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Q9H6Q4

- NARFL_HUMAN

UniProt

Q9H6Q4 - NARFL_HUMAN

Protein

Cytosolic Fe-S cluster assembly factor NARFL

Gene

NARFL

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 104 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.2 Publications

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi24 – 241Iron-sulfur 1 (4Fe-4S)Sequence Analysis
    Metal bindingi71 – 711Iron-sulfur 1 (4Fe-4S)Sequence Analysis
    Metal bindingi74 – 741Iron-sulfur 1 (4Fe-4S)Sequence Analysis
    Metal bindingi77 – 771Iron-sulfur 1 (4Fe-4S)Sequence Analysis
    Metal bindingi190 – 1901Iron-sulfur 2 (4Fe-4S)Sequence Analysis
    Metal bindingi246 – 2461Iron-sulfur 2 (4Fe-4S)Sequence Analysis
    Metal bindingi395 – 3951Iron-sulfur 2 (4Fe-4S)Sequence Analysis
    Metal bindingi399 – 3991Iron-sulfur 2 (4Fe-4S)Sequence Analysis

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. iron-sulfur cluster assembly Source: UniProtKB
    2. oxygen homeostasis Source: HGNC
    3. regulation of transcription, DNA-templated Source: HGNC
    4. response to hypoxia Source: HGNC
    5. small molecule metabolic process Source: Reactome

    Keywords - Ligandi

    4Fe-4S, Iron, Iron-sulfur, Metal-binding

    Enzyme and pathway databases

    ReactomeiREACT_160176. Cytosolic iron-sulfur cluster assembly.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytosolic Fe-S cluster assembly factor NARFL
    Alternative name(s):
    Iron-only hydrogenase-like protein 1
    Short name:
    IOP1
    Nuclear prelamin A recognition factor-like protein
    Protein related to Narf
    Gene namesi
    Name:NARFL
    Synonyms:PRN
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 16

    Organism-specific databases

    HGNCiHGNC:14179. NARFL.

    Subcellular locationi

    GO - Cellular componenti

    1. CIA complex Source: UniProtKB

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA128394707.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 476475Cytosolic Fe-S cluster assembly factor NARFLPRO_0000288485Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanine1 Publication

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiQ9H6Q4.
    PaxDbiQ9H6Q4.
    PeptideAtlasiQ9H6Q4.
    PRIDEiQ9H6Q4.

    PTM databases

    PhosphoSiteiQ9H6Q4.

    Expressioni

    Tissue specificityi

    Widely expressed.1 Publication

    Gene expression databases

    ArrayExpressiQ9H6Q4.
    BgeeiQ9H6Q4.
    CleanExiHS_NARFL.
    GenevestigatoriQ9H6Q4.

    Organism-specific databases

    HPAiHPA040851.

    Interactioni

    Subunit structurei

    Component of the CIA complex.2 Publications

    Protein-protein interaction databases

    BioGridi122176. 4 interactions.
    STRINGi9606.ENSP00000251588.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9H6Q4.
    SMRiQ9H6Q4. Positions 70-464.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NARF family.Curated

    Phylogenomic databases

    eggNOGiCOG4624.
    HOGENOMiHOG000191744.
    HOVERGENiHBG055005.
    OMAiFIGPSQD.
    OrthoDBiEOG7VB2FK.
    PhylomeDBiQ9H6Q4.
    TreeFamiTF106273.

    Family and domain databases

    Gene3Di4.10.260.20. 1 hit.
    InterProiIPR009016. Fe_hydrogenase.
    IPR004108. Fe_hydrogenase_lsu_C.
    IPR003149. Fe_hydrogenase_ssu-like.
    [Graphical view]
    PfamiPF02906. Fe_hyd_lg_C. 1 hit.
    PF02256. Fe_hyd_SSU. 1 hit.
    [Graphical view]
    SMARTiSM00902. Fe_hyd_SSU. 1 hit.
    [Graphical view]
    SUPFAMiSSF53920. SSF53920. 2 hits.

