skeletal muscle, colon, spleen, small intestine, placenta, blood leucocyte and mammary epithelial cells. Overexpressed in most breast cancer cell lines. Ref.1
Developmental stage	Fetal.
Involvement in disease	A chromosomal aberration involving BCAS3 may be a cause of breast cancer. Translocation t(17;20)(q23;q13) with BCAS4.
Sequence similarities	Belongs to the WD repeat BCAS3 family. Contains 3 WD repeats.
Sequence caution	The sequence AAF70324.1 differs from that shown. Reason: Frameshift at position 693.

Ontologies

Keywords
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing Chromosomal rearrangement Polymorphism
Disease	Proto-oncogene
Domain	Repeat WD repeat
PTM	Phosphoprotein
Gene Ontology (GO)
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 2 (identifier: Q9H6U6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 1 (identifier: Q9H6U6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     547-561: Missing.

Isoform 3 (identifier: Q9H6U6-3)

The sequence of this isoform differs from the canonical sequence as follows:
     547-561: Missing.
     879-879: T → TDTALDVAVKTFPPERHVAVKCF

Isoform 4 (identifier: Q9H6U6-4)

The sequence of this isoform differs from the canonical sequence as follows:
     546-546: G → GPYLFGAGCFSIKAPC
     879-879: T → TDTALDVAVKTFPPERHVAVKCF

Isoform 5 (identifier: Q9H6U6-5)

The sequence of this isoform differs from the canonical sequence as follows:
     1-829: Missing.
     830-879: VTLLEVCGSW...PSRDVVGSGT → ALDVAVKTFP...VTKHAFGMEE

Note: Incomplete sequence. No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 928	928	Breast carcinoma-amplified sequence 3		PRO_0000050883
Regions
	Repeat	69 – 114	46	WD 1
	Repeat	349 – 389	41	WD 2
	Repeat	403 – 447	45	WD 3
Sites
	Site	824 – 825	2	Breakpoint for translocation to form BCAS4-BCAS3
Amino acid modifications
	Modified residue	480	1	Phosphoserine Ref.7
	Modified residue	488	1	Phosphoserine Ref.7
	Modified residue	869	1	Phosphoserine By similarity
	Modified residue	886	1	Phosphoserine By similarity
Natural variations
	Alternative sequence	1 – 829	829	Missing in isoform 5.		VSP_007856
	Alternative sequence	546	1	G → GPYLFGAGCFSIKAPC in isoform 4.		VSP_007857
	Alternative sequence	547 – 561	15	Missing in isoform 1 and isoform 3.		VSP_007858
	Alternative sequence	830 – 879	50	VTLLE…VGSGT → ALDVAVKTFPPERHVAVKCF GKKKGKKNNANSPASVSNPT VTKHAFGMEE in isoform 5.		VSP_007859
	Alternative sequence	879	1	T → TDTALDVAVKTFPPERHVAV KCF in isoform 3 and isoform 4.		VSP_007860
	Natural variant	106	1	I → V: dbSNP rs34712615.		VAR_057583
Experimental info
	Sequence conflict	29	1	K → E in BAB15156. Ref.2
	Sequence conflict	127	1	K → R in BAB15156. Ref.2
	Sequence conflict	199 – 200	2	VV → II in BAB15156. Ref.2
	Sequence conflict	533	1	K → E in BAB14380. Ref.2
	Sequence conflict	640	1	D → G in BAB15156. Ref.2
	Sequence conflict	666	1	Q → R in BAB14078. Ref.2
	Sequence conflict	806	1	S → P in BAB15156. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 2 [UniParc]. Last modified July 25, 2003. Version 2. Checksum: F6CF90372C344765	FASTA	928	101,181
	10 20 30 40 50 60 MNEAMATDSP RRPSRCTGGV VVRPQAVTKQ SYMESVVTFL QDVVPQAYSG TPLTEEKEKI 70 80 90 100 110 120 VWVRFENADL NDTSRNLEFH EIHSTGSEPP LLIMIGYSDG MQVWSIPISG EAQELFSVRH 130 140 150 160 170 180 GPIRAAKILP APQFGAQKCD NFAEKRPLLG VCKSIGSSGT SPPYCCVDLY SLRTGEMVKS 190 200 210 220 230 240 IQFKTPIYDL HCNKRILVVV LQEKIAAFDS CTFTKKFFVT SCYPCPGPNM NPIALGSRWL 250 260 270 280 290 300 AYAENKLIRC HQSRGGACGD NIQSYTATVI SAAKTLKSGL TMVGKVVTQL TGTLPSGVTE 310 320 330 340 350 360 DDVAIHSNSR RSPLVPGIIT VIDTETVGEG QVLVSEDSDS DGIVAHFPAH EKPVCCMAFN 370 380 390 400 410 420 TSGMLLVTTD TLGHDFHVFQ ILTHPWSSSQ CAVHHLYTLH RGETEAKVQD ICFSHDCRWV 430 440 450 460 470 480 VVSTLRGTSH VFPINPYGGQ PCVRTHMSPR VVNRMSRFQK SAGLEEIEQE LTSKQGGRCS 490 500 510 520 530 540 PVPGLSSSPS GSPLHGKLNS QDSYNNFTNN NPGNPRLSPL PSLMVVMPLA QIKQPMTLGT 550 560 570 580 590 600 ITKRTGPYLF GAGCFSIKAP CKVKPPPQIS PSKSMGGEFC VAAIFGTSRS WFANNAGLKR 610 620 630 640 650 660 EKDQSKQVVV ESLYIISCYG TLVEHMMEPR PLSTAPKISD DTPLEMMTSP RASWTLVRTP 670 680 690 700 710 720 QWNELQPPFN ANHPLLLAAD AVQYYQFLLA GLVPPGSPGP ITRHGSYDSL ASDHSGQEDE 730 740 750 760 770 780 EWLSQVEIVT HTGPHRRLWM GPQFQFKTIH PSGQTTVISS SSSVLQSHGP SDTPQPLLDF 790 800 810 820 830 840 DTDDLDLNSL RIQPVRSDPV SMPGSSRPVS DRRGVSTVID AASGTFDRSV TLLEVCGSWP 850 860 870 880 890 900 EGFGLRHMSS MEHTEEGLRE RLADAMAESP SRDVVGSGTE LQREGSIETL SNSSGSTSGS 910 920 IPRNFDGYRS PLPTNESQPL SLFPTGFP
	Isoform 1. Checksum: 836663A9AB1C8170	FASTA	913	99,625
	10 20 30 40 50 60 MNEAMATDSP RRPSRCTGGV VVRPQAVTKQ SYMESVVTFL QDVVPQAYSG TPLTEEKEKI 70 80 90 100 110 120 VWVRFENADL NDTSRNLEFH EIHSTGSEPP LLIMIGYSDG MQVWSIPISG EAQELFSVRH 130 140 150 160 170 180 GPIRAAKILP APQFGAQKCD NFAEKRPLLG VCKSIGSSGT SPPYCCVDLY SLRTGEMVKS 190 200 210 220 230 240 IQFKTPIYDL HCNKRILVVV LQEKIAAFDS CTFTKKFFVT SCYPCPGPNM NPIALGSRWL 250 260 270 280 290 300 AYAENKLIRC HQSRGGACGD NIQSYTATVI SAAKTLKSGL TMVGKVVTQL TGTLPSGVTE 310 320 330 340 350 360 DDVAIHSNSR RSPLVPGIIT VIDTETVGEG QVLVSEDSDS DGIVAHFPAH EKPVCCMAFN 370 380 390 400 410 420 TSGMLLVTTD TLGHDFHVFQ ILTHPWSSSQ CAVHHLYTLH RGETEAKVQD ICFSHDCRWV 430 440 450 460 470 480 VVSTLRGTSH VFPINPYGGQ PCVRTHMSPR VVNRMSRFQK SAGLEEIEQE LTSKQGGRCS 490 500 510 520 530 540 PVPGLSSSPS GSPLHGKLNS QDSYNNFTNN NPGNPRLSPL PSLMVVMPLA QIKQPMTLGT 550 560 570 580 590 600 ITKRTGKVKP PPQISPSKSM GGEFCVAAIF GTSRSWFANN AGLKREKDQS KQVVVESLYI 610 620 630 640 650 660 ISCYGTLVEH MMEPRPLSTA PKISDDTPLE MMTSPRASWT LVRTPQWNEL QPPFNANHPL 670 680 690 700 710 720 LLAADAVQYY QFLLAGLVPP GSPGPITRHG SYDSLASDHS GQEDEEWLSQ VEIVTHTGPH 730 740 750 760 770 780 RRLWMGPQFQ FKTIHPSGQT TVISSSSSVL QSHGPSDTPQ PLLDFDTDDL DLNSLRIQPV 790 800 810 820 830 840 RSDPVSMPGS SRPVSDRRGV STVIDAASGT FDRSVTLLEV CGSWPEGFGL RHMSSMEHTE 850 860 870 880 890 900 EGLRERLADA MAESPSRDVV GSGTELQREG SIETLSNSSG STSGSIPRNF DGYRSPLPTN 910 ESQPLSLFPT GFP
	Isoform 3. Checksum: DAEC1A4092E62C3D	FASTA	935	102,051