    Sequences (3)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9H6Q4-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MASPFSGALQ LTDLDDFIGP SQECIKPVKV EKRAGSGVAK IRIEDDGSYF    50
    QINQDGGTRR LEKAKVSLND CLACSGCITS AETVLITQQS HEELKKVLDA 100
    NKMAAPSQQR LVVVSVSPQS RASLAARFQL NPTDTARKLT SFFKKIGVHF 150
    VFDTAFSRHF SLLESQREFV RRFRGQADCR QALPLLASAC PGWICYAEKT 200
    HGSFILPHIS TARSPQQVMG SLVKDFFAQQ QHLTPDKIYH VTVMPCYDKK 250
    LEASRPDFFN QEHQTRDVDC VLTTGEVFRL LEEEGVSLPD LEPAPLDSLC 300
    SGASAEEPTS HRGGGSGGYL EHVFRHAARE LFGIHVAEVT YKPLRNKDFQ 350
    EVTLEKEGQV LLHFAMAYGF RNIQNLVQRL KRGRCPYHYV EVMACPSGCL 400
    NGGGQLQAPD RPSRELLQHV ERLYGMVRAE APEDAPGVQE LYTHWLQGTD 450
    SECAGRLLHT QYHAVEKAST GLGIRW 476
    Length:476
    Mass (Da):53,020
    Last modified:March 1, 2001 - v1
    Checksum:i88A019DA4D7988EA
    GO
    Isoform 2 (identifier: Q9H6Q4-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-243: Missing.

    Show »
    Length:233
    Mass (Da):26,135
    Checksum:iAA85FD01731E7051
    GO
    Isoform 3 (identifier: Q9H6Q4-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-102: Missing.

    Show »
    Length:374
    Mass (Da):42,010
    Checksum:iD22B5E1FFD155545
    GO

    Sequence cautioni

    The sequence AAK61251.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti205 – 2051I → T in BAD96725. 1 PublicationCurated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti38 – 381V → M.
    Corresponds to variant rs8045850 [ dbSNP | Ensembl ].
    VAR_053911
    Natural varianti444 – 4441H → R.
    Corresponds to variant rs7188554 [ dbSNP | Ensembl ].
    VAR_053912

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 243243Missing in isoform 2. 1 PublicationVSP_025694Add
    BLAST
    Alternative sequencei1 – 102102Missing in isoform 3. 1 PublicationVSP_025695Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY129231 mRNA. Translation: AAM98737.1.
    AK025641 mRNA. Translation: BAB15199.1.
    AK025861 mRNA. Translation: BAB15261.1.
    AK095675 mRNA. Translation: BAG53105.1.
    AK223005 mRNA. Translation: BAD96725.1.
    AE006464 Genomic DNA. Translation: AAK61251.1. Sequence problems.
    Z98258 Genomic DNA. Translation: CAM26480.1.
    CH471112 Genomic DNA. Translation: EAW85723.1.
    BC030248 mRNA. Translation: AAH30248.1.
    BC129940 mRNA. Translation: AAI29941.1.
    CCDSiCCDS10425.1. [Q9H6Q4-1]
    RefSeqiNP_071938.1. NM_022493.1. [Q9H6Q4-1]
    XP_005255557.1. XM_005255500.1. [Q9H6Q4-3]
    UniGeneiHs.513247.

    Genome annotation databases

    EnsembliENST00000251588; ENSP00000251588; ENSG00000103245. [Q9H6Q4-1]
    ENST00000540986; ENSP00000444008; ENSG00000103245. [Q9H6Q4-3]
    ENST00000568545; ENSP00000457058; ENSG00000103245. [Q9H6Q4-3]
    GeneIDi64428.
    KEGGihsa:64428.
    UCSCiuc002cjp.3. human. [Q9H6Q4-1]

    Polymorphism databases

    DMDMi74733617.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY129231 mRNA. Translation: AAM98737.1 .
    AK025641 mRNA. Translation: BAB15199.1 .
    AK025861 mRNA. Translation: BAB15261.1 .
    AK095675 mRNA. Translation: BAG53105.1 .
    AK223005 mRNA. Translation: BAD96725.1 .
    AE006464 Genomic DNA. Translation: AAK61251.1 . Sequence problems.
    Z98258 Genomic DNA. Translation: CAM26480.1 .
    CH471112 Genomic DNA. Translation: EAW85723.1 .
    BC030248 mRNA. Translation: AAH30248.1 .
    BC129940 mRNA. Translation: AAI29941.1 .
    CCDSi CCDS10425.1. [Q9H6Q4-1 ]
    RefSeqi NP_071938.1. NM_022493.1. [Q9H6Q4-1 ]
    XP_005255557.1. XM_005255500.1. [Q9H6Q4-3 ]
    UniGenei Hs.513247.