	10 20 30 40 50 60 MNEAMATDSP RRPSRCTGGV VVRPQAVTKQ SYMESVVTFL QDVVPQAYSG TPLTEEKEKI 70 80 90 100 110 120 VWVRFENADL NDTSRNLEFH EIHSTGSEPP LLIMIGYSDG MQVWSIPISG EAQELFSVRH 130 140 150 160 170 180 GPIRAAKILP APQFGAQKCD NFAEKRPLLG VCKSIGSSGT SPPYCCVDLY SLRTGEMVKS 190 200 210 220 230 240 IQFKTPIYDL HCNKRILVVV LQEKIAAFDS CTFTKKFFVT SCYPCPGPNM NPIALGSRWL 250 260 270 280 290 300 AYAENKLIRC HQSRGGACGD NIQSYTATVI SAAKTLKSGL TMVGKVVTQL TGTLPSGVTE 310 320 330 340 350 360 DDVAIHSNSR RSPLVPGIIT VIDTETVGEG QVLVSEDSDS DGIVAHFPAH EKPVCCMAFN 370 380 390 400 410 420 TSGMLLVTTD TLGHDFHVFQ ILTHPWSSSQ CAVHHLYTLH RGETEAKVQD ICFSHDCRWV 430 440 450 460 470 480 VVSTLRGTSH VFPINPYGGQ PCVRTHMSPR VVNRMSRFQK SAGLEEIEQE LTSKQGGRCS 490 500 510 520 530 540 PVPGLSSSPS GSPLHGKLNS QDSYNNFTNN NPGNPRLSPL PSLMVVMPLA QIKQPMTLGT 550 560 570 580 590 600 ITKRTGKVKP PPQISPSKSM GGEFCVAAIF GTSRSWFANN AGLKREKDQS KQVVVESLYI 610 620 630 640 650 660 ISCYGTLVEH MMEPRPLSTA PKISDDTPLE MMTSPRASWT LVRTPQWNEL QPPFNANHPL 670 680 690 700 710 720 LLAADAVQYY QFLLAGLVPP GSPGPITRHG SYDSLASDHS GQEDEEWLSQ VEIVTHTGPH 730 740 750 760 770 780 RRLWMGPQFQ FKTIHPSGQT TVISSSSSVL QSHGPSDTPQ PLLDFDTDDL DLNSLRIQPV 790 800 810 820 830 840 RSDPVSMPGS SRPVSDRRGV STVIDAASGT FDRSVTLLEV CGSWPEGFGL RHMSSMEHTE 850 860 870 880 890 900 EGLRERLADA MAESPSRDVV GSGTDTALDV AVKTFPPERH VAVKCFELQR EGSIETLSNS 910 920 930 SGSTSGSIPR NFDGYRSPLP TNESQPLSLF PTGFP
	Isoform 4. Checksum: C16F20D1D72DEBDE	FASTA	965	105,162
	10 20 30 40 50 60 MNEAMATDSP RRPSRCTGGV VVRPQAVTKQ SYMESVVTFL QDVVPQAYSG TPLTEEKEKI 70 80 90 100 110 120 VWVRFENADL NDTSRNLEFH EIHSTGSEPP LLIMIGYSDG MQVWSIPISG EAQELFSVRH 130 140 150 160 170 180 GPIRAAKILP APQFGAQKCD NFAEKRPLLG VCKSIGSSGT SPPYCCVDLY SLRTGEMVKS 190 200 210 220 230 240 IQFKTPIYDL HCNKRILVVV LQEKIAAFDS CTFTKKFFVT SCYPCPGPNM NPIALGSRWL 250 260 270 280 290 300 AYAENKLIRC HQSRGGACGD NIQSYTATVI SAAKTLKSGL TMVGKVVTQL TGTLPSGVTE 310 320 330 340 350 360 DDVAIHSNSR RSPLVPGIIT VIDTETVGEG QVLVSEDSDS DGIVAHFPAH EKPVCCMAFN 370 380 390 400 410 420 TSGMLLVTTD TLGHDFHVFQ ILTHPWSSSQ CAVHHLYTLH RGETEAKVQD ICFSHDCRWV 430 440 450 460 470 480 VVSTLRGTSH VFPINPYGGQ PCVRTHMSPR VVNRMSRFQK SAGLEEIEQE LTSKQGGRCS 490 500 510 520 530 540 PVPGLSSSPS GSPLHGKLNS QDSYNNFTNN NPGNPRLSPL PSLMVVMPLA QIKQPMTLGT 550 560 570 580 590 600 ITKRTGPYLF GAGCFSIKAP CPYLFGAGCF SIKAPCKVKP PPQISPSKSM GGEFCVAAIF 610 620 630 640 650 660 GTSRSWFANN AGLKREKDQS KQVVVESLYI ISCYGTLVEH MMEPRPLSTA PKISDDTPLE 670 680 690 700 710 720 MMTSPRASWT LVRTPQWNEL QPPFNANHPL LLAADAVQYY QFLLAGLVPP GSPGPITRHG 730 740 750 760 770 780 SYDSLASDHS GQEDEEWLSQ VEIVTHTGPH RRLWMGPQFQ FKTIHPSGQT TVISSSSSVL 790 800 810 820 830 840 QSHGPSDTPQ PLLDFDTDDL DLNSLRIQPV RSDPVSMPGS SRPVSDRRGV STVIDAASGT 850 860 870 880 890 900 FDRSVTLLEV CGSWPEGFGL RHMSSMEHTE EGLRERLADA MAESPSRDVV GSGTDTALDV 910 920 930 940 950 960 AVKTFPPERH VAVKCFELQR EGSIETLSNS SGSTSGSIPR NFDGYRSPLP TNESQPLSLF PTGFP
	Isoform 5. Checksum: 52724E335977A709	FASTA	99	10,606
	10 20 30 40 50 60 ALDVAVKTFP PERHVAVKCF GKKKGKKNNA NSPASVSNPT VTKHAFGMEE ELQREGSIET 70 80 90 LSNSSGSTSG SIPRNFDGYR SPLPTNESQP LSLFPTGFP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning of BCAS3 (17q23) and BCAS4 (20q13) genes that undergo amplification, overexpression, and fusion in breast cancer." Baerlund M., Monni O., Weaver J.D., Kauraniemi P., Sauter G., Heiskanen M., Kallioniemi O.-P., Kallioniemi A. Genes Chromosomes Cancer 35:311-317(2002) [PubMed: 12378525] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, CHROMOSOMAL TRANSLOCATION WITH BCAS4. Tissue: Liver.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3). Tissue: Colon.
[3]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Blocker H., Heubner D., Hoerlein A., Michel G., Wedler H., Kohrer K., Ottenwalder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 475-928 (ISOFORM 4). Tissue: Brain.
[4]	"Five novel genes from 17q23 amplicon have different amplification and overexpression frequency in breast cancer." Wu G., Couch F.J. Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 510-928 (ISOFORM 1).
[5]	"Cloning and sequencing of a new isoform similar to FLJ20128." Bauer M. Thesis (2002), University of Leipzig, Germany Cited for: PARTIAL NUCLEOTIDE SEQUENCE (ISOFORM 5).
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 469-928 (ISOFORM 1). Tissue: Cervix.
[7]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed: 18669648] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-480 AND SER-488, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Web resources

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF361219 mRNA. Translation: AAL99632.1. AF361221 mRNA. Translation: AAL99634.1. Different initiation. AK000135 mRNA. Translation: BAA90966.1. Different initiation. AK022526 mRNA. Translation: BAB14078.1. Sequence problems. AK023054 mRNA. Translation: BAB14380.1. Different initiation. AK025510 mRNA. Translation: BAB15156.1. AL831895 mRNA. Translation: CAD38568.1. AF260268 mRNA. Translation: AAF70324.1. Frameshift. AJ511332 mRNA. Translation: CAD54076.1. BC001250 mRNA. Translation: AAH01250.1. Different initiation.
IPI	IPI00332095. IPI00332097. IPI00332098. IPI00411606. IPI00783452.
UniGene	Hs.655028
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	Q9H6U6.
Proteomic databases
PRIDE	Q9H6U6.
Genome annotation databases
Ensembl	ENSG00000141376. Homo sapiens. [Contig view]
Organism-specific databases
GeneCards	GC17P056109.
H-InvDB	HIX0021877.
HGNC	HGNC:14347. BCAS3.
MIM	607470. gene.
PharmGKB	PA25286.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q9H6U6.
Gene expression databases
Bgee	Q9H6U6.
GermOnline	ENSG00000141376. Homo sapiens.
Family and domain databases
InterPro	IPR001680. WD40_repeat. IPR019775. WD40_repeat_CS. [Graphical view]
SMART	SM00320. WD40. 2 hits. [Graphical view]
PROSITE	PS00678. WD_REPEATS_1. False negative. PS50082. WD_REPEATS_2. False negative. PS50294. WD_REPEATS_REGION. False negative. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

BCAS3_HUMAN

Accession

Primary (citable) accession number: Q9H6U6
Secondary accession number(s): Q8IXI6 , Q8NDR8, Q8TDL9, Q8TDM1, Q8WY55, Q9BVF0, Q9H957, Q9H9Y9, Q9NXP4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2003
Last sequence update:	July 25, 2003
Last modified:	June 16, 2009
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)