    3D structure databases

    ProteinModelPortali Q9H6Q4.
    SMRi Q9H6Q4. Positions 70-464.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 122176. 4 interactions.
    STRINGi 9606.ENSP00000251588.

    PTM databases

    PhosphoSitei Q9H6Q4.

    Polymorphism databases

    DMDMi 74733617.

    Proteomic databases

    MaxQBi Q9H6Q4.
    PaxDbi Q9H6Q4.
    PeptideAtlasi Q9H6Q4.
    PRIDEi Q9H6Q4.

    Protocols and materials databases

    DNASUi 64428.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000251588 ; ENSP00000251588 ; ENSG00000103245 . [Q9H6Q4-1 ]
    ENST00000540986 ; ENSP00000444008 ; ENSG00000103245 . [Q9H6Q4-3 ]
    ENST00000568545 ; ENSP00000457058 ; ENSG00000103245 . [Q9H6Q4-3 ]
    GeneIDi 64428.
    KEGGi hsa:64428.
    UCSCi uc002cjp.3. human. [Q9H6Q4-1 ]

    Organism-specific databases

    CTDi 64428.
    GeneCardsi GC16M000794.
    HGNCi HGNC:14179. NARFL.
    HPAi HPA040851.
    MIMi 611118. gene.
    neXtProti NX_Q9H6Q4.
    PharmGKBi PA128394707.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG4624.
    HOGENOMi HOG000191744.
    HOVERGENi HBG055005.
    OMAi FIGPSQD.
    OrthoDBi EOG7VB2FK.
    PhylomeDBi Q9H6Q4.
    TreeFami TF106273.

    Enzyme and pathway databases

    Reactomei REACT_160176. Cytosolic iron-sulfur cluster assembly.

    Miscellaneous databases

    GenomeRNAii 64428.
    NextBioi 66437.
    PROi Q9H6Q4.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9H6Q4.
    Bgeei Q9H6Q4.
    CleanExi HS_NARFL.
    Genevestigatori Q9H6Q4.

    Family and domain databases

    Gene3Di 4.10.260.20. 1 hit.
    InterProi IPR009016. Fe_hydrogenase.
    IPR004108. Fe_hydrogenase_lsu_C.
    IPR003149. Fe_hydrogenase_ssu-like.
    [Graphical view ]
    Pfami PF02906. Fe_hyd_lg_C. 1 hit.
    PF02256. Fe_hyd_SSU. 1 hit.
    [Graphical view ]
    SMARTi SM00902. Fe_hyd_SSU. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53920. SSF53920. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "A comparison of Narf, HPRN and Nar1p in human and yeast cells."
      Barton R.M., Worman H.J.
      Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3).
      Tissue: Brain.
    3. Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Small intestine.
    4. "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."
      Daniels R.J., Peden J.F., Lloyd C., Horsley S.W., Clark K., Tufarelli C., Kearney L., Buckle V.J., Doggett N.A., Flint J., Higgs D.R.
      Hum. Mol. Genet. 10:339-352(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.
      , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
      Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Tissue: Brain.
    8. "IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity."
      Huang J., Song D., Flores A., Zhao Q., Mooney S.M., Shaw L.M., Lee F.S.
      Biochem. J. 401:341-352(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, TISSUE SPECIFICITY.
    9. "A role for IOP1 in mammalian cytosolic iron-sulfur protein biogenesis."
      Song D., Lee F.S.
      J. Biol. Chem. 283:9231-9238(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    12. "MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity."
      Stehling O., Vashisht A.A., Mascarenhas J., Jonsson Z.O., Sharma T., Netz D.J., Pierik A.J., Wohlschlegel J.A., Lill R.
      Science 337:195-199(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE CIA COMPLEX.
    13. "MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism."
      Gari K., Leon Ortiz A.M., Borel V., Flynn H., Skehel J.M., Boulton S.J.
      Science 337:243-245(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE CIA COMPLEX.

    Entry informationi

    Entry nameiNARFL_HUMAN
    AccessioniPrimary (citable) accession number: Q9H6Q4
    Secondary accession number(s): A1L385
    , B3KTJ3, Q53GC6, Q96S10, Q9H6J8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 104 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 16
      Human chromosome 16: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